The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation
ABSTRACT Mutations in CCDC11 (cfap53) have been identified in multiple patients with heterotaxy (Htx), a disorder of left–right (LR) patterning of the internal organs. In Xenopus, depletion of Ccdc11 causes defects in LR patterning, recapitulating the patient phenotype. Upon Ccdc11 depletion, monociliated cells of the Left–Right Organizer (LRO) exhibit
Saurabh S. Kulkarni+9 more
wiley +1 more source
Evaluation of induced polyploidy in Acacia mearnsii through stomatal counts and guard cell measurements [PDF]
The black wattle, Acacia mearnsii, an important commercially grown tree in South Africa, is considered one of the top alien invader species within indigenous vegetation because of its abundant seed production and dispersal.
Beck, S.L.+3 more
core +1 more source
Selenium, selenoenzymes, oxidative stress and risk of neoplastic progression from Barrett's esophagus: results from biomarkers and genetic variants. [PDF]
Clinical trials have suggested a protective effect of selenium supplementation on the risk of esophageal cancer, which may be mediated through the antioxidant activity of selenoenzymes.
Yumie Takata+10 more
doaj +1 more source
Abstract The purpose of this study was to assess the additional contribution of karyotyping compared with genome‐wide non‐invasive prenatal testing (NIPT) for pregnancies at intermediate risk for trisomy 21 (T21), calculated using the maternal serum screening without major structural anomalies detected through sonography.
Gul Alkan Bulbul+6 more
wiley +1 more source
The characterisation of microsatellite markers reveals tetraploidy in the Greater Water Parsnip, Sium latifolium (Apiaceae). [PDF]
BACKGROUND: The Greater Water Parsnip, Sium latifolium (Apiaceae), is a marginal aquatic perennial currently endangered in England and consequently the focus of a number of conservation translocation projects. Microsatellite markers were developed for S.
A Rice+27 more
core +4 more sources
Fetal Corpus Callosum Anomalies
Anomalies of the corpus callosum (CC) are amongst the most common fetal Central Nervous System (CNS) anomalies detectable on ultrasound. Underlying genetic disease plays an important part in defining prognosis. Associations with aneuploidy and submicroscopic chromosomal deletions or duplications have been well demonstrated using chromosomal microarray ...
Valeria Lanzarone+2 more
wiley +1 more source
Colchicine-Induced Polyploidy in Rhododendron fortunei Lindl
Polyploidy in Rhododendron fortunei has great potential to improve its horticultural and commercial value, and to also meet market demands. In this study, a feasible method for polyploid induction in R.
Lan Mo+7 more
doaj +1 more source
No Evidence for Distinct Transcriptomic Subgroups of Devil Facial Tumor Disease (DFTD)
ABSTRACT Contagious cancers represent one of the least understood types of infections in wildlife. Devil Facial Tumor Disease (comprised of two different contagious cancers, DFT1 and DFT2) has led to an 80% decline in the Tasmanian devil (Sarcophilus harrisii ) population at the regional level since it was first observed in 1996. There are currently no
Cleopatra Petrohilos+5 more
wiley +1 more source
Isolation, molecular characterisation and mapping of four rose MLO orthologues
Powdery mildew is a major disease of economic importance in cut and pot roses. As an alternative to conventional resistance breeding strategies utilising single-dominant genes or QTLs, mildew resistance locus o (MLO)-based resistance might offer some ...
Helgard eKaufmann+3 more
doaj +1 more source
Reassessing Drought Tolerance in Citrus Tetraploid Rootstocks: Myth or Reality?
Abstract Polyploidy, particularly tetraploidy, has emerged as a promising tool in citrus rootstock breeding due to its potential to enhance drought tolerance. This review examines the role of tetraploid rootstocks in drought resilience, focusing on molecular and physiological adaptations observed in controlled environments and field conditions ...
Lucas da Silva Costa+5 more
wiley +1 more source