Results 1 to 10 of about 196,937 (296)
Imidazoles as Potential Anticancer Agents: An Update on Recent Studies
Molecules, 2021 Nitrogen-containing heterocyclic rings are common structural components of marketed drugs. Among these heterocycles, imidazole/fused imidazole rings are present in a wide range of bioactive compounds.
Rajgopal Govindarajan, Karl A Werbovetz
exaly +3 more sources
Molecules, 2022 The acid dissociation constant of three benzimidazoles, namely 2,2′-bibenzo[d]imidazole, 2,5′-bibenzo[d]imidazole, and 5,5′-bibenzo[d]imidazole, have been investigated by means of density functional theory calculations in gas phase and in aqueous ...
Liudmil Antonov +2 more
doaj +1 more source
Review of pharmacological effects of imidazole derivatives [PDF]
Ķazaķstannyṇ Klinikalyķ Medicinasy, 2022 Imidazole derivatives are the perspective class of drugs with a broad spectrum of application in medicine. Imidazole is a nitrogen-containing heterocyclic ring; it has two equivalent forms; hydrogen atom may be located on any of two nitrogen atoms ...
Daniya Serdaliyeva +5 more
doaj +1 more source
SN Applied Sciences, 2021 In this paper, four novel kinds of triazine-trione based tri-imidazole derivatives (IM-TT, 2MI-TT, 2EI-TT and EMI-TT) were synthesized through the addition reaction between triglycidyl isocyanurate (TGIC) and imidazole (IM), 2-methylimidazole (2MI), 2 ...
Xiaodong Wan +3 more
doaj +1 more source
Molecules, 2023 Imidazole was first synthesized by Heinrich Debus in 1858 and was obtained by the reaction of glyoxal and formaldehyde in ammonia, initially called glyoxaline.
Heber Victor Tolomeu +1 more
doaj +1 more source
Aggregate, 2022 The development and enrichment of high‐performance organic fluorophores that simultaneously possess thermally activated delayed fluorescence (TADF) and aggregation‐induced emission (AIE) properties is going pursued but remains a great challenge due to ...
Ge Yang +5 more
doaj +1 more source
Mechanism of imidazole inhibition of a GH1 β‐glucosidase
FEBS Open Bio, 2023 Imidazole is largely employed in recombinant protein purification, including GH1 β‐glucosidases, but its effect on the enzyme activity is rarely taken into consideration.
Rafael S. Chagas +4 more
doaj +1 more source
Chemistry Proceedings, 2021 Imidazole derivatives are known for their varied biological applications, such as antibacterial, antifungal, antioxidant, antiviral, antiparasitic and anticancer compounds, among others. Therefore, numerous imidazole derivatives have been synthesized and
Nuna L. P. Ramos +3 more
doaj +1 more source
Current Research in Green and Sustainable Chemistry, 2021 The naturally occurring five-member imidazole derivatives have shown interesting biological as well as physiochemical properties and consequently they have found several chemicals, optical, pharmaceutical, and other useful biological applications.
Geetika Patel +3 more
doaj +1 more source
Chemistry Proceedings, 2021 2,4,5-Trisubstituted imidazole derivatives with heteroaromatic groups are versatile heterocyclic compounds exhibiting a wide range of biological activities, as well as very interesting thermal, optical, electronic, and redox properties.
Odília M. P. F. Luís +3 more
doaj +1 more source