Results 151 to 160 of about 13,790 (193)
Redox-Regulated Pathways in Glioblastoma Stem-like Cells: Mechanistic Insights and Therapeutic Implications. [PDF]
Brain SciEsteban-Román NF +6 more
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Purification of tetrahydrofolate dehydrogenase by affinity chromatography
Biochimica Et Biophysica Acta - Biomembranes, 1972Abstract Tetrahydrofolate dehydrogenase (5,6,7,8-tetrahydrofolate:NADP + oxidoreductase, EC 1.5.1.3; formerly known as dihydrofolate reductase) from a subline of the L1210 lymphoma has been purified to apparent homogeneity with high recovery by simple steps using agarose to which the enzyme inhibitor amethopterin was coupled. A crude (NH 4 ) 2 SO 4
J, Gauldie, B L, Hillcoat
exaly +3 more sources
Tetrahydrofolate dehydrogenase cytochemistry in acute lymphoblastic leukemia
European Journal of Haematology, 1988We studied the cytochemical distribution of tetrahydrofolate dehydrogenase (FH4D), an enzyme involved in nucleic acid metabolism and thus in cell proliferation and differentiation processes, in bone marrow blasts from 37 cases of acute lymphoblastic leukemia (ALL), of whom 23 were pediatric patients. 26 cases were analyzed at onset, 11 in relapse.
INVERNIZZI, ROSANGELA +6 more
exaly +3 more sources
In Vitro Antimalarial Activity of Tetrahydrofolate Dehydrogenase Inhibitors
American Journal of Tropical Medicine and Hygiene, 1984Three tetrahydrofolate dehydrogenase (dihydrofolate reductase = EC 1.5.1.3) inhibitors were tested for antimalarial activity against Plasmodium falciparum, using an in vitro radioisotopic technique. Activity of each drug was tested in both normal RPMI medium 1640 and in modified medium (containing no p-aminobenzoic acid and 2.27 X 10(-8) M folic acid ...
D G, Sixsmith +3 more
exaly +3 more sources
The recovery of liver tetrahydrofolate dehydrogenase activity from inhibition by methotrexate
Biochemical Pharmacology, 1969Abstract Rat liver tetrahydrofolate dehydrogenase activity in vivo recovers rapidly from inhibition by methotrexate, despite the known stability of the enzyme-inhibitor complex. Control levels of activity are usually regained within 24 hr following a single injection of methotrexate.
B G, Stanley, G E, Neal, D C, Williams
exaly +3 more sources
Archives of Biochemistry and Biophysics, 1999
10-Formyltetrahydrofolate dehydrogenase has previously been identified as a tight binding protein of the polyglutamate forms of tetrahydrofolate (R. J. Cook and C. Wagner, Biochemistry 21, 4427-4434, 1982). Each subunit contains two independently folded domains connected by a linking peptide.
Tzu Fun Fu +3 more
exaly +4 more sources
10-Formyltetrahydrofolate dehydrogenase has previously been identified as a tight binding protein of the polyglutamate forms of tetrahydrofolate (R. J. Cook and C. Wagner, Biochemistry 21, 4427-4434, 1982). Each subunit contains two independently folded domains connected by a linking peptide.
Tzu Fun Fu +3 more
exaly +4 more sources
Biochimica Et Biophysica Acta - Biomembranes, 1972
Abstract Tetrahydrofolate dehydrogenase (5,6,7,8-tetrahydrofolate:NADP + oxidoreductase, EC 1.5.1.3; formerly known as dihydrofolate reductase) from a high enzyme mutant of L1210 mouse leukemia was purified to homogeneity by a simple two step procedure involving pH 5.1 precipitation of inert protein, and affinity chromatography employing a ...
Chello, P L +3 more
exaly +3 more sources
Abstract Tetrahydrofolate dehydrogenase (5,6,7,8-tetrahydrofolate:NADP + oxidoreductase, EC 1.5.1.3; formerly known as dihydrofolate reductase) from a high enzyme mutant of L1210 mouse leukemia was purified to homogeneity by a simple two step procedure involving pH 5.1 precipitation of inert protein, and affinity chromatography employing a ...
Chello, P L +3 more
exaly +3 more sources
Archives of Microbiology, 2002
Recently, it has been shown that heterotrophic methylotrophic Proteobacteria contain tetrahydrofolate (H(4)F)- and tetrahydromethanopterin (H(4)MPT)-dependent enzymes. Here we report on the purification of two methylene tetrahydropterin dehydrogenases from the methylotroph Hyphomicrobium zavarzinii ZV580. Both dehydrogenases are composed of one type of
Julia A Vorholt
exaly +4 more sources
Recently, it has been shown that heterotrophic methylotrophic Proteobacteria contain tetrahydrofolate (H(4)F)- and tetrahydromethanopterin (H(4)MPT)-dependent enzymes. Here we report on the purification of two methylene tetrahydropterin dehydrogenases from the methylotroph Hyphomicrobium zavarzinii ZV580. Both dehydrogenases are composed of one type of
Julia A Vorholt
exaly +4 more sources