Results 31 to 40 of about 1,048 (196)
7,8,15,16-tetraoxa-dispiro[5.2.5.2]hexadecane-3-carboxylic acid derivatives and their antimalarial activity [PDF]
Journal of the Serbian Chemical Society, 2004 Several C2 symmetrical mixed tetraoxanes were prepared starting from a gemdihydroperoxide and a ketone. The obtained tetraoxanes showed pronounced antimalarial activity against P. falciparum chloroquine resistant W2 and chloroquine susceptible D6 strains,
BOGDAN SOLAJA +4 more
doaj +3 more sources
Diversified Synthesis of N-Benzoyl Piperidine Tetraoxane Analogues Using Molybdenum Trioxide as a Newer Catalyst and Its Antiplasmodial Activity. [PDF]
ACS OmegaKumar A +4 more
europepmc +3 more sources
On peroxide antimalarials [PDF]
Journal of the Serbian Chemical Society, 2007 Several dicyclohexylidene tetraoxanes were prepared in order to gain a further insight into structure–activity relationship of this kind of antimalarials.
IGOR OPSENICA +6 more
doaj +3 more sources
3D-QSAR Studies of Tetraoxanes Derivatives as Antimalarial Agents Using CoMFA and CoMSIA Approaches
, 2013 Taigang Liang, L. Ren, Qingshan Li
semanticscholar +3 more sources
Journal of the Serbian Chemical Society, 2009 The problem of endemic malaria continues unabated globally. Malaria affects 40 % of the global population, causing an estimated annual mortality of 1.5–2.7 million people.
DEJAN M. OPSENICA, BOGDAN A. ŠOLAJA
doaj +3 more sources
Assessment of the antimalarial potential of tetraoxane WR 148999. [PDF]
The American journal of tropical medicine and hygiene, 2000 The antimalarial peroxide, dispiro-1,2,4,5-tetraoxane WR 148999, was synergistic with chloroquine, quinine, mefloquine, and artemisinin against both D6 and W2 clones of Plasmodium falciparum. In consideration of the contrasting antagonism between artemisinin and chloroquine, these drug combination data imply that WR 148999 and artemisinin may not share
Jonathan L. Vennerstrom +7 more
openalex +3 more sources
ChemMedChem, Volume 17, Issue 9, May 4, 2022., 2022 Hybrid power: New artemisinin‐ and synthetic peroxide‐based hybrids, highly active in vitro against leukemia cell lines and SARS‐CoV‐2, were synthesized. Remarkably, the most active anti‐cancer hybrid compounds are also the most potent and selective against SARS‐CoV‐2. Abstract The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐
Lars Herrmann +13 more
wiley +1 more source
Medicinal Research Reviews, Volume 41, Issue 6, Page 3023-3061, November 2021., 2021 Abstract The sesquiterpene lactone artemisinin from Artemisia annua L. is well established for malaria therapy, but its bioactivity spectrum is much broader. In this review, we give a comprehensive and timely overview of the literature regarding the immunosuppressive activity of artemisinin‐type compounds toward inflammatory and autoimmune diseases ...
Thomas Efferth, Franz Oesch
wiley +1 more source
Metal‐Coordinated Supramolecular Self‐Assemblies for Cancer Theranostics
Advanced Science, Volume 8, Issue 16, August 18, 2021., 2021 This review summarizes the recent progress made on metal‐coordinated supramolecular nanomedicines for cancer theranostic by classifying the coordination metal ions in the order of periodic table. Especially, the superiority of the tumor‐responsive nanomedicines for in vivo coordinated self‐assembling cancer theranostic is discussed, with an emphasis on
Jiating Xu +7 more
wiley +1 more source