Results 71 to 80 of about 1,048 (196)

An in vitro investigation into the anti-cancer potential of novel tetraoxane compounds for the treatment of chronic lymphocytic leukaemia / [PDF]

, 2018
This study aims to evaluate the therapeutic potential of five novel tetraoxane compounds and one novel tetraoxane-naphthalimide hybrid compound for chronic lymphocytic leukaemia.
O'Reilly, Alma
core  

Optimisation of the synthesis of second generation 1,2,4,5 tetraoxane antimalarials

Tetrahedron, 2016
Abstract An efficient route to the synthesis of potent antimalarial aryloxy 1,2,4,5-tetraoxanes is described that permits parallel synthesis for Structure–Activity Relationship (SAR) investigations. Brief details of the in vitro and in vivo antimalarial evaluation are included which enables identification of antimalarial leads for further development.
O' Neill, Paul M, Sabbani, Sunil, Nixon, Gemma L, Schnaderbeck, Matthew, Roberts, Natalie L, Shore, Emma R, Riley, Christopher, Murphy, Ben, McGillan, Paul, Ward, Stephen A, Davies, Jill, Amewu, Richard K   +11 more
openaire   +1 more source

Synthesis, Chemistry, Biological Evaluation And Structure-Activity Relationships Of Rac- And Chiral 6-Desmethyl-5Β –Hydroxy-D-Secoartemisinin And Analogs [PDF]

, 2017
The prevention and cure of malaria is difficult as it thrives under poor socio- and pharmacoeconomic conditions in third world, tropical and subtropical regions. It is a parasitic disease spread through the bite of an infected Anopheles mosquito.
Jihan, Mohamed Elsideiq
core   +1 more source

SYNTHESIS AND PHYTOTOXIC PROFILE OF A NEW TETRAOXANE DESIGNED FROM A COMMERCIAL AUXIN

, 2021
Isabel Valero Antolinez, Luiz C. A. Barbosa, Célia R. A. Maltha, Gustavo Antônio Mendes Pereira, A.A. Silva   +4 more
openalex   +1 more source

Supplementary data for article: Šegan, S. B.; Andrić, F.; Radoičić, A.; Opsenica, D. M.; Šolaja, B. A.; Zlatović, M.; Milojković-Opsenica, D. Correlation between Structure, Retention and Activity of Cholic Acid Derived Cis-Trans Isomeric Bis-Steroidal Tetraoxanes. Journal of Separation Science 2011, 34 (19), 2659–2667. https://doi.org/10.1002/jssc.201100185 [PDF]

, 2011
Supporting information for: [https://doi.org/10.1002/jssc.201100185]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789 ...
Andrić, Filip, Milojković-Opsenica, Dušanka, Opsenica, Dejan M., Radoičić, Aleksandra, Zlatović, Mario, Šegan, Sandra B., Šolaja, Bogdan A.   +6 more
core  

Artefenomel Regioisomer RLA-3107 Is a Promising Lead for the Discovery of Next-Generation Endoperoxide Antimalarials. [PDF]

ACS Med Chem Lett, 2023
Blank BR, Gut J, Rosenthal PJ, Renslo AR.   +3 more
europepmc   +1 more source

Application of BF₃·Et₂O in the synthesis of cyclic organic peroxides (microreview). [PDF]

Chem Heterocycl Compd (N Y), 2020
Radulov PS, Yaremenko IA.
europepmc   +1 more source

Natural products and drug discovery. [PDF]

Natl Sci Rev, 2022
Newman DJ.
europepmc   +1 more source

Catalytic performance and enantioselectivity of engineered oxidoreductases as biocatalysts [PDF]

, 2015
The thesis will evaluate the catalytic activity and enantioselectivity of native Old Yellow Enzyme from S.pastoranius in comparison with three engineered enzyme variants.
Petruzzi, Loric, Pfeifer, Marc
core  

Reactive Oxygen Species as the Brainbox in Malaria Treatment. [PDF]

Antioxidants (Basel), 2021
Egwu CO, Augereau JM, Reybier K, Benoit-Vical F.   +3 more
europepmc   +1 more source