Results 1 to 10 of about 47,911 (258)

The bromodomain-containing protein Ibd1 links multiple chromatin-related protein complexes to highly expressed genes in Tetrahymena thermophila [PDF]

Epigenetics & Chromatin, 2018
Background The chromatin remodelers of the SWI/SNF family are critical transcriptional regulators. Recognition of lysine acetylation through a bromodomain (BRD) component is key to SWI/SNF function; in most eukaryotes, this function is attributed to SNF2/
Alejandro Saettone, Jyoti Garg, Jean-Philippe Lambert, Syed Nabeel-Shah, Marcelo Ponce, Alyson Burtch, Cristina Thuppu Mudalige, Anne-Claude Gingras, Ronald E. Pearlman, Jeffrey Fillingham   +9 more
doaj   +4 more sources

Development of a Tetrahymena thermophila-Based Vaccine Expressing Miamiensis avidus Ciliary Proteins to Combat Scuticociliatosis. [PDF]

J Fish Dis
ABSTRACT Miamiensis avidus is a parasitic pathogen responsible for scuticociliatosis, a lethal infection affecting marine fish worldwide, including Japanese flounder. Immunisation with formalin‐killed M. avidus has shown promise in inducing protective immunity, positioning it as a potential vaccine candidate against scuticociliatosis.
Watanabe Y, Kotake M, Matsuoka H, Yoshinaga T, Kitamura SI.   +4 more
europepmc   +2 more sources

RACS: Rapid Analysis of ChIP-Seq data for contig based genomes [PDF]

BMC Bioinformatics 20, 533 (2019), 2019
Background: Chromatin immunoprecipitation coupled to next generation sequencing (ChIP-Seq) is a widely used technique to investigate the function of chromatin-related proteins in a genome-wide manner. ChIP-Seq generates large quantities of data which can be difficult to process and analyse, particularly for organisms with contig based genomes.
Fillingham, Jeffrey, Nabeel-Shah, Syed, Ponce, Marcelo, Saettone, Alejandro   +3 more
arxiv   +3 more sources

A Reassessment of Phylogenetic Relationships in Class Oligohymenophorea (Protista, Ciliophora) Based on Updated Multigene Data. [PDF]

Ecol Evol
We report 97 new sequences, including SSU‐rRNA, ITS1‐5.8S‐ITS2 rRNA, LSU‐rRNA, mitochondrial cytochrome oxidase c subunit I, and mitochondrial small subunit ribosomal RNA genes of 30 oligohymenophorean populations. A comprehensive analysis of class Oligohymenophorea is conducted, encompassing 250 populations.
Li B, Song Y, Wang X, Zhao Q, Liu M, Liu L, Pan X, Yi Z.   +7 more
europepmc   +2 more sources

Equilibrium properties and force-driven unfolding pathways of RNA molecules [PDF]

Phys. Rev. Lett. 103: 188102 (2009), 2009
The mechanical unfolding of a simple RNA hairpin and of a 236--bases portion of the Tetrahymena thermophila ribozyme is studied by means of an Ising--like model. Phase diagrams and free energy landscapes are computed exactly and suggest a simple two--state behaviour for the hairpin and the presence of intermediate states for the ribozyme ...
A. Imparato, A. Pelizzola, M. Müller, M. Zamparo   +3 more
arxiv   +3 more sources

Pathways and kinetic barriers in mechanical unfolding and refolding of RNA and proteins [PDF]

Structure (2006) vol 14. 1633-1645, 2006
Using self-organized polymer models, we predict mechanical unfolding and refolding pathways of ribo-zymes, and the green fluorescent protein. In agreement with experiments, there are between six and eight unfolding transitions in the Tetrahymena ribozyme.
Dima, Ruxandra I, Hyeon, Changbong, Thirumalai, D.   +2 more
arxiv   +4 more sources

A novel malaria vaccine candidate antigen expressed in Tetrahymena thermophila. [PDF]

PLoS ONE, 2014
Development of effective malaria vaccines is hampered by the problem of producing correctly folded Plasmodium proteins for use as vaccine components.
Graeme J M Cowan, Ulrike Bockau, Janna Eleni-Muus, Ingo Aldag, Kay Samuel, Alison M Creasey, Marcus W W Hartmann, David R Cavanagh   +7 more
doaj   +4 more sources

Metabolomics’ Change Under β-Cypermethrin Stress and Detoxification Role of CYP5011A1 in Tetrahymena thermophila [PDF]

Metabolites
Background: β-cypermethrin (β-CYP) exhibits high toxicity to aquatic organisms and poses significant risks to aquatic ecosystems. Tetrahymena thermophila, a protozoa widely distributed in aquatic environments, can tolerate high concentrations of β ...
Wenyong Zhang, Wenliang Lei, Tao Bo, Jing Xu, Wei Wang   +4 more
doaj   +2 more sources

A split ribozyme system for in vivo plant RNA imaging and genetic engineering. [PDF]

Plant Biotechnol J
Summary RNA plays a central role in plants, governing various cellular and physiological processes. Monitoring its dynamic abundance provides a discerning understanding of molecular mechanisms underlying plant responses to internal (developmental) and external (environmental) stimuli, paving the way for advances in plant biotechnology to engineer crops
Liu Y, Rajput R, Islam MT, Valle ID, Yao T, Agrawal R, Boone BA, Eckert CA, Abraham PE, Chen JG, Tuskan GA, Yang X.   +11 more
europepmc   +2 more sources

Temporal Changes in the Role of Species Sorting and Evolution Determine Community Dynamics. [PDF]

Ecol Lett
Evolutionary change within community members and shifts in species composition contribute to community and trait dynamics. To integrate when and how both processes structure communities, we estimated the contributions of species sorting and evolution over time (60 days) in bacterial communities of 24 species under selection by a ciliate predator ...
Hoffmann J, Hogle S, Hiltunen T, Becks L.   +3 more
europepmc   +2 more sources