Results 91 to 100 of about 5,827 (200)

Cyclin D mediates tolerance of genome-doubling in cancers with functional p53 [PDF]

, 2017
BACKGROUND: Aneuploidy and chromosomal instability (CIN) are common features of human malignancy that fuel genetic heterogeneity. Although tolerance to tetraploidization, an intermediate state that further exacerbates CIN, is frequently mediated by TP53 ...
Begum, J, Cerveira, J, Crockford, A, Cuomo, ME, Dewhurst, SM, Encheva, V, Grönroos, E, McGranahan, N, Patel, H, Purewal, S, Renshaw, MJ, Snijders, AP, Swanton, C, Zalmas, LP   +13 more
core  

Immunoglobulin Isotypes in Atlantic Salmon, Salmo Salar

Biomolecules, 2015
There are three major immunoglobulin (Ig) isotypes in salmonid fish: IgM, IgD and IgT, defined by the heavy chains μ, δ and τ, respectively. As a result of whole genome duplication in the ancestor of the salmonid fish family, Atlantic salmon (Salmo salar)
Ivar Hordvik
doaj   +1 more source

Polyploid superficial uroepithelial bladder barrier cells express features of cellular senescence across the lifespan and are insensitive to senolytics

Aging Cell, Volume 24, Issue 2, February 2025.
This study characterized umbrella cells, polyploid bladder uroepithelial barrier cells, as an example of potentially beneficial senescent cell present under normal physiology throughout the lifespan in mouse bladders. Bladder umbrella cells exhibit markers of tetraploidy‐induced senescence.
Iman M. Al‐Naggar, Maria Antony, Dylan Baker, Lichao Wang, Lucas Da Cunha Godoy, Chia‐Ling Kuo, Matthew O. Fraser, Phillip P. Smith, Ming Xu, George A. Kuchel   +9 more
wiley   +1 more source

Increasing the Conversion of Hyoscyamine to Scopolamine in Stable Autotetraploid Plants of Egyptian Henbane (Hyoscyamus muticus)

Journal of Medicinal Plants, 2012
Background : Ploidy manipulation is always accompanied by conspicuous changes in morphology and biochemical characteristics in plants. So that it is suggested as a rapid and useful strategy for breeding the quality and quantitative traits related to the ...
E Dehghan, E Ghotbi Ravandi, H Naghdi Badi, A Tanhaeian, B Hosseini Khalifani   +4 more
doaj  

Spatio‐Temporal Patterns of Hybridization in an Alloploid Salamander (Ambystomatidae: Ambystoma) and Conservation Implications of Introgression in a Unisexual Vertebrate

Ecology and Evolution, Volume 15, Issue 1, January 2025.
Here we investigate a gynogenetic allopolyploid triploid, the Silvery Salamander (LJJ—historically referred to as Ambystoma platineum), an asexual lineage. However, in our focal populations, neither parental species is present, and another sexual host, A. texanum (TT), is a required sperm donor.
Alessa V. Laserna, Christopher A. Phillips, Andrew R. Kuhns, Mark A. Davis, Joel B. Corush, Ken N. Paige   +5 more
wiley   +1 more source

Clonality contributes to the spread of Avrainvillea lacerata (Bryopsidales, Chlorophyta) in Hawai‘i

Journal of Phycology, Volume 60, Issue 6, Page 1371-1389, December 2024.
Abstract The relative rates of sexual versus asexual reproduction influence the partitioning of genetic diversity within and among populations. During range expansions, asexual reproduction often facilitates colonization and establishment. The arrival of the green alga Avrainvillea lacerata has caused shifts in habitat structure and community ...
Brinkley M. Thornton, Heather L. Spalding, Solenn Stoeckel, Melissa L. Harris, Rachael M. Wade, Stacy A. Krueger‐Hadfield   +5 more
wiley   +1 more source

Cytogenetical Studies in Two Tetraploid Mulberry Varieties (Moraceae) [PDF]

, 2013
Morus L. an economically important genus has more than 60 species distributed in both the Hemispheres. Chromosome number varies from 2n=28 to 2n=308 with ploidy level from x to 22x.
Munirajappa, ., Venkatesh, K.H.
core   +1 more source

Risk assessment of complex organoarsenic species in food

EFSA Journal, Volume 22, Issue 12, December 2024.
Abstract The European Commission asked EFSA for a risk assessment on complex organoarsenic species in food. They are typically found in marine foods and comprise mainly arsenobetaine (AsB), arsenosugars and arsenolipids. For AsB, no reference point (RP) could be derived because of insufficient toxicity data.
EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Agneta Åkesson, Vasileios Bampidis, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Gisela Degen, Antonio Hernández‐Jerez, Tim Hofer, Christer Hogstrand, Stefano Landi, Jean‐Charles Leblanc, Kyriaki Machera, Evangelia Ntzani, Guido Rychen, Salomon Sand, Katharina Vejdovszky, Barbara Viviani, Lars Barregård, Diane Benford, Eugenia Dogliotti, Kevin Francesconi, Jose Ángel Gómez Ruiz, Hans Steinkellner, Tanja Schwerdtle   +25 more
wiley   +1 more source

Polyploidy is widespread in Microsporidia

Microbiology Spectrum
Microsporidia are obligate intracellular eukaryotic parasites with an extremely broad host range. They have both economic and public health importance.
Amjad Khalaf, Mara K. N. Lawniczak, Mark L. Blaxter, Kamil S. Jaron   +3 more
doaj   +1 more source

The Medicago genome provides insight into the evolution of rhizobial symbioses [PDF]

Legumes (Fabaceae or Leguminosae) are unique among cultivated plants for their ability to carry out endosymbiotic nitrogen fixation with rhizobial bacteria, a process that takes place in a specialized structure known as the nodule.
Bisseling, T., Franken, C., Geurts, R., Hartog, M.V., Lang, C., Mitani, S.   +5 more
core   +2 more sources