Results 161 to 170 of about 8,933 (186)
Some of the next articles are maybe not open access.

The recovery of liver tetrahydrofolate dehydrogenase activity from inhibition by methotrexate

Biochemical Pharmacology, 1969
Abstract Rat liver tetrahydrofolate dehydrogenase activity in vivo recovers rapidly from inhibition by methotrexate, despite the known stability of the enzyme-inhibitor complex. Control levels of activity are usually regained within 24 hr following a single injection of methotrexate.
G E Neal
exaly   +3 more sources

Improved purification of tetrahydrofolate dehydrogenase from L1210 leukemia by affinity chromatography

Biochimica Et Biophysica Acta - Biomembranes, 1972
Abstract Tetrahydrofolate dehydrogenase (5,6,7,8-tetrahydrofolate:NADP + oxidoreductase, EC 1.5.1.3; formerly known as dihydrofolate reductase) from a high enzyme mutant of L1210 mouse leukemia was purified to homogeneity by a simple two step procedure involving pH 5.1 precipitation of inert protein, and affinity chromatography employing a ...
Paul L Chello   +2 more
exaly   +3 more sources

The detoxification of formic acid by 10-formyl tetrahydrofolate dehydrogenase in Apis mellifera: capabilities and mechanism [PDF]

open access: yes, 2023
Important ecological und economic functions are performed by different pollinators. Apis mellifera being one of the most important ones, as it is managed by beekeepers worldwide. In recent years, the obligate ectoparasite Varroa destructor grew of importance as the impact on honey bee hives grew more apparent, as research has shown that it not only ...
Mating, Moritz
openaire   +2 more sources

Purification and characterization of the methylene tetrahydromethanopterin dehydrogenase MtdB and the methylene tetrahydrofolate dehydrogenase FolD from Hyphomicrobium zavarzinii ZV580

Archives of Microbiology, 2002
Recently, it has been shown that heterotrophic methylotrophic Proteobacteria contain tetrahydrofolate (H(4)F)- and tetrahydromethanopterin (H(4)MPT)-dependent enzymes. Here we report on the purification of two methylene tetrahydropterin dehydrogenases from the methylotroph Hyphomicrobium zavarzinii ZV580. Both dehydrogenases are composed of one type of
Dietmar Linder   +2 more
exaly   +4 more sources

Effects of steroids, folate deprivation and protein deprivation upon tetrahydrofolate dehydrogenase levels in mammalian tissues

Biochimica Et Biophysica Acta - General Subjects, 1973
Abstract The effects of sex hormones, glucocorticoids, folate and protein deprivation upon tetrahydrofolate dehydrogenase activity in mammalian tissues were studied. In male rats estradiol induced significant increase in the activity of jejunal tetrahydrofolate dehydrogenase but only a slight increase occurred in the jejenum of hormone-treated female
D R, Makulu, E F, Smith, J R, Bertino
exaly   +3 more sources

The N-terminal, dehydrogenase/cyclohydrolase domain of yeast cytoplasmic trifunctional C1-tetrahydrofolate synthase requires the C-terminal, synthetase domain for the catalytic activity in vitro

open access: yesFEBS Letters, 1995
The yeast ADE3(1–333) gene which encodes a truncated protein containing the N-terminal 5,10-methylene-tetrahydrofolate (THF) dehydrogenase (D)/5,10-methynyl-THF cyclohydrolase (C) domain of cytoplasmic trifunctional C1-THF synthase is able to complement ...
Jae Mahn Song, J C Rabinowitz
exaly   +2 more sources

Tetrahydrofolate Dehydrogenase Cytochemistry and Classification of Acute Leukaemia

Acta Haematologica, 2009
Bone marrow and blood smears from patients with acute lymphoblastic and myeloblastic leukaemia prior to therapy were stained for tetrahydrofolate dehydrogenase. Compared with other cytochemical tests this reaction seems to discriminate clearly between cells with myeloid and lymphoid features.
NANO, ROSANNA   +3 more
openaire   +2 more sources

A critical examination of some histochemical methods for demonstrating tetrahydrofolate dehydrogenase

The Histochemical Journal, 1972
Two different methods, one proposed by us (1969, 1970) and the other by Onicescuet al. (1970), for the histochemical demonstration of tetrahydrofolate dehydrogenase have been compared using as test materials frozen sections of mouse liver and blood smears of laboratory animals that had been infected experimentally with malaria.
G, Gerzeli, P, De Piceis Polver
openaire   +2 more sources

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