Results 1 to 10 of about 35,659 (254)
Review- biological active benzimidazole derivatives
Results in Chemistry, 2021 In the field of Medicinal Chemistry, the uses of heterocyclic compounds increased day by day, because in many biological materials, heterocyclic compound is a part of its structure.
Balasaheb Pathare, Tanaji Bansode
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Synthesis and Bioactivity Studies of Benzimidazole-Chalcone Hybrids. [PDF]
MoleculesChalcones featuring α,β–unsaturated carbonyl group are associated with an extensive range of pharmacological properties. The synthesized derivatives of benzimidazole–chalcone are prominent classes of bioactive compounds that have demonstrated significant
Makgoathana HD +4 more
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Results in Chemistry, 2023 Heterocyclic compounds are foundational in drug discovery, constituting the core structure of approximately 80% of pharmaceuticals. Benzimidazole, in particular, emerges as a critical aromatic heterocyclic system present in natural compounds, playing an ...
Santosh J Uke
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Journal of Advanced Research, 2017 The aim of this present study was to synthesize 2-substituted and 1,2-disubstituted benzimidazole derivatives to investigate their antibacterial diversity for possible future drug design.
Yuxia Zhao +2 more
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Acta Pharmaceutica Sinica B, 2023 Cancer is the second leading cause of mortality globally which remains a continuing threat to human health today. Drug insensitivity and resistance are critical hurdles in cancer treatment; therefore, the development of new entities targeting malignant ...
Yeuan Ting Lee +2 more
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Benzimidazole-Quinoline Hybrids: Synthesis and Antimicrobial Properties. [PDF]
Pharmaceuticals (Basel)Background: Heterocyclic compounds are particularly important in medicinal chemistry. With a range of therapeutic uses, benzimidazoles and quinolines are both key heterocycles in medicinal chemistry.
Marinescu M.
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Monitoring of Benzimidazole Resistance in Botrytis cinerea Isolates from Strawberry in Korea and Development of Detection Method for Benzimidazole Resistance [PDF]
The Plant Pathology Journal, 2023 Botrytis cinerea is a major fungal plant pathogen that causes gray mold disease in strawberries, leading to a decrease in strawberry yield. While benzimidazole is widely used as a fungicide for controlling this disease, the increasing prevalence of ...
Geonwoo Kim +5 more
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Synthesis of ruthenium(II) carbonyl complexes with 2-monosubstituted and 1,2-disubstituted benzimidazoles [PDF]
Journal of the Serbian Chemical Society, 2009 The reaction of the polymeric carbonyl complex [RuCl2(CO)2]x with 2-monosubstituted and 1,2-disubstituted benzimidazoles and 1,4-bis(benzimi-dazol-2-yl)benzene (L9) in 2-methoxyethanol produces various coloured complexes of the formulae [Ru(CO)2Cl2(L)2 ...
GANGA NAIK KRISHNAMURTHY +1 more
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Synthesis and crystal structures of N-H, N-phenyl and N-benzyl-2-(4-hexyloxyphenyl)benzimidazoles
Acta Crystallographica Section E: Crystallographic Communications, 2021 The title compounds, 2-(4-hexyloxyphenyl)-1H-benzimidazole (C19H22N2O; 1), 2-(4-hexyloxyphenyl)-1-phenyl-1H-benzimidazole (C25H26N2O; 2) and 1-benzyl-2-(4-hexyloxyphenyl)-1H-benzimidazole (C26H28N2O; 3) were synthesized and their structures were ...
Daniil E. Smirnov +2 more
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Coumarin – benzimidazole hybrids: A review on diverse synthetic strategies
Results in Chemistry, 2022 Benzimidazole and coumarin are highly significant pharmacophores in medicinal chemistry due to their numerous and compelling biological activities. It has been found that combining two or more pharmacophores in a single moiety can improve the efficiency ...
C.G. Arya +6 more
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