Results 31 to 40 of about 37,139 (276)

Antibacterial Activity of the Halogen- and Nitro Derivatives of Benzimidazole Against Bacillus Subtilis

Антибиотики и Химиотерапия, 2023
Background. Antibiotic resistance of bacteria is a serious concern for modern medicine. The search for new compounds with a pronounced antibacterial effect is an urgent task of pharmaceutical chemistry.
R. S. Begunov, D. O. Egorov, A. V. Chetvertakova, L. I. Savina, A. A. Zubishina   +4 more
doaj   +1 more source

Preparation and properties of 1-methyl-1H-benzimidazole-based mesogenic compounds incorporating ethynyl moiety

, 2020
Heterocyclic mesogenic compounds are one of the interesting liquid crystals. Here, a series of 1-methyl-1H- benzimidazole-based mesogenic compounds incorporating ethynyl moiety, 2-[4-[2-[4-(alkoxy)phenyl]ethynyl]phenyl]-1-methyl-1H-1,3-benzimidazole ...
Shenghua Du (8262237), Pei Chen (252989), Mengting Zhang (753780), Xinbing Chen (810221), Jiazhen Dang (8262234), Aiai Gao (2610688), Zhongwei An (810222), Liyuan Ren (3862429), Weisong Du (2610685)   +8 more
core   +1 more source

Structure-based design of functionalized 2-substituted and 1,2-disubstituted benzimidazole derivatives and their in vitro antibacterial efficacy

Journal of Advanced Research, 2017
The aim of this present study was to synthesize 2-substituted and 1,2-disubstituted benzimidazole derivatives to investigate their antibacterial diversity for possible future drug design.
Olayinka O. Ajani, Olayinka O. Tolu-Bolaji, Shade J. Olorunshola, Yuxia Zhao, Damilola V. Aderohunmu   +4 more
doaj   +1 more source

New Perspectives in Therapy of Intoxications by Organophosphoric Compounds

Eurasian Chemico-Technological Journal, 2003
Little references actually exist on neutralization therapy which could constitute the missing ring from an efficient treatment. As structural model capable to interact with organophosphoric substances, at the level of phosphor (P) atom, the common ...
V. Sunel, M. Popa, C. L. Dumitriu, O. Pintilie   +3 more
doaj   +1 more source

Reaction of pyrido[1,2-a]benzimidazole and tetrahydropyrido[1,2-a]benzimidazole with acetylenedicarboxylic ester

, 2020
Previously unknown polynuclear condensed systems with bridgehead nitrogen atoms have been obtained by treating acetylenedicarboxylic ester with pyrido[1,2-a]-benzimidazole and tetrahydropyrido[1,2-a]benzimidazole.
Shendrik I.V., Prostakov N.S., Varlamov A.V., Golovtsov N.I., Krapivko A.P.   +4 more
core   +2 more sources

A Comprehensive Account on Recent Progress in Pharmacological Activities of Benzimidazole Derivatives

Frontiers in Pharmacology, 2021
Nowadays, nitrogenous heterocyclic molecules have attracted a great deal of interest among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole scaffolds are considerably prevalent.
Shejuti Rahman Brishty, Md. Jamal Hossain, Mayeen Uddin Khandaker, Mohammad Rashed Iqbal Faruque, Hamid Osman, S. M. Abdur Rahman   +5 more
doaj   +1 more source

Data on the effects of imidazo[1,2-a]benzimidazole and pyrimido[1,2-a]benzimidazole compounds on intraocular pressure of ocular normotensive rats

Data in Brief, 2018
This data is to document the intraocular pressure (IOP) lowering activity of imidazo[1,2-a]benzimidazole and pyrimido[1,2-a]benzimidazole compounds in ocular normotensive rats.
Adrian Julian Marcus, Igor Iezhitsa, Renu Agarwal, Pavel Vassiliev, Alexander Spasov, Olga Zhukovskaya, Vera Anisimova, Nafeeza Mohd Ismail   +7 more
doaj   +1 more source

Investigation of antioxidant activity of some bis-benzimidazole in Tetrahymena thermophila stressed cells [PDF]

, 2021
In this paper, we present experimental findings on the protective effect of some bis-benzimidazole molecules against oxidative (H2O2) and nitrosative (SNP) stress using the protozoan T. thermophila as a cellular model.
KNOUZI, Noureddine, ADDOUM, Boutaina, SOUKRI, Abdelaziz, OUAKET, Amine, EL KHALFI, Bouchra, BERRADA, Mohamed   +5 more
core   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

Second‐Sphere Aromatic Substitutions That Tune H‐Atom Transfer Reactivity Observed for a Series of S = 1 Nonheme FeIV=O Complexes: An Enthalpy‐Entropy Compensation Effect

Angewandte Chemie, EarlyView.
A series of oxoiron(IV) complexes was synthesized to determine the impact of electronically tuned aromatic substitution in the secondary sphere of the ligand. Despite possessing identical electronic properties, they show significant differences in C─H oxidation reactions.
Abhishek Das, Jin Xiong, Victor G. Young Jr., Yisong Guo, Marcel Swart, Lawrence Que Jr.   +5 more
wiley   +2 more sources