Results 161 to 170 of about 997 (192)

Phosphomolybdic and phosphotungstic acids as efficient catalysts for the synthesis of bridged 1,2,4,5-tetraoxanes from β-diketones and hydrogen peroxide.

Organic and biomolecular chemistry, 2013
Phosphomolybdic acid (PMA) and phosphotungstic acid (PTA) efficiently catalyze the addition of H2O2 to β-diketones to form bridged 1,2,4,5-tetraoxanes.
A. Terent’ev, I. Yaremenko, V. Vil’, I. K. Moiseev, S. A. Kon’kov, V. Dembitsky, D. Levitsky, G. Nikishin   +7 more
semanticscholar   +1 more source

New Chimeric Antimalarials with 4-Aminoquinoline Moiety Linked to a Tetraoxane Skeleton [PDF]

Journal of Medicinal Chemistry, 2008
The synthesis of the chimeric molecules consisting of two pharmacophores, tetraoxane and 7-chloro-4-aminoquinoline, is reported. The tetraoxanes 2, 4, and 8 show relatively potent in vitro antimalarial activities, with IC90 values for the Plasmodium falciparum strain W2 of 2.26, 12.44, and 10.74 nM, respectively.
Opsenica, Igor, Opsenica, Dejan, Lanteri, C.A., Anova, L., Milhous, Wilbur K., Smith, K. S., Šolaja, Bogdan   +6 more
openaire   +4 more sources

The effect of the structure of mixed tetraoxanes on their chromatographic behavior on different adsorbents

Journal of Planar Chromatography – Modern TLC, 2004
The retention behavior of 29 biologically active compounds, mixed 1,2,4,5-tetraoxanes, has been investigated by thin-layer chromatography on unmodified silica, CN-silica, and RP-18-silica. The binary mobile phases ethyl acetate-petroleum ether and ethyl acetate-toluene were used under normal-phase conditions and water-organic modifier (methanol ...
Gaica, Sandra, Opsenica, Dejan, Šolaja, Bogdan, Tešić, Živoslav, Milojković-Opsenica, Dušanka   +4 more
openaire   +4 more sources

N-sulfonylpiperidinedispiro-1,2,4,5-tetraoxanes exhibit potent in vitro antiplasmodial activity and in vivo efficacy in mice infected with P. berghei ANKA.

European journal of medicinal chemistry, 2022
Preeti Singh, Chiranjeev Sharma, B. Sharma, A. Mishra, Drishti Agarwal, Deepika Kannan, Jana Held, Shailja Singh, S. Awasthi   +8 more
semanticscholar   +1 more source

Radiation‐induced solid state polymerization of tetraoxane

Journal of Polymer Science Part B: Polymer Letters, 1963
The radioinduced polymerization of tetraoxane is reported and compared with that of trioxane. Under gamma irradiation at 80 deg C and at a dose rate of 2.5 x 10/sup 4/ r/hr, tetraoxane became gradually opaque. After 18 hr irradiation a polymer crystal with the shape of the monomer crystal was obtained at 94% conversion. However, no polymer was obtained
M. Nishii, H. Ochi, Koichiro Hayashi, Y. Miyake, S. Okamura   +4 more
openaire   +2 more sources

Comparison of the reactivity of antimalarial 1,2,4,5-tetraoxanes with 1,2,4-trioxolanes in the presence of ferrous iron salts, heme, and ferrous iron salts/phosphatidylcholine.

Journal of Medicinal Chemistry, 2011
Dispiro-1,2,4,5-tetraoxanes and 1,2,4-trioxolanes represent attractive classes of synthetic antimalarial peroxides due to their structural simplicity, good stability, and impressive antimalarial activity.
Fatima Bousejra-El Garah, Michael H. L. Wong, R. Amewu, Sant Muangnoicharoen, J. Maggs, J. Stigliani, B. Park, James Chadwick, S. Ward, P. O’Neill   +9 more
semanticscholar   +1 more source

Mixed steroidal tetraoxanes induce apoptotic cell death in tumor cells

Investigational New Drugs, 2008
In this study we investigated the antiproliferative activity of six mixed steroidal tetraoxanes against various tumor cell lines, the toxicity against normal peripheral blood mononuclear cells (PBMC), and the mode of HeLa cell death induced by these compounds.
Žižak, Željko, Juranić, Zorica, Opsenica, Dejan, Šolaja, Bogdan   +3 more
openaire   +5 more sources

Effect of Polymerization Temperature on the Texture of Poly (tetraoxane)

Japanese Journal of Applied Physics, 1977
Yoshiaki Nakase, Naohiro Hayakawa, Isamu Kuriyama, Akira Odajima   +3 more
openalex   +3 more sources

Correlation between structure, retention and activity of cholic acid derived cis-trans isomeric bis-steroidal tetraoxanes.

Journal of Separation Science, 2011
Both quantitative structure-retention (QSRR) and quantitative structure-activity relationship (QSAR) studies have been performed to correlate the molecular characteristics of seven pairs of cis-trans isomeric bis-steroidal tetraoxanes with their reversed-
Sandra Šegan, F. Andrić, Aleksandra Radoičić, D. Opsenica, B. Šolaja, M. Zlatović, D. Milojković-Opsenica   +6 more
semanticscholar   +1 more source

Different behavior of artemisinin and tetraoxane in the oxidative degradation of phospholipid

Chemistry and Physics of Lipids, 2009
The reaction of trioxane and tetraoxane endoperoxides with unsaturated phospholipid 1 in the presence of Fe(II) was investigated in the absence of oxygen by means of tandem ESI-MS analysis. The spectral analyses for the reaction mixtures showed that artemisinin 2 with a trioxane structure gave no peak except that for the remaining intact phospholipid 1
Hirotaka Furukawa, Minoru Izumi, Hye Sook Kim, Arnold N. Onyango, Hideyuki Ito, Naomichi Baba, Tsutomu Hatano, Naokazu Kumura, Shuhei Nakajima, Yusuke Wataya   +9 more
openaire   +3 more sources