Results 51 to 60 of about 5,026 (197)

Identification of chromosomal abnormalities and genomic features in near-triploidy/tetraploidy-acute leukemia by fluorescence in situ hybridization

open access: yesCancer Management and Research, 2019
Ruqing Yang,1 Minghua Jiang,2 Junzhao Zhao,1 Hui Chen,2 Jian Gong,2 Yaying You,3 Laiyue Song,3 Zhen Li,4 Qian Li2 1Reproductive Medicine Center, Department of Gynaecology and Obstetrics, The Second Affiliated Hospital and Yuying Children’s Hospital
Yang R   +8 more
doaj  

Experimental Evolution Reveals Interplay between Sch9 and Polyploid Stability in Yeast. [PDF]

open access: yesPLoS Genetics, 2016
Polyploidization has crucial impacts on the evolution of different eukaryotic lineages including fungi, plants and animals. Recent genome data suggest that, for many polyploidization events, all duplicated chromosomes are maintained and genome ...
Yi-Jin Lu, Krishna B S Swamy, Jun-Yi Leu
doaj   +1 more source

Repeated Independent Formation of Triploid Lineages Contributes to Clonal Diversity in Heteronotia binoei Parthenogens

open access: yesMolecular Ecology, Volume 35, Issue 2, January 2026.
ABSTRACT Parthenogenesis, or all‐female clonal reproduction, is rare among vertebrates. This is often attributed to the selective disadvantages of assumed reduction of genetic diversity in the absence of sex. However, parthenogenetic vertebrates have highly complex evolutionary histories, with most arising through hybridisation and many being polyploid.
Kate E. O'Hara   +4 more
wiley   +1 more source

DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development. [PDF]

open access: yesPLoS ONE, 2010
During tumorigenesis, cells acquire immortality in association with the development of genomic instability. However, it is still elusive how genomic instability spontaneously generates during the process of tumorigenesis.
Yosuke Ichijima   +10 more
doaj   +1 more source

Benchmarking Ploidy Estimation Methods for Bulk and Single‐Cell Whole Genome Sequencing

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
It comprehensively benchmarks computational tools for ploidy estimation from bulk and single‐cell whole‐genome sequencing data. The results highlight the strengths and limitations of each method under different conditions and identify PURPLE and SeCNV show top performance in bulk and single‐cell settings, respectively.
Yawei Song   +8 more
wiley   +1 more source

CHROMOSOME NUMBERS OF CHILEAN PTERIDOPHYTES: FIRST CONTRIBUTION NUMEROS CROMOSOMICOS DE PTERIDOFITOS CHILENOS: PRIMERA CONTRIBUCION

open access: yesGayana: Botanica, 2006
Mitotic chromosome counts in Chilean pteridophytes confirm the diploidy described for Equisetum L. (2n = 216) and Blechnum L. (2n = 66), as well as the tetraploidy of Asplenium L. (2n = 144). Megalastrum spectabile (Kaulf.) A.R.Sm.
Pedro Jara-Seguel   +2 more
doaj  

Targeting RBM10‐Repressed RORB Activity in Liquid Condensates Inhibits Lysosomal Biogenesis and Neuroblastoma Progression via Affecting NF‐κB Signaling

open access: yesAdvanced Science, Volume 12, Issue 44, November 27, 2025.
This study identifies that RBM10 represses the transcriptional activity of RORB in liquid condensates, resulting in down‐regulation of NR1D1 and RIOK3 that further activates NF‐κB activity to facilitate lysosomal biogenesis and aggressive features of NB cells.
Yanhua Guo   +9 more
wiley   +1 more source

Immunoglobulin Isotypes in Atlantic Salmon, Salmo Salar

open access: yesBiomolecules, 2015
There are three major immunoglobulin (Ig) isotypes in salmonid fish: IgM, IgD and IgT, defined by the heavy chains μ, δ and τ, respectively. As a result of whole genome duplication in the ancestor of the salmonid fish family, Atlantic salmon (Salmo salar)
Ivar Hordvik
doaj   +1 more source

Effects of Ploidy on Relationship Between Outbreeding Response and Fitness in a Plant Selfing Species

open access: yesEcology and Evolution, Volume 15, Issue 11, November 2025.
Outbreeding response is both ploidy‐dependent and functionally tied to fitness, highlighting its potential role in promoting outcrossing and driving mating system evolution in inbred plant populations. ABSTRACT Outbreeding response, the phenotypic differences observed between selfed parental lines and their outcrossed offspring, can influence the ...
Carlos Olmedo‐Castellanos   +5 more
wiley   +1 more source

In Vitro Initiation, Regeneration, and Characterization of Plants Derived from Mature Tetraploid Floral Explants of Date Palm (Phoenix dactylifera L.)

open access: yesHorticulturae
A stable tetraploid date palm mutant with the potential for increased fruit size was recovered from a sectorial di-tetraploid chimera via the in vitro culture of flower explants.
Ahmed Othmani   +5 more
doaj   +1 more source

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