Results 81 to 90 of about 50,736 (296)

Beyond bacterial defences: the role of lysozyme in cancer

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Lysozyme (LYZ) is a multi‐functional secreted factor that encompasses both antibacterial and immunomodulatory functions. Emerging evidence highlights its complex role in tumour progression by directly influencing tumour cells and modulating the immune microenvironment.
Lei Wang, Qian Dong, Fuchu He, Zhiwen Gu, Aihua Sun   +4 more
wiley   +1 more source

Improved Method for DNA Extraction and Purification from Tetrahymena pyriformis

Methods and Protocols, 2019
Tetrahymena pyriformis (protozoa) is intensely investigated as a model organism, offering numerous advantages in comprehensive and multidisciplinary studies using morphologic or molecular methods.
Ezzouhra El Maaiden, Youssef El Kharrassi, Abdel Khalid Essamadi, Khadija Moustaid, Boubker Nasser   +4 more
doaj   +1 more source

Effects of six pyrimidine analogs on the growth of Tetrahymena thermophila and their implications in pyrimidine metabolism.

PLoS ONE, 2023
Tetrahymena are ciliated protists that have been used to study the effects of toxic chemicals, including anticancer drugs. In this study, we tested the inhibitory effects of six pyrimidine analogs (5-fluorouracil, floxuridine, 5'-deoxy-5-fluorouridine, 5-
Zander Harpel, Wei-Jen Chang, Jacob Circelli, Richard Chen, Ian Chang, Jason Rivera, Stephanie Wu, RongHan Wei   +7 more
doaj   +1 more source

Histone methyltransferase TXR1 is required for both H3 and H3.3 lysine 27 methylation in the well-known ciliated protist Tetrahymena thermophila

Science China Life Sciences, 2017
DNA replication elongation is tightly controlled by histone-modifying enzymes. Our previous studies showed that the histone methytransferase TXR1 (Tetrahymena Trithorax related protein 1) specifically catalyzes H3K27 monomethylation and affects DNA ...
Xiaolu Zhao, Yuanyuan Wang, Yurui Wang, Yifan Liu, Shan Gao   +4 more
semanticscholar   +1 more source

The absence of both RIBC1 and RIBC2 induces decreased sperm motility and litter size in male mice

Andrology, Volume 14, Issue 2, Page 545-554, February 2026.
Abstract Background RIBC1 (RIB43A domain with coiled‐coils 1) and RIBC2 (RIB43A domain with coiled‐coils 2) are homolog proteins of RIB43a which is localized to microtubules in the cilia and flagella of unicellular organisms. Cryo‐electron microscopy and artificial intelligence studies showed that RIBC1 and RIBC2 are microtubule inner proteins (MIPs ...
Kento Katsuma, Keisuke Shimada, Shingo Tonai, Daisuke Mashiko, Rie Iida‐Norita, Yuki Kaneda, Haruhiko Miyata, Masahito Ikawa   +7 more
wiley   +1 more source

Exploring the Histone Acetylation Cycle in the Protozoan Model Tetrahymena thermophila

Frontiers in Cell and Developmental Biology, 2020
The eukaryotic histone acetylation cycle is composed of three classes of proteins, histone acetyltransferases (HATs) that add acetyl groups to lysine amino acids, bromodomain (BRD) containing proteins that are one of the most characterized of several ...
Suzanne Wahab, Alejandro Saettone, Syed Nabeel-Shah, Nora Dannah, Jeffrey Fillingham   +4 more
doaj   +1 more source

Differential Assembly of Catalytic Interactions within the Conserved Active Sites of Two Ribozymes. [PDF]

PLoS ONE, 2016
Molecular recognition is central to biology and a critical aspect of RNA function. Yet structured RNAs typically lack the preorganization needed for strong binding and precise positioning.
Sabine N S van Schie, Raghuvir N Sengupta, Daniel Herschlag   +2 more
doaj   +1 more source

A Family of Developmentally Excised DNA Elements in \u3cem\u3eTetrahymena\u3c/em\u3e is under Selective Pressure to Maintain an Open Reading Frame Encoding an Integrase-Like Protein [PDF]

, 2000
Tlr1 is a member of a family of ~20-30 DNA elements that undergo developmentally regulated excision during formation of the macronucleus in the ciliated protozoan Tetrahymena.
Gershan, Jill A., Karrer, Kathleen M.
core   +1 more source

The Mechanisms of Codon Reassignments in Mitochondrial Genetic Codes [PDF]

, 2007
Many cases of non-standard genetic codes are known in mitochondrial genomes. We carry out analysis of phylogeny and codon usage of organisms for which the complete mitochondrial genome is available, and we determine the most likely mechanism for codon ...
A Reyes, A Schneider, AM Nedelcu, AM Simpson, AP Sibler, BF Lang, C Gissi, CA Lozupone, CE Bullerwell, D Urbina, DH Ardell, DV Lavrov, DW Schultz, DW Schultz, E Seif, E Talla, EM Denovan-Wright, FHC Crick, G Burger, G Burger, G Burger, H Asahara, HS Kim, J Castrasena, J Matsugi, J Swire, JD Alfonzo, JL Blanchard, JL Boore, K Hancock, K Tomita, Knight, Knight, M Ehara, M Ehara, M Kimura, M Nohara, M Turmel, MAS Santos, MAS Santos, ME Saks, MJ Laforest, MJ Telford, MV Sanchez Puerta, N Spruyt, NJ Savill, Paul G. Higgs, PG Higgs, PG Higgs, PJ Keeling, PS Lovett, R Giegé, R Koszul, RC Morris, S Kerscher, S Matsuyama, S Osawa, S Osawa, S Osawa, S Sengupta, S Yokobori, SE Massey, SG Andersson, SG Andersson, SJ Freeland, Supratim Sengupta, T Muramatsu, Tomita, Tomita, U Kück, Xiaoguang Yang, Y Hayashi-Ishimaru, Y Hayashi-Ishimaru, Y Inagaki, Y Kuchino   +74 more
core   +4 more sources

From isolation to insights: mitochondrial complex I in the diatom Phaeodactylum tricornutum

The Plant Journal, Volume 125, Issue 3, February 2026.
SUMMARY Diatoms are among the most ecologically successful microalgae, contributing significantly to marine primary production and global carbon cycling. Their distinctive metabolic architecture, shaped by a complex evolutionary history involving secondary endosymbiosis, includes a highly compartmentalized cell organization and unique metabolic ...
Federico Berdun, Jennifer Senkler, Michael Senkler, Noah Ditz, Eva Plönnigs, Thomas Reinard, Eduardo Zabaleta, Hans‐Peter Braun   +7 more
wiley   +1 more source