Results 181 to 190 of about 5,827 (200)

Development of tetraploidy in V79 spheroids

In Vitro, 1982
Chinese hamster V-79-171 cells, when placed in suspension culture, spontaneously form multicell spheroids. As the spheroids enlarge the fraction of polyploid (predominantly tetraploid) cells increases and can approach 100% in very large spheroids. Spheroid size, rather than age, seems to be a major determinant for increased ploidy. When cell separation
R. E. Durand, J. C. Leonard, P. L. Olive
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Tetraploidy and the Evolution of Salmonid Fishes [PDF]

, 1984
Polyploidy has long been recognized to have played an important role in the evolution of plant species (Lewis, 1980). However, polyploidy has only recently been recognized as a potentially important process in the evolution of vertebrates (Ohno, 1974; Fisher et al.,1980; Bogart, 1980; Schultz, 1980).
Gary H. Thorgaard, Fred W. Allendorf
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G1 tetraploidy checkpoint and the suppression of tumorigenesis

Journal of Cellular Biochemistry, 2002
AbstractCheckpoints suppress improper cell cycle progression to ensure that cells maintain the integrity of their genome. During mitosis, a metaphase checkpoint requires the integration of all chromosomes into a metaphase array in the mitotic spindle prior to mitotic exit. Still, mitotic errors occur in mammalian cells with a relatively high frequency.
Robert L. Margolis, Olivier D. Lohez, Paul R. Andreassen   +2 more
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Tetraploidy inProtopterus (Dipnoi) [PDF]

Experientia, 1980
Comparative DNA values obtained by Feulgen cytophotometry for 3 species ofProtopterus, as well as karyotype analysis, show the existence of a diploid-tetraploid relationship within the genusProtopterus.
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The prognostic implications of tetraploidy/near-Tetraploidy in acute myeloid leukemia: a case series and systematic review of the literature

Leukemia & Lymphoma, 2020
The prognostic significance and optimal management of tetraploidy/near-tetraploidy acute myeloid leukemia (T/NT AML) remains unclear given its limited data. This is especially true after factoring in additional chromosomal alterations, which carry their own prognostic weight.
John Xie, Adeem Nachabe, Lindsey J. Hathaway, Bachir Farah, Bachir Berbari, Yuwen Li, Theresa C. Brown, Janet L. Schmid, Francisco Socola, Nakhle S. Saba, Hana Safah   +10 more
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In Vitro Tetraploidy in Patients with Ulcerative Colitis

Scandinavian Journal of Gastroenterology, 1987
One hundred and seven patients (57 patients with ulcerative colitis and 50 controls) were investigated for in vitro tetraploidy (IVT) in dermal fibroblast monolayer cultures. There was no difference in incidence of IVT between patients with ulcerative colitis and controls.
K Lauritsen, J. O. Hegnhøj, Steffen Bülow, Danes Bs, Højgård L, Thomas Horn, J. O. Søndergaard, Lars Bo Svendsen   +7 more
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Genetic algebras for tetraploidy with several loci

Journal of Mathematical Biology, 1980
The algebra of gamete multiplication corresponding to a population of autotetraploids which differ at n loci, each with an arbitrary number of alleles, is proven to be a genetic algebra, irrespective of the mode of segregation of the n loci.
Peter Fortini, Richard Barakat, Richard Barakat   +2 more
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Near-tetraploidy/tetraploidy acute myeloid leukemia with clinical, pathologic and molecular characteristics

Leukemia & Lymphoma
Near-tetraploidy/tetraploidy (NT/T) is a cytogenetic alteration in acute myeloid leukemia (AML). In AML, specific chromosomal alterations are associated with clinical, morphological, and immunophenotypic features. The impact of cytogenetics on the prognosis of AML is well established.
Jacob, Fang, Nakul, Shankar, Liming, Bao, Mary, Haag, Billie, Carstens, Changlee S, Pang   +5 more
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A brief look at the origin of tetraploidy

Cytogenetic and Genome Research, 2004
Bernd Rosenbusch, M. Schneider
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Tetraploidy and the Evolution of the Catostomid Fishes

1984
The catostomid fishes provide an excellent opportunity to follow the evolutionary fates of duplicate genes. The genomes of these fish are still in a state of flux owing to polyploidization some 50 million years ago. The time of origin of these fish is advantageous in understanding the overall picture of genome evolution in eukaryotes.
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