Results 1 to 10 of about 7,641 (139)

Exploring tetrazole chemistry: synthetic techniques, structure–activity relationship, and pharmacological insights in antimicrobial and anticancer therapy [PDF]

Frontiers in Chemistry
Tetrazoles are nitrogen-rich heterocycles that have attracted interest because of their numerous applications in pharmaceutical and medicinal chemistry.
Lalmohan Maji, Ghanshyam Teli, Ghanshyam Teli, Rohit Pal, Neelesh Maheshwari, Praveen Kumar Soni, Gurubasavaraja Swamy Purawarga Matada, Mahendra Singh Rathore, Venkatesan Saravanan, Kathiravan Muthukumaradoss   +9 more
doaj   +2 more sources

Development of fatty acid analogues with potent anabolic effects on bone in male mice [PDF]

Bone Reports
Natural fatty acids are inhibitory to osteoclastogenesis, but only mildly so, as reported earlier by our and other groups. To improve the potency, we have synthesized two categories of analogues based on the backbone of saturated palmitic acid by ...
Jian-ming Lin, Ivo Dimitrov, Karen E. Callon, Maureen Watson, Ian R. Reid, William A. Denny, Jillian Cornish   +6 more
doaj   +2 more sources

Synthesis of new multitope tetrazole-containing ligands

Журнал Белорусского государственного университета: Химия, 2022
Drawing the experience of 5-phenyl- and 5-pyridyltetrazoles, it was shown that classical nitration-reduction methods in combination with typical alkylation reactions of tetrazole derivatives can be used to obtain multitopic polynuclear tetrazole ...
Evgeny Y. Grigoriev, Ludmila S. Ivashkevich, Alexander S. Lyakhov, Inna M. Grigorieva, Yuri V. Grigoriev, Oleg A. Ivashkevich   +5 more
doaj   +1 more source

Synthesis and properties of tetrazole-containing polyelectrolytes based on chitosan, starch, and arabinogalactan

e-Polymers, 2022
The synthesis of tetrazole-containing derivatives of chitosan, starch, and arabinogalactan was carried out by a sequence of reactions including cyanoethylation of polysaccharides and subsequent azidation of cyanoethyl derivatives.
Pokatilov Fedor A., Akamova Helen V., Kizhnyaev Valery N.   +2 more
doaj   +1 more source

Synthesis of novel tetrazole tetrahydrobenzo[b]thiophene via Ugi-MCR: As new antileishmanial prototype

Journal of Saudi Chemical Society, 2021
A new series of tetrazole series of tetrazole tetrahydrobenzo[b]thiophene (10a-l) were synthesized and evaluated as antileishmanial activity and cytotoxicity of in vitro.
Sultan Pathan, Girdhar Pal Singh
doaj   +1 more source

Application of 1- and 2-propargyl-tetrazole in laser-ignitable energetic coordination compounds

FirePhysChem, 2023
1- and 2-Propargyl-tetrazole (1- and 2-PryTz) were synthesized by reaction of propargyl bromide with sodium tetrazolate and used as ligands in energetic coordination compounds (ECCs) and evaluated concerning their thermal and mechanical sensitivities ...
Simon M.J. Endraß, Thomas M. Klapötke, Jasmin T. Lechner, Jörg Stierstorfer   +3 more
doaj   +1 more source

Nitro-tetrazole based high performing explosives: Recent overview of synthesis and energetic properties

Defence Technology, 2021
Heterocyclic skeleton (Azoles) and different energetic groups containing high performing explosives are highly emerged in recent years to meet the challenging requirements of energetic materials in both military and civilian applications with improved ...
Saira Manzoor, Qamar-un-nisa Tariq, Xin Yin, Jian-Guo Zhang   +3 more
doaj   +1 more source

Investigation of the inhibition effect of 5-(3, 4, 5-Trimethoxyphenyl)-2H-tetrazole on mild steel corrosion in 1 M HCl solution [PDF]

شیمی کاربردی روز, 2020
In this work, the inhibition performance of 5-(3, 4, 5-Trimethoxyphenyl)-2H-tetrazole on mild steel corrosion was investigated in 1 M HCl solution. Scanning electron microscopy (SEM), electrochemical impedance spectroscopy(EIS) and polarization were used
Farshad Taghavi, Moosa Es'haghi
doaj   +1 more source

Synthesis, characterization and study of antibacterial activity of some novel tetrazole derivatives

Orbital: The Electronic Journal of Chemistry, 2011
This work aims at synthesizing novel tetrazole derivatives from phenothiazine. Phenothiazine is first converted into corresponding nitrile by reacting it with aldehyde, sodium metabisulphite and sodium cyanide.
Subramaniyan Arulmurugan, Helen P. Kavitha, Bathey R. Venkatraman   +2 more
doaj   +1 more source

Synthesis of 4-[10H-Phenothiazin-10-yl(1H-tetrazol-5-yl)-methyl]phenol

Molbank, 2009
This present work aims at synthesizing a novel tetrazole from phenothiazine. Phenothiazine is converted into a nitrile by reacting it with 4-hydroxybenzaldehyde, sodium metabisulphite and sodium cyanide. The nitrile on treatment with NaN3/DMF yielded the
Bathey R. Venkatraman, Helen P. Kavitha
doaj   +1 more source