Reactivation of Serratia marcescens Endonuclease NucSma(H89G) by Hydroxilamine [PDF]
Serratia marcescens endonuclease is the most nonspecific nuclease known. This nuclease refers to enzymes that can cleave both DNA and RNA. The active site of this enzyme is characterized by the H–N–H motif, but more important functions have been shown ...
R.G. Khamidullina +2 more
doaj
Enhancing the cellular uptake of Py–Im polyamides through next-generation aryl turns [PDF]
Pyrrole–imidazole (Py–Im) hairpin polyamides are a class of programmable, sequence-specific DNA binding oligomers capable of disrupting protein–DNA interactions and modulating gene expression in living cells.
Baird +54 more
core +2 more sources
A one-step, simple and straightforward synthesis of the title amides from the corresponding carboxylic acids, urea and imidazole under microwave irradiation is described.
Rajendra M. Srivastava +1 more
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Site-specific incorporation of phosphotyrosine using an expanded genetic code. [PDF]
Access to phosphoproteins with stoichiometric and site-specific phosphorylation status is key to understanding the role of protein phosphorylation.
Allison Wong +36 more
core +1 more source
Activation of the Cyano Group at Imidazole via Copper Stimulated Alcoholysis
Reactions of 4,5-dicyano-1-methylimidazole with CuX2 (X = Cl, Br) in alcohol solvents (ethanol and methanol) resulted in the formation of Cu(II) carboximidate complexes [CuCl2(5- cyano-4-C(OEt)N-1-methylimidazole)(EtOH)] (1), [Cu2(µ-Cl)2Cl2(5-cyano ...
Rezeda Gayfullina +3 more
doaj +1 more source
Charge-Transfer Matrix Elements by FMO-LCMO Approach: Hole Transfer in DNA with Parameter Tuned Range-Separated DFT [PDF]
A scheme for computing charge-transfer matrix elements with the linear combination of fragment molecular orbitals and the 'nonempirically tuned range-separated' density functional is presented.
Ando, Koji, Kitoh-Nishioka, Hirotaka
core +2 more sources
2-(2-Hydroxy-5-methyl-3-formylphenyl)-imidazo[4,5-f][1,10]-phenanthroline
n ...
Liang-Nian Ji +3 more
doaj +1 more source
1-Benzyl-2-benzylsulfanyl-4,4-diphenyl-4,5-dihydro-1H-imidazol-5-one
The asymmetric unit of the title compound, C29H24N2OS, consists of two independent molecules having markedly different orientations of the substituents on the central imidazole ring.
Rachida Akrad +5 more
doaj +1 more source
Oligoglyceric acid synthesis by autocondensation of glyceroyl thioester [PDF]
The autocondensation of the glyceroyl thioester, S-glyceroyl-ethane-thiol, yielded olioglyceric acid. The rates of autocondensation and hydrolysis of the thioester increased from pH 6.5 to pH 7.5 in 2,6-lutidine and imidazole buffers.
Weber, A. L.
core +1 more source
Proton transfer in histidine-tryptophan heterodimers embedded in helium droplets
We used cold helium droplets as nano-scale reactors to form and ionize, by electron bombardment and charge transfer, aromatic amino acid heterodimers of histidine with tryptophan, methyl-tryptophan, and indole. The molecular interaction occurring through
Bellina, Bruno +2 more
core +1 more source

