Targeted Derepression of the Human Immunodeficiency Virus Type 1 Long Terminal Repeat by Pyrrole-Imidazole Polyamides [PDF]
, 2002 The host factor LSF represses the human immunodeficiency virus type 1 long terminal repeat (LTR) by mediating recruitment of histone deacetylase. We show that pyrrole-imidazole polyamides targeted to the LTR can specifically block LSF binding both in ...
Coull, Jason J. +5 more
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Polyimidazoles via aromatic nucleophilic displacement [PDF]
, 1991 Polyimidazoles (PI) are prepared by the aromatic nucleophilic displacement reaction of di(hydroxyphenyl) imidazole monomers with activated aromatic dihalides or activated aromatic dinitro compounds. The reactions are carried out in polar aprotic solvents
Connell, John W., Hergenrother, Paul M.
core +2 more sources
Structural and chemical requirements for histidine phosphorylation by the chemotaxis kinase CheA [PDF]
, 2005 The CheA histidine kinase initiates the signal transduction pathway of bacterial chemotaxis by autophosphorylating a conserved histidine on its phosphotransferase domain (P1).
Bilwes, Alexandrine M. +6 more
core +1 more source
Entropy, 2021 A multi-technique approach based on Knudsen effusion mass spectrometry, gas phase chromatography, mass spectrometry, NMR and IR spectroscopy, thermal analysis, and quantum-chemical calculations was used to study the evaporation of 1-butyl-3 ...
Anatoliy M. Dunaev +2 more
doaj +1 more source
Thiacalix[4]arene derivatives bearing imidazole units : a ditopic hard/soft receptor for Na⁺ and K⁺/Ag⁺ with an allosteric effect and a reusable extractant for dichromate anions [PDF]
, 2016 © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Two novel receptors 5,11,17,23-tetra-tert-butyl-25,27-bis[(ethoxycarbonyl)methoxy]-26,28-bis-[1-methyl-(imidazole)meth-oxy] -2,8,14,20-tetra-thiacalix[4]arene (L1) and 5,11,17,23-tetra-tert-butyl-25,27 ...
Akgemci +40 more
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Synthesis and Biological Evaluation of Novel Imidazole Derivatives as Antimicrobial Agents
BiomoleculesImidazole derivatives are considered potential chemical compounds that could be therapeutically effective against several harmful pathogenic microbes.
Huda A. Al-Ghamdi +8 more
doaj +1 more source
Paenidigyamycin G: 1-Acetyl-2,4-dimethyl-3-phenethyl-1H-imidazol-3-ium
Molbank, 2019 The Ghanaian Paenibacillus sp. DE2SH (GenBank Accession Number: MH091697) is a prolific producer of potent antiparasitic alkaloids. Further detailed study of the culture broth of this strain produced the compound Paenidigyamycin G (1), which is a ...
Gilbert Mawuli Tetevi +10 more
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Synthesis of some new series of Mannich base derivatives and their antimicrobial activity
Orbital: The Electronic Journal of Chemistry, 2011 A series of 1-[(4-substituted phenyl)(hydrazinyl)methyl]-1H-imidazole (1-6) were synthesized by Mannich reaction. Synthesized compounds 1-6 were confirmed by IR, ¹H NMR, ¹³C NMR, Mass and elemental analysis.
Radha Krishnan Surendra Kumar +2 more
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Surface Mutation Thr34His Facilitates Purification of Haemophilus influenza Carbonic Anhydrase via Metal Affinity Chromatography [PDF]
, 2017 In order to pursue Haemophilus influenza carbonic anhydrase (HICA) as a potential drug target, easy and efficient purification methods must be developed. While immobilized metal affinity chromatography (IMAC) may be used, complications with polyhistidine
Cornely, Dr. Kathleen, Foley, Caroline
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Frontiers in Chemistry, 2022 An efficient atom-economical synthetic protocol to access new imidazole-based N-phenylbenzamide derivatives is described. A one-pot three-component reaction was utilized to provide a series of N-phenylbenzamide derivatives in a short reaction time (2–4 h)
M. Shaheer Malik +15 more
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