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Protolytic Equilibria in Tetrazoles

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
R. E. Trifonov, V. A. Ostrovskii
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Tetrazoles: XLV. Amidoalkylation of 5-Substituted Tetrazoles

Russian Journal of Organic Chemistry, 2003
Amidoalkylation of 5-aryl(hetaryl)tetrazoles with N-hydroxymethylamides of aliphatic and aromatic carboxylic acids occurs regioselectively and yields mainly 5-aryl(hetaryl)-2-acylaminomethyltetrazoles. These compounds arefairly stable in neutral media but are smoothly deprotected by the action of aqueous sodium hydroxide or hydrochloric acid.
L. V. Myznikov   +3 more
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Tetrazoles

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Tetrazoles: XLVII. A route to tetrazole-containing dendrimers

Russian Journal of Organic Chemistry, 2004
The reaction of 5-methylsulfonyl-1-phenyltetrazole with pentaerythritol in acetonitrile in the presence of sodium hydroxide gave tetrakis(1-phenyltetrazol-5-yloxymethyl)methane. Sulfur-containing analog of the latter was obtained by alkylation of 1-phenyl-4,5-dihydrotetrazole-5-thione with 1,3-dibromo-2,2-bis-(bromomethyl)propane.
T. V. Artamonova   +2 more
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Metal derivatives of tetrazoles

Russian Chemical Reviews, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
P. N. Gaponik   +2 more
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Synthesis of (difluoroamino)tetrazoles and [(difluoroamino)alkyl]tetrazoles

Russian Chemical Bulletin, 2000
(Difluoroamino)tetrazoles were obtained by direct fluorination of 5-aminotetrazoles with gaseous fluorine. Reactions of 2-(oxoalkyl)- and 2-(hydroxyalkyl)tetrazoles with difluoroamine yielded [(difluoroamino)alkyl]tetrazoles.
A. V. Fokin   +3 more
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Reactions of organotin tetrazoles: synthesis of functionalised poly-tetrazoles

Journal of the Chemical Society, Perkin Transactions 1, 1999
Reaction of 1,2-bis[2-(tributylstannyl)tetrazol-5-yl]benzene with 1,2-dibromoethane (1∶10) yields the 1-N,1-N′-ethylene bridged cyclophane (1) while similar reactions with larger excesses (1∶25) of 1,n-dibromoalkanes yield 1,2-bis[2-(bromoalkyl)tetrazol-5-yl]benzenes along with the unsymmetrical 1-N,2-N-substituted tetrazole isomers. Analogous products
Paul A. Bethel   +3 more
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Tetrazoles for biomedicine

Russian Chemical Reviews, 2019
The tetrazole ring is an important pharmacophore. It is a structural component in many drugs, drug candidates (or lead compounds) and various biochemical reagents.
Elena A. Popova   +2 more
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Tetrazoles: XLIX. Alkylation of tetrazoles with tetrakis(chloroacetoxymethyl)methane

Russian Journal of Organic Chemistry, 2006
Alkylation of 1-aryl-4,5-dihydro-1H-tetrazol-5-ones and 1-phenyl-4,5-dihydro-1H-tetrazole-5-thione with tetrakis(2-chloroacetoxymethyl)methane in boiling acetonitrile in the presence of potassium bromide and triethylamine gives tetrakis[2-(4-aryl-5-oxo-4,5-dihydro-1H-tetrazol-1-yl)acetoxymethyl]-methanes and tetrakis[2-(1-phenyl-1H-tetrazol-5 ...
M. V. Zatsepina   +2 more
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The Hydrogen Bond Environments of 1H-Tetrazole and Tetrazolate Rings: The Structural Basis for Tetrazole–Carboxylic Acid Bioisosterism

Journal of Chemical Information and Modeling, 2012
Bioisosterism involving replacement of a carboxylic acid substituent by 1H-tetrazole, yielding deprotonated carboxylate and tetrazolate under physiological conditions, is a well-known synthetic strategy in medicinal chemistry. To improve our overall understanding of bioisosterism, we have used this example to study the geometrical and energetic aspects
Frank H. Allen   +5 more
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