Results 71 to 80 of about 997 (192)

Examination of the cytotoxic and embryotoxic potential and underlying mechanisms of next-generation synthetic trioxolane and tetraoxane antimalarials [PDF]

, 2014
Semisynthetic artemisinin-based therapies are the first-line treatment for P. falciparum malaria, but next-generation synthetic drug candidates are urgently required to improve availability and respond to the emergence of artemisinin-resistant parasites.
Bringela, A., Chadwick, J., Copple, I. M., Cristiano, Maria Lurdes Santos, Donegan, G., Firman, J., Herpers, B., Mercer, A. E., O'Neill, Paul M., Park, B. K., Van De Water, B., Ward, Stephen A., Wong, M. H.   +12 more
core  

Metodologias de síntese de tetraoxanos com potencial utilização em química medicinal [PDF]

, 2015
Dissertação de Mestrado, Ciências Farmacêuticas, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 2015A malária é uma doença tropical infeciosa causada por parasitas do género Plasmodium, que são transmitidos pela picada de mosquitos ...
Amado, Patrícia
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Artefenomel Regioisomer RLA-3107 Is a Promising Lead for the Discovery of Next-Generation Endoperoxide Antimalarials. [PDF]

ACS Med Chem Lett, 2023
Blank BR, Gut J, Rosenthal PJ, Renslo AR.   +3 more
europepmc   +1 more source

Inducing oxidative stress in parasites: novel hybrid compounds based on peroxides to trap catalytic cysteine residues [PDF]

, 2017
Tese de mestrado, Química Farmacêutica e Terapêutica, Universidade de Lisboa, Faculdade de Farmácia, 2017Infectious diseases caused by viruses, parasites and bacteria are currently the second cause of mortality worldwide.
Coutinho, Daniela Sofia Ribeiro
core  

Differentiation between 1,2,4,5‐tetraoxanes and 1,2,4,5,7,8‐hexaoxonanes using ¹H and ¹³C NMR analyses [PDF]

, 2001
Yuxiang Dong, Jonathan L. Vennerstrom
openalex   +1 more source

Application of BF₃·Et₂O in the synthesis of cyclic organic peroxides (microreview). [PDF]

Chem Heterocycl Compd (N Y), 2020
Radulov PS, Yaremenko IA.
europepmc   +1 more source

Natural products and drug discovery. [PDF]

Natl Sci Rev, 2022
Newman DJ.
europepmc   +1 more source

The effect of some mixed tetraoxanes on germination and antioxidants in maize seedlings [PDF]

, 2018
Germination is one of the most sensitive phases in growth of agricultural plants, where optimal conditions in temperature and water accessibility are required.
Brankov, Milan, Dragičević, Vesna, Kravic, Natalija, Mesarović, Jelena, Milojković-Opsenica, Dušanka, Opsenica, Dejan, Simić, Milena   +6 more
core   +1 more source

Gene mining of immune microenvironment in hepatocellular carcinoma. [PDF]

Medicine (Baltimore), 2022
Xu ZW.
europepmc   +1 more source

Reactive Oxygen Species as the Brainbox in Malaria Treatment. [PDF]

Antioxidants (Basel), 2021
Egwu CO, Augereau JM, Reybier K, Benoit-Vical F.   +3 more
europepmc   +1 more source