Results 41 to 50 of about 997 (192)
Journal of the Serbian Chemical Society, 2009 The problem of endemic malaria continues unabated globally. Malaria affects 40 % of the global population, causing an estimated annual mortality of 1.5–2.7 million people.
DEJAN M. OPSENICA, BOGDAN A. ŠOLAJA
doaj +3 more sources
ChemMedChem, Volume 17, Issue 9, May 4, 2022., 2022 Hybrid power: New artemisinin‐ and synthetic peroxide‐based hybrids, highly active in vitro against leukemia cell lines and SARS‐CoV‐2, were synthesized. Remarkably, the most active anti‐cancer hybrid compounds are also the most potent and selective against SARS‐CoV‐2. Abstract The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐
Lars Herrmann +13 more
wiley +1 more source
Medicinal Research Reviews, Volume 41, Issue 6, Page 3023-3061, November 2021., 2021 Abstract The sesquiterpene lactone artemisinin from Artemisia annua L. is well established for malaria therapy, but its bioactivity spectrum is much broader. In this review, we give a comprehensive and timely overview of the literature regarding the immunosuppressive activity of artemisinin‐type compounds toward inflammatory and autoimmune diseases ...
Thomas Efferth, Franz Oesch
wiley +1 more source
Metal‐Coordinated Supramolecular Self‐Assemblies for Cancer Theranostics
Advanced Science, Volume 8, Issue 16, August 18, 2021., 2021 This review summarizes the recent progress made on metal‐coordinated supramolecular nanomedicines for cancer theranostic by classifying the coordination metal ions in the order of periodic table. Especially, the superiority of the tumor‐responsive nanomedicines for in vivo coordinated self‐assembling cancer theranostic is discussed, with an emphasis on
Jiating Xu +7 more
wiley +1 more source
Cyclic Organic Peroxides as New Fungicides against Phytopathogenic Fungi
Agrochemicals, 2023 The search for new classes of fungicides has long been important in plant protection due to the development of fungal resistance to currently used agrochemicals. Organic peroxides have long been regarded as exotic and unstable compounds. The discovery of
Ivan A. Yaremenko +8 more
doaj +1 more source
Small Science, Volume 1, Issue 3, March 2021., 2021 The preparation strategies of functional nucleic acid (FNA)‐decorated spherical nanoparticles (SNPs) are summarized with the focus on the current applications of aptamer‐, i‐motif‐, DNAzyme‐, antisense oligonucleotide (ASO)‐, and CpG oligodeoxynucleotide (ODN)‐decorated SNPs in cancer therapy, involved in targeted drug delivery, controlled drug release,
Min Zhu, Shan Wang
wiley +1 more source
, 2009 The problem of endemic malaria continues unabated globally. Malaria affects 40 % of the global population, causing an estimated annual mortality of 1.5-2.7 million people.
Opsenica, Dejan M., Šolaja, Bogdan A.
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Bioorganic & Medicinal Chemistry, 2018 A series of aryl carboxamide and benzylamino dispiro 1,2,4,5-tetraoxane analogues have been designed and synthesized in a short synthetic sequence from readily available starting materials. From this series of endoperoxides, molecules with in vitro IC50s versus Plasmodium falciparum (3D7) as low as 0.84 nM were identified.
Paul M. O' Neill +21 more
openalex +5 more sources
Diversification in the synthesis of antimalarial trioxane and tetraoxane analogs [PDF]
RSC Advances, 2014 AbstractReview: 180 refs.
Satish Kumar Awasthi +2 more
openaire +2 more sources
Thermal Decomposition of Diphenyl Tetroxane in Chlorobenzene Solution [PDF]
, 2019 The thermal decomposition of Cyclic Diperoxide of Benzaldehyde 3,6-diphenyl-1,2,4,5-tetroxane, (DFT) in chlorobenzene solution in the studied temperature range (130°C - 166°C) satisfactorily satisfies a first order law up to 60% conversions of diperoxide.
Bordón, Alexander Germán +6 more
core +1 more source