Results 91 to 100 of about 50,736 (296)

A Small Family of Elements with Long Inverted Repeats is Located Near Sites of Developmentally Regulated DNA Rearrangement in \u3cem\u3eTetrahymena thermophila\u3c/em\u3e [PDF]

open access: yes, 1994
Extensive DNA rearrangement occurs during the development of the somatic macronucleus from the germ line micronucleus in ciliated protozoans. The micronuclear junctions and the macronuclear product of a developmentally regulated DNA rearrangement in ...
Berger, Patricia J.   +4 more
core   +1 more source

Equilibrium properties and force-driven unfolding pathways of RNA molecules

open access: yes, 2009
The mechanical unfolding of a simple RNA hairpin and of a 236--bases portion of the Tetrahymena thermophila ribozyme is studied by means of an Ising--like model.
A. Imparato   +3 more
core   +1 more source

Inhibition and relaxation of sea urchin sperm flagella by vanadate [PDF]

open access: yes, 1980
Direct measurements of the stiffness (elastic bending resistance) of demembranated sera urchin sperm flagella were made in the presence of MgATP2- and vanadate.
Okuno, Makoto
core   +3 more sources

Nonsense-mediated mRNA decay in Tetrahymena is EJC independent and requires a protozoa-specific nuclease

open access: yesNucleic Acids Research, 2017
Nonsense-mediated mRNA decay (NMD) is essential for removing premature termination codon-containing transcripts from cells. Studying the NMD pathway in model organisms can help to elucidate the NMD mechanism in humans and improve our understanding of how
Miao Tian   +6 more
semanticscholar   +1 more source

Targeting the TRIM28–EZH2 Protein–Protein Interface With Cysteine‐Reactive Covalent Inhibitors: A Computational Blueprint for Cancer Therapy

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
Graphical overview of the computational strategy employed to disrupt the oncogenic TRIM28EZH2 proteinprotein interaction. The workflow illustrates proteinprotein docking to define the interaction interface, cysteine‐focused covalent virtual screening targeting EZH2 Cys144, covalent docking, molecular dynamics simulations, and MM‐GBSA binding free ...
Ibrahim Oluwatobi Kehinde   +4 more
wiley   +1 more source

Determination of the Lethal Concentrations of Two Phenolic Acid Derivatives Originated From the Edible Red Marine Macroalga (Bangia fuscopurpurea) Using the In Vivo Zebrafish Eleutheroembryo Model and Their In Silico Structure–Toxicity Relationship Study

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
This study compared the predicted and experimental toxicity of two phenolic acid derivatives (HBP2 and HBP3) from the edible macroalga Bangia fuscopurpurea. HBP2 exhibited greater in vivo safety and lower predicted toxicity risks in silico, whereas HBP3 displayed higher in vitro cytotoxicity in IMR‐32 cells, potentially associated with the ...
Shi‐Ying Huang   +7 more
wiley   +1 more source

The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila

open access: yesGenes & Development, 2016
Here, Cheng et al. present data from Tetrahymena that highlight a division of labor among ciliate piggyBac-derived genes, which carry out mutually exclusive categories of excision events mediated by either transposon-like features or RNA-directed ...
Chao-Yin Cheng   +5 more
semanticscholar   +1 more source

Grazer‐induced bioluminescence and toxicity in marine dinoflagellates

open access: yesLimnology and Oceanography, Volume 70, Issue 12, Page 3769-3783, December 2025.
Abstract Marine copepods are the most abundant multicellular zooplankton in the global oceans. They imprint their surrounding waters with a unique bouquet of chemical compounds, including polar lipids such as copepodamides. Prey organisms can detect copepodamides and respond by inducing defensive traits including bioluminescence, toxin production ...
Paula Gonzalo‐Valmala   +3 more
wiley   +1 more source

Fusion Pores as Regulators of Quantal Size and Cellular Physiology

open access: yesBioEssays, Volume 47, Issue 11, November 2025.
During regulated exocytosis, membrane fusion regulatory factors act directly on SNAREs and membrane lipids to control fusion pore dynamics. This, in turn, leads to a differential amount of cargo release (referred to in this article as “quantal size”) across various cell types, thereby triggering distinct physiological cues.
Bhavya R. Bhaskar   +3 more
wiley   +1 more source

Lectins and Tetrahymena – A review [PDF]

open access: yes, 2016
The unicellular ciliate Tetrahymena is a complete organism, one of the most highly developed protozoans, which has specialized organelles performing each of the functions characteristic to the cells of higher ranked animals.
Csaba, György
core   +1 more source

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