Results 61 to 70 of about 196,937 (296)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Antitumor Activity of Pt(II), Ru(III) and Cu(II) Complexes

open access: yesMolecules, 2020
Metal complexes are currently potential therapeutic compounds. The acquisition of resistance by cancer cells or the effective elimination of cancer-affected cells necessitates a constant search for chemical compounds with specific biological activities ...
Katarzyna Gałczyńska   +2 more
doaj   +1 more source

Theoretical study on the mechanism of the cycloaddition reaction between ketenimine and hydrogen cyanide [PDF]

open access: yesJournal of the Serbian Chemical Society, 2016
The cycloaddition reaction mechanism between interstellar molecules ketenimine and HCN has been investigated employing the second-order Møller-Plesset perturbation theory (MP2) method in order to better understand the reactivity of nitrogenous ...
He Wenxing   +3 more
doaj   +1 more source

Synthesis, Characterization and Biological Evaluation of Novel Tetrasubsituted Imidazole Compounds [PDF]

open access: yes, 2020
A new class of tetrasubsituted imidazole based compounds were synthesized using multicomponent one pot synthesis scheme through cyclocondensation reaction of benzil, aromatic primary amines, aldehydes and ammonium acetate in glacial acetic acid.
khurram, shahzad   +5 more
core   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

open access: yesFEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi   +6 more
wiley   +1 more source

Reactivation of Serratia marcescens Endonuclease NucSma(H89G) by Hydroxilamine [PDF]

open access: yesУчёные записки Казанского университета: Серия Естественные науки, 2017
Serratia marcescens endonuclease is the most nonspecific nuclease known. This nuclease refers to enzymes that can cleave both DNA and RNA. The active site of this enzyme is characterized by the H–N–H motif, but more important functions have been shown ...
R.G. Khamidullina   +2 more
doaj  

Conformational Switching of Proteins on Material Surfaces Enabled by Peptide‐Oriented Adsorption

open access: yesAdvanced Functional Materials, EarlyView.
Responsive biointerfaces could be achieved using conformationally responsive proteins; however, their interconversion can be lost upon surface adsorption. Herein, we demonstrate that the incorporation a Au binding peptide into calmodulin allows for binding control on Au wherein the protein retains conformational switching. This capability was confirmed
Sakthirupini Ramamurthy   +7 more
wiley   +1 more source

A Handy and Solventless Direct Route to Primary 3-[3-Aryl)-1,2,4-oxadiazol-5-yl]propionamides Using Microwave Irradiation

open access: yesMolecules, 2006
A one-step, simple and straightforward synthesis of the title amides from the corresponding carboxylic acids, urea and imidazole under microwave irradiation is described.
Rajendra M. Srivastava   +1 more
doaj   +1 more source

4-Phenyl-1H-imidazole (a low-temperature redetermination), 1-benzyl-1H-imidazole and 1-mesityl-1H-imidazole

open access: yes, 2004
Low-temperature studies of the simple variously substituted imidazole types 4-phenyl-1H-imidazole, C9H8N2, 1-benzyl-1H-imidazole, C10H10N2, and 1-mesityl-1H-imidazole, C12H14N2, extend comparisons between parent imidazole species and their derivatives ...
Nielsen, DJ (15490025)   +3 more
core  

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