Results 161 to 170 of about 13,831 (202)

A Noncatalytic Tetrahydrofolate Tight Binding Site Is on the Small Domain of 10-Formyltetrahydrofolate Dehydrogenase

Archives of Biochemistry and Biophysics, 1999
10-Formyltetrahydrofolate dehydrogenase has previously been identified as a tight binding protein of the polyglutamate forms of tetrahydrofolate (R. J. Cook and C. Wagner, Biochemistry 21, 4427-4434, 1982). Each subunit contains two independently folded domains connected by a linking peptide.
Tzu‐Fun Fu, Bruno Maras, Donatella Barra, Verne Schirch   +3 more
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Effects of steroids, folate deprivation and protein deprivation upon tetrahydrofolate dehydrogenase levels in mammalian tissues

Biochimica et Biophysica Acta (BBA) - General Subjects, 1973
Abstract The effects of sex hormones, glucocorticoids, folate and protein deprivation upon tetrahydrofolate dehydrogenase activity in mammalian tissues were studied. In male rats estradiol induced significant increase in the activity of jejunal tetrahydrofolate dehydrogenase but only a slight increase occurred in the jejenum of hormone-treated female
D. R. Makulu, Evelyn Smith, Joseph R. Bertino   +2 more
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Purification and characterization of the methylene tetrahydromethanopterin dehydrogenase MtdB and the methylene tetrahydrofolate dehydrogenase FolD from Hyphomicrobium zavarzinii ZV580

Archives of Microbiology, 2002
Recently, it has been shown that heterotrophic methylotrophic Proteobacteria contain tetrahydrofolate (H(4)F)- and tetrahydromethanopterin (H(4)MPT)-dependent enzymes. Here we report on the purification of two methylene tetrahydropterin dehydrogenases from the methylotroph Hyphomicrobium zavarzinii ZV580. Both dehydrogenases are composed of one type of
Meike Goenrich, Jan Bursy, Eva Hübner, Dietmar Linder, A. C. Schwartz, Julia A. Vorholt   +5 more
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The recovery of liver tetrahydrofolate dehydrogenase activity from inhibition by methotrexate

Biochemical Pharmacology, 1969
Abstract Rat liver tetrahydrofolate dehydrogenase activity in vivo recovers rapidly from inhibition by methotrexate, despite the known stability of the enzyme-inhibitor complex. Control levels of activity are usually regained within 24 hr following a single injection of methotrexate.
Bob Stanley, G.E. Neal, D. Clive Williams   +2 more
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Tetrahydrofolate dehydrogenase in blood cells and in hematopoietic organs of different vertebrate species

Acta Histochemica, 1978
Some general aspects in cytochemical demonstration of the tetrahydrofolate dehydrogenase, concerning the final reaction product, are studied. Steady and variable factors are detected in a comparative study of Vertebrate hemopoiesis: the enzyme exhibits peculiar features in different cell types.
Rosanna Nano, Giuseppe Gerzeli, Paola De Piceis Polver   +2 more
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Improved purification of tetrahydrofolate dehydrogenase from L1210 leukemia by affinity chromatography

Biochimica et Biophysica Acta (BBA) - Enzymology, 1972
Abstract Tetrahydrofolate dehydrogenase (5,6,7,8-tetrahydrofolate:NADP + oxidoreductase, EC 1.5.1.3; formerly known as dihydrofolate reductase) from a high enzyme mutant of L1210 mouse leukemia was purified to homogeneity by a simple two step procedure involving pH 5.1 precipitation of inert protein, and affinity chromatography employing a ...
Paul L. Chello, Arlene R. Cashmore, Samuel A. Jacobs, Joseph R. Bertino   +3 more
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Binding and interconversion of tetrahydrofolates at a single site in the bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase

Biochemistry, 1995
The bifunctional dehydrogenase/cyclohydrolase domain of the human NADP-dependent trifunctional methyleneH4folate dehydrogenase/methenylH4folate cyclohydrolase/formylH4folate synthetase (H4folate = tetrahydrofolate) catalyzes two sequential reactions involved in the interconversion of H4folate derivatives.
Joelle N. Pelletier, Robert E. MacKenzie
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Tetrahydrofolate dehydrogenase from bakers' yeast

Biochemical and Biophysical Research Communications, 1965
Maurice E. Bush, Kenneth Donaldson
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A colorimetric assay system for tetrahydrofolate dehydrogenase

Biochemical Pharmacology, 1968
B.G. Gunlack, G.E. Neal, D. Clive Williams   +2 more
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Activation of tetrahydrofolate dehydrogenase by certain cations

Biochimica et Biophysica Acta, 1962
Joseph R. Bertino
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