Tetrahymena meiosis: Simple yet ingenious.
PLoS Genetics, 2021 The presence of meiosis, which is a conserved component of sexual reproduction, across organisms from all eukaryotic kingdoms, strongly argues that sex is a primordial feature of eukaryotes.
Josef Loidl
doaj +5 more sources
Whats, hows and whys of programmed DNA elimination in Tetrahymena [PDF]
Open Biology, 2017 Programmed genome rearrangements in ciliates provide fascinating examples of flexible epigenetic genome regulations and important insights into the interaction between transposable elements (TEs) and host genomes.
Tomoko Noto, Kazufumi Mochizuki
doaj +2 more sources
Nucleus-specific linker histones Hho1 and Mlh1 form distinct protein interactions during growth, starvation and development in Tetrahymena thermophila [PDF]
Scientific Reports, 2019 Chromatin organization influences most aspects of gene expression regulation. The linker histone H1, along with the core histones, is a key component of eukaryotic chromatin.
Pearlman, Ronald E. +7 more
core +2 more sources
Hidden genomic evolution in a morphospecies-The landscape of rapidly evolving genes in Tetrahymena.
PLoS Biology, 2019 A morphospecies is defined as a taxonomic species based wholly on morphology, but often morphospecies consist of clusters of cryptic species that can be identified genetically or molecularly.
Jie Xiong +16 more
doaj +2 more sources
Epigenetics & Chromatin, 2018 Background The chromatin remodelers of the SWI/SNF family are critical transcriptional regulators. Recognition of lysine acetylation through a bromodomain (BRD) component is key to SWI/SNF function; in most eukaryotes, this function is attributed to SNF2/
Alejandro Saettone +9 more
doaj +3 more sources
Tetrahymena ATG8 homologs, TtATG8A and TtATG8B, are responsible for mitochondrial degradation induced by starvation [PDF]
mBioThe majority of heterotrophic unicellular eukaryotes have evolved mechanisms to survive periods of starvation, allowing them to endure until conditions are favorable for regrowth.
Shinya Matsuda +5 more
doaj +2 more sources
Structural basis of template-boundary definition in Tetrahymena telomerase. [PDF]
Nature Structural &Molecular Biology, 2015 Telomerase is required to maintain repetitive G-rich telomeric DNA sequences at chromosome ends. To do so, the telomerase reverse transcriptase (TERT) subunit reiteratively uses a small region of the integral telomerase RNA (TER) as a template.
Akiyama, Ben M +5 more
core +3 more sources
A novel malaria vaccine candidate antigen expressed in Tetrahymena thermophila. [PDF]
PLoS ONE, 2014 Development of effective malaria vaccines is hampered by the problem of producing correctly folded Plasmodium proteins for use as vaccine components.
Graeme J M Cowan +7 more
doaj +4 more sources
Metabolomics’ Change Under β-Cypermethrin Stress and Detoxification Role of CYP5011A1 in Tetrahymena thermophila [PDF]
MetabolitesBackground: β-cypermethrin (β-CYP) exhibits high toxicity to aquatic organisms and poses significant risks to aquatic ecosystems. Tetrahymena thermophila, a protozoa widely distributed in aquatic environments, can tolerate high concentrations of β ...
Wenyong Zhang +4 more
doaj +2 more sources
bioRxiv, 2022 Using cryo-EM, the authors identified 42 MIPs, including outer junction protein CFAP77 and outer dense fibers, in native doublet microtubules of Tetrahymena thermophila . Knockout of CFAP77 reduced ciliary beat frequency and led to outer junction damage.
S. Kubo +13 more
semanticscholar +1 more source