Results 131 to 140 of about 1,048 (196)

Dendritic ZSM-5 zeolites as highly active catalysts for the valorization of monoterpene epoxides.

open access: yesGreen Chem
Gallego-Villada LA   +6 more
europepmc   +1 more source

The Growth of Tetraoxane Crystals from Acetone Solutions

open access: yesThe Growth of Tetraoxane Crystals from Acetone Solutions
openaire  

Chemometric methods in antimalarial drug design from 1,2,4,5-tetraoxanes analogues

open access: yesSAR and QSAR in Environmental Research, 2020
A set of 23 steroidal 1,2,4,5-tetraoxane analogues were studied using quantum-chemical method (B3LYP/6-31 G*) and multivariate analyses (PCA, HCA, KNN and SIMCA) in order to calculate the properties and correlate them with antimalarial activity (log RA ...
E. B. Costa   +14 more
semanticscholar   +3 more sources
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Antimalarial and Anticancer Activity Evaluation of Bridged Ozonides, Aminoperoxides, and Tetraoxanes

ChemMedChem, 2022
Bridged aminoperoxides, for the first time, were investigated for the in vitro antimalarial activity against the chloroquine‐resistant Plasmodium falciparum strain K1 and for their cytotoxic activities against immortalized human normal liver (LO2) and ...
P. Coghi   +11 more
semanticscholar   +3 more sources

Medicinal chemistry perspectives of trioxanes and tetraoxanes.

Current Medicinal Chemistry, 2011
Trioxane based compounds such as artemisinin and its synthetic and semi-synthetic analogues constitute promising class of antimalarial agents. The pharmaceutical development of artemisinin was started in 1971 after the isolation from Chinese medicinal ...
N. Kumar, Manik Sharma, D. Rawat
semanticscholar   +3 more sources

Tetraoxanes as antimalarials: harnessing the endoperoxide.

Mini-Reviews in Medicinal Chemistry, 2014
With the emergence of resistance to artemesinin, the need for new antimalarial compounds is pressing. Several research groups have made significant contributions to the exploration of the use of 1,2,4,5-tetraoxanes and 1,2,4- trioxanes as synthetic analogues of artemesinin.
Laura C. Fisher, M. Blackie
semanticscholar   +3 more sources

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