Results 41 to 50 of about 1,048 (196)
Small Science, Volume 1, Issue 3, March 2021., 2021 The preparation strategies of functional nucleic acid (FNA)‐decorated spherical nanoparticles (SNPs) are summarized with the focus on the current applications of aptamer‐, i‐motif‐, DNAzyme‐, antisense oligonucleotide (ASO)‐, and CpG oligodeoxynucleotide (ODN)‐decorated SNPs in cancer therapy, involved in targeted drug delivery, controlled drug release,
Min Zhu, Shan Wang
wiley +1 more source
Cyclic Organic Peroxides as New Fungicides against Phytopathogenic Fungi
Agrochemicals, 2023 The search for new classes of fungicides has long been important in plant protection due to the development of fungal resistance to currently used agrochemicals. Organic peroxides have long been regarded as exotic and unstable compounds. The discovery of
Ivan A. Yaremenko +8 more
doaj +1 more source
Synthesis and initial testing of novel antimalarial and antitubercular isonicotinohydrazides
Results in Chemistry, 2022 Malaria and tuberculosis (TB) though curable and preventable, remain serious public health problems globally, with devastating consequences. Co-infection of these two deadly diseases worsens the situation and particularly makes treatment very difficult ...
Richard K. Amewu +4 more
doaj +1 more source
, 2009 The problem of endemic malaria continues unabated globally. Malaria affects 40 % of the global population, causing an estimated annual mortality of 1.5-2.7 million people.
Opsenica, Dejan M., Šolaja, Bogdan A.
core +4 more sources
Steroidal Tetraoxanes - New Class of Antitumor Compounds
Proceedings of The 3rd International Electronic Conference on Synthetic Organic Chemistry, 1999 Cholic acid derived steroidal tetraoxanes possessing methyl ester, carboxylic acid, primary and secondary amide termini were synthesised and their in vitro antitumor activity against Fem-X and HeLa cell cultures was determined. IC50 range between 3.1 and 166 M. Five out of seven tested compounds exhibited cell rounding and / or apoptic activity.
Bogdan A. Šolaja +3 more
openalex +2 more sources
Thermal Decomposition of Diphenyl Tetroxane in Chlorobenzene Solution [PDF]
, 2019 The thermal decomposition of Cyclic Diperoxide of Benzaldehyde 3,6-diphenyl-1,2,4,5-tetroxane, (DFT) in chlorobenzene solution in the studied temperature range (130°C - 166°C) satisfactorily satisfies a first order law up to 60% conversions of diperoxide.
Bordón, Alexander Germán +6 more
core +1 more source
418 POSTER Investigation of some tetraoxanes as potential antitumour agents
, 2007 Željko Žižak +3 more
openalex +3 more sources
Bioorganic & Medicinal Chemistry, 2018 A series of aryl carboxamide and benzylamino dispiro 1,2,4,5-tetraoxane analogues have been designed and synthesized in a short synthetic sequence from readily available starting materials. From this series of endoperoxides, molecules with in vitro IC50s versus Plasmodium falciparum (3D7) as low as 0.84 nM were identified.
Paul M. O' Neill +21 more
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A Systematic Review of In vitro and In vivo Activities of Anti-Toxoplasma Drugs and Compounds (2006–2016) [PDF]
, 2017 The currently available anti-Toxoplasma agents have serious limitations. This systematic review was performed to evaluate drugs and new compounds used for the treatment of toxoplasmosis.
Ahmad Daryani +5 more
core +1 more source
BioMed Research International, Volume 2012, Issue 1, 2012., 2012 Improvement of quality of life and survival of cancer patients will be greatly enhanced by the development of highly effective drugs to selectively kill malignant cells. Artemisinin and its analogs are naturally occurring antimalarials which have shown potent anticancer activity.
Maria P. Crespo-Ortiz +2 more
wiley +1 more source