Suspension Polymerization of Tetraoxane in Solid State Catalyzed by BF3O (C2H5) 2
Eiichi Kobayashi +2 more
openalex +2 more sources
Controlling schistosomiasis with praziquantel: How much longer without a viable alternative? [PDF]
Bergquist R, Utzinger J, Keiser J.
europepmc +1 more source
An evaluation of the cytotoxicity of the dihydroartemisinin-acridine hybrids and tetra-oxane dimmers against leukaemia and colon cancer cells lines ‘1’ [PDF]
Rinki, Rinki
core
Dendritic ZSM-5 zeolites as highly active catalysts for the valorization of monoterpene epoxides.
Gallego-Villada LA +6 more
europepmc +1 more source
Identification of novel ligands of human cytochromes P450 among steroidal 1,2,4,5-tetraoxanes [PDF]
D. Chebotkova +3 more
openalex
The Growth of Tetraoxane Crystals from Acetone Solutions
openaire
Chemometric methods in antimalarial drug design from 1,2,4,5-tetraoxanes analogues
A set of 23 steroidal 1,2,4,5-tetraoxane analogues were studied using quantum-chemical method (B3LYP/6-31 G*) and multivariate analyses (PCA, HCA, KNN and SIMCA) in order to calculate the properties and correlate them with antimalarial activity (log RA ...
E. B. Costa +14 more
semanticscholar +3 more sources
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Antimalarial and Anticancer Activity Evaluation of Bridged Ozonides, Aminoperoxides, and Tetraoxanes
ChemMedChem, 2022Bridged aminoperoxides, for the first time, were investigated for the in vitro antimalarial activity against the chloroquine‐resistant Plasmodium falciparum strain K1 and for their cytotoxic activities against immortalized human normal liver (LO2) and ...
P. Coghi +11 more
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Medicinal chemistry perspectives of trioxanes and tetraoxanes.
Current Medicinal Chemistry, 2011Trioxane based compounds such as artemisinin and its synthetic and semi-synthetic analogues constitute promising class of antimalarial agents. The pharmaceutical development of artemisinin was started in 1971 after the isolation from Chinese medicinal ...
N. Kumar, Manik Sharma, D. Rawat
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Tetraoxanes as antimalarials: harnessing the endoperoxide.
Mini-Reviews in Medicinal Chemistry, 2014With the emergence of resistance to artemesinin, the need for new antimalarial compounds is pressing. Several research groups have made significant contributions to the exploration of the use of 1,2,4,5-tetraoxanes and 1,2,4- trioxanes as synthetic analogues of artemesinin.
Laura C. Fisher, M. Blackie
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