Results 171 to 180 of about 5,827 (200)
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Canadian Journal of Research, 1946
Tetraploid forms of the flax variety, Redwing, and the F1 flax hybrid, Bison × Redwing, were most easily obtained by treatment of the epicotyl of seedlings with colchicine in lanolin emulsion. Seeds of the tetraploid forms were considerably larger than those of the diploid; but, because of their lower fertility and later maturity, yield and quality ...
J. W. Boyes, J. G. Ross
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Tetraploid forms of the flax variety, Redwing, and the F1 flax hybrid, Bison × Redwing, were most easily obtained by treatment of the epicotyl of seedlings with colchicine in lanolin emulsion. Seeds of the tetraploid forms were considerably larger than those of the diploid; but, because of their lower fertility and later maturity, yield and quality ...
J. W. Boyes, J. G. Ross
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Tetraploidy/near-tetraploidy acute myeloid leukemia
Leukemia Research, 2017A tetraploid/near tetraploid (T/NT) karyotype is a rare finding in acute myeloid leukemia (AML). Here we report 38 AML patients with a T/NT karyotype, including 26 men and 12 women with a median age of 65 years. T/NT karyotype was detected at initial diagnosis of AML in 16 patients, and acquired during the course of disease in 22 patients. All patients
Guilin Tang +10 more
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Prenatal Diagnosis of Tetraploidy
Fetal Diagnosis and Therapy, 1993A pregnancy was terminated at 24 weeks of amenorrhea when tetraploidy (92 XXXX) was diagnosed in fetal blood subsequent to ultrasonographic detection of a polymalformation syndrome. The severity of the neurological deficit in tetraploid infants and their death before 2 years of age require that prenatal diagnosis by cordocentesis be performed for ...
M.F. Nomballais +6 more
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Tetraploidy in BRCA2 breast tumours
European Journal of Cancer, 2012Tetraploidy and aneuploidy can be caused by cell division errors and are frequently observed in many human carcinomas. We have recently reported delayed cytokinesis in primary human fibroblasts from BRCA2 mutation carriers, implying a function for the BRCA2 tumour suppressor in completion of cell division.
Olafur A. Stefansson +5 more
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Neuropathology and Applied Neurobiology, 1977
Cells with tetraploid nuclei have been examined in the striate cortex of patients with visual impairment and compared with age and sex matched controls. The number of these nuclei is reduced in those with visual impairment suggesting that tetraploidy is dependent upon an intact visual pathway and may be related to visual experience and memory.
D. M. A. Mann, C. L. Scholtz
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Cells with tetraploid nuclei have been examined in the striate cortex of patients with visual impairment and compared with age and sex matched controls. The number of these nuclei is reduced in those with visual impairment suggesting that tetraploidy is dependent upon an intact visual pathway and may be related to visual experience and memory.
D. M. A. Mann, C. L. Scholtz
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A liveborn infant with tetraploidy
American Journal of Medical Genetics, 1988AbstractWe report on an 22‐month‐old white girl with tetraploidy who is growing well, but who is extremely delayed in psychomotor development. When counseling parents it is important to realize that, although quite rare, tetraploid individuals can be born alive and live for at least 22 moths. The implications are also relevant to prenatal diagnosis.
John M. Opitz +3 more
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Tetraploidy, aneuploidy and cancer
Current Opinion in Genetics & Development, 2007Aneuploidy is one of the most obvious differences between normal and cancer cells. However, there remains debate over how aneuploid cells arise and whether or not they are a cause or consequence of tumorigenesis. One proposed route to aneuploid cancer cells is through an unstable tetraploid intermediate. Supporting this idea, recent studies demonstrate
David Pellman +2 more
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Mosaic tetraploidy in a male neonate
Clinical Genetics, 1982Though complete and mosaic tetraploidy in zygotes almost always leads to abortion early in pregnancy, some cases have been described in which development was more successful. We report a male neonate with microcephaly and various other anomalies, in whom tetraploidy was found in 16% of peripheral lymphocytes.
E. W. K. Tasseron +2 more
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Tetraploidy and the striate cortex
Pathology, 1977A tetraploid population of glial cell nuclei has been identified in layers one, two and three of the entire striate cortex. These have approximately twice the volume of diploid glial cell nuclei.
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Nondisjunction, aneuploidy and tetraploidy
Nature, 2006One simple, widely accepted mechanism for generating an aberrant chromosome number, or aneuploidy, is through nondisjunction--a chromosome distribution error that occurs during mitosis when both copies of a duplicated chromosome are deposited into one daughter cell and none into the other.
Don W. Cleveland +2 more
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