Results 1 to 10 of about 12,506 (227)

2-Methyl-3-{4-[2-(1H-tetrazol-5-yl)ethylamino]phenyl}-3H-quinazolin-4-one

Molbank, 2010
This present work aims at synthesizing a novel tetrazole from quinazolinone. 3-(4-Aminophenyl)-2-methyl-3H-quinazolin-4-one is converted into a nitrile by reacting it with acrylonitrile and triton B.
Helen P. Kavitha, Subramaniyan Arulmurugan   +1 more
doaj   +1 more source

Photochemical Synthesis of Pyrazolines from Tetrazoles in Flow

SynOpen, 2023
Pyrazolines and their pyrazole congeners are important heterocyclic building blocks with numerous applications in the fine chemical industries. However, traditional routes towards these entities are based on multistep syntheses generating substantial ...
Adam Burke, Silvia Spiccio, Mara Di Filippo, Marcus Baumann   +3 more
doaj   +1 more source

A review of recent developments in pharmaceutical chemistry on biological evolution of tetrazole derivatives

Al-SalamJournal for Medical Science
This review sums up the developments in the biological activity of tetrazole active derivatives in recent days. Some of the deliberated derivatives of tetrazole are at present actively scientifically studied; some of them have biological activity that ...
Zahraa A. Ketan, Halah A. R. Ibrahim, Dhuha K. Slma, Hind A. Satar, ASMAA A. JAWAD   +4 more
doaj   +1 more source

Towards Universal Stimuli-Responsive Drug Delivery Systems: Pillar[5]arenes Synthesis and Self-Assembly into Nanocontainers with Tetrazole Polymers

Nanomaterials, 2021
In this work, we have proposed a novel universal stimulus-sensitive nanosized polymer system based on decasubstituted macrocyclic structures—pillar[5]arenes and tetrazole-containing polymers.
Dmitriy N. Shurpik, Lyaysan I. Makhmutova, Konstantin S. Usachev, Daut R. Islamov, Olga A. Mostovaya, Anastasia A. Nazarova, Valeriy N. Kizhnyaev, Ivan I. Stoikov   +7 more
doaj   +1 more source

Synthesis and evaluation of antimicrobial activity of novel 1,3,4-oxadiazole derivatives

Orbital: The Electronic Journal of Chemistry, 2011
In attempt to find new pharmacologically active molecules, we report here the synthesis and in vitro antimicrobial activities of various novel 1,3,4-oxadiazole containing 5-phenyltetrazole.
Popat B. Mohite, V. H. Bhaskar
doaj   +1 more source

Scope of tetrazolo[1,5-a]quinoxalines in CuAAC reactions for the synthesis of triazoloquinoxalines, imidazoloquinoxalines, and rhenium complexes thereof

Beilstein Journal of Organic Chemistry, 2022
The conversion of tetrazolo[1,5-a]quinoxalines to 1,2,3-triazoloquinoxalines and triazoloimidazoquinoxalines under typical conditions of a CuAAC reaction has been investigated.
Laura Holzhauer, Chloé Liagre, Olaf Fuhr, Nicole Jung, Stefan Bräse   +4 more
doaj   +1 more source

Synthesis and antifungal activity of 3-aryl-1-(5-phenyl-1H-tetrazol-1-yl)prop-2-en-1-One

Orbital: The Electronic Journal of Chemistry, 2011
5-phenyl 1-acetyl tetrazole were allowed to react separately with different aromatic aldehydes in presence of alkaline medium to yield corresponding 5-phenyl tetrazole 1- substituted chalcones.The compounds were identified by spectral data and screened ...
Popat B. Mohite, Vaidhun H. Bhaskar
doaj   +1 more source

Combining the Ugi-azide multicomponent reaction and rhodium(III)-catalyzed annulation for the synthesis of tetrazole-isoquinolone/pyridone hybrids

Beilstein Journal of Organic Chemistry, 2019
An efficient sequence based on the Ugi-azide reaction and rhodium(III)-catalyzed intermolecular annulation has been established for the preparation of tetrazole-isoquinolone/pyridone hybrids.
Gerardo M. Ojeda, Prabhat Ranjan, Pavel Fedoseev, Lisandra Amable, Upendra K. Sharma, Daniel G. Rivera, Erik V. Van der Eycken   +6 more
doaj   +1 more source

Synthesis and physical-chemical properties of 6-(5-(1Н-tetrazole-1-ylmethyl)-4-R-1,2,4-triazole-3-ylthio)pyridin-3-amines and 6-((5-(1Н-tetrazole-1-yl)methil-4-R-1,2,4-triazole-3-ylthio)pyridin-3-yl)-(alk,ar,heter)ylmethanimines

Zaporožskij Medicinskij Žurnal, 2017
Over the past decade the number of publications, that contain different aspects of chemistry and use of triazoles and tetrazoles have been doubled and continues to grow. Puplications of recent years show that heterocycles with 1,2,3,4-teterazoles and 1,2,
Yu. S. Hulina, A. G. Kaplaushenko
doaj   +1 more source

Crystal structures of (Z)-5-[2-(benzo[b]thiophen-2-yl)-1-(3,5-dimethoxyphenyl)ethenyl]-1H-tetrazole and (Z)-5-[2-(benzo[b]thiophen-3-yl)-1-(3,4,5-trimethoxyphenyl)ethenyl]-1H-tetrazole

Acta Crystallographica Section E: Crystallographic Communications, 2016
(Z)-5-[2-(Benzo[b]thiophen-2-yl)-1-(3,5-dimethoxyphenyl)ethenyl]-1H-tetrazole methanol monosolvate, C19H16N4O2S·CH3OH, (I), was prepared by the reaction of (Z)-3-(benzo[b]thiophen-2-yl)-2-(3,5-dimethoxyphenyl)acrylonitrile with tributyltin azide via a [3 
Narsimha Reddy Penthala, Jaishankar K. B. Yadlapalli, Sean Parkin, Peter A. Crooks   +3 more
doaj   +1 more source