Results 41 to 50 of about 5,827 (200)
Journal of Developmental Biology, 2023 Whole genome duplication (WGD) or polyploidization can occur at the cellular, tissue, and organismal levels. At the cellular level, tetraploidization has been proposed as a driver of aneuploidy and genome instability and correlates strongly with cancer ...
Mara Schvarzstein +3 more
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Molecular biomarkers and ablative therapies for Barrett’s esophagus [PDF]
, 2012 Author version made available in accordance with the publisher's policy.Barrett’s esophagus is the major risk factor for esophageal adenocarcinoma. Endoscopic interventions which ablate Barrett’s esophagus mucosa lead to replacement with a new squamous ...
Chisolm, Jacob A +3 more
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Addressing a weakness of anticancer therapy with mitosis inhibitors: Mitotic slippage
Molecular & Cellular Oncology, 2017 Mitosis inhibitors, which include antimicrotubule drugs, are chemotherapy agents that induce the arrest and apoptosis of mitotic cells. Mitotic slippage, in which mitotically arrested cells exit mitosis, limits the effectiveness of mitosis inhibitors. We
Riju S. Balachandran, Edward T. Kipreos
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Journal of Biological Researches, 2012 The aim of this study were to know growth and gonadal development of tetraploidy common carp. The method that used in this study was experiment. Treatment that used was tetraploidyzation by heat shock 40 °C during 1.5 minutes of common carp eggs to 29 ...
Akhmad Taufiq Mukti
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100 Years of Chromosome Research in Rye, Secale L.
Plants, 2022 Although microscopy and genetics were still in their infancy, there are cytological results produced a hundred years ago that are still relevant today. Since the 1920s, rye has been a subject of chromosome research. It started by plotting its mitotic and
Rolf Schlegel
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Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition. [PDF]
, 2015 Cellular senescence is a widespread stress response and is widely considered to be an alternative cancer therapeutic goal. Unlike apoptosis, senescence is composed of a diverse set of subphenotypes, depending on which of its associated effector programs ...
Acosta JC +113 more
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Comparative cytogenetics of anembryonic pregnancies and missed abortions in human
Вавиловский журнал генетики и селекции, 2023 Miscarriage is an important problem in human reproduction, affecting 10–15 % of clinically recognized pregnancies. The cases of embryonic death can be divided into missed abortion (MA), for which the ultrasound sign of the embryo death is the absence of ...
T. V. Nikitina +5 more
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Intratumoral patterns of clonal evolution in gliomas [PDF]
, 2009 Few studies have explored the patterns of clonal evolution in gliomas. Here, we investigate the cytogenetic patterns of intratumoral clonal evolution of gliomas and their impact on tumor histopathology and patient survival.
Crespo, I +7 more
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Asymmetric clustering of centrosomes defines the early evolution of tetraploid cells
eLife, 2020 Tetraploidy has long been of interest to both cell and cancer biologists, partly because of its documented role in tumorigenesis. A common model proposes that the extra centrosomes that are typically acquired during tetraploidization are responsible for ...
Nicolaas C Baudoin +5 more
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Identification of the relationship between Chinese Adiantum reniforme var. sinense and Canary Adiantum reniforme [PDF]
, 2015 © 2014 Wang et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...
Chen, H-F +8 more
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