Results 1 to 10 of about 26,682 (264)

Activity of benzimidazoles against Dientamoeba fragilis (Trichomonadida, Monocercomonadidae) in vitro and correlation of beta-tubulin sequences as an indicator of resistance [PDF]

open access: yesParasite, 2014
Recently, Dientamoeba fragilis has emerged as a significant and common enteropathogen. The majority of patients with dientamoebiasis present with gastrointestinal complaints and chronic symptoms are common. Numerous studies have successfully demonstrated
Stark Damien   +5 more
doaj   +2 more sources

Facile, novel two-step syntheses of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines [PDF]

open access: yesMolecular Diversity, 2012
Three scaffolds of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines were synthesized via Ugi/de-protection/cyclization methodology. Benzimidazole forming ring closure was enabled under microwave irradiation in the presence of 10% TFA/DCE.
Zhigang, Xu   +5 more
openaire   +4 more sources

The mutagenicity of benzimidazole and benzimidazole derivatives III . The influence of the 2-substituent in benzimidazole on the mutagenic activity

open access: yesCHIMIA, 1973
A number of 2-substituted benzimidazoles has been prepared and the compounds were characterized by their physico-chemical and spectral properties. - Mutagenicity tests with two strains of Salmonella typhimurium revealed that on one hand the mutagenic ...
J.P. Seiler, H. Limacher
doaj   +2 more sources

Bis(benzimidazole) Complexes, Synthesis and Their Biological Properties: A Perspective

open access: yesInorganics, 2023
Benzimidazoles are a very well-known, broad group of compounds containing nitrogen atoms in their structure that can mimic properties of DNA bases. The compounds show not only biological activities but also are used for spectral and catalytic properties.
Zdeněk Šindelář, Pavel Kopel
doaj   +1 more source

Synthesis and Antimycobacterial Activity of 2,5-Disubstituted and 1,2,5-Trisubstituted Benzimidazoles

open access: yesFrontiers in Chemistry, 2020
The appearance of drug-resistant strains of Mycobacterium tuberculosis and the dramatic increase in infection rates worldwide evidences the urgency of developing new and effective compounds for treating tuberculosis. Benzimidazoles represent one possible
Rogelio Jiménez-Juárez   +11 more
doaj   +1 more source

Iron-Catalyzed Acceptorless Dehydrogenative Coupling of Alcohols With Aromatic Diamines: Selective Synthesis of 1,2-Disubstituted Benzimidazoles

open access: yesFrontiers in Chemistry, 2020
Benzimidazoles are important N-heteroaromatic compounds with various biological activities and pharmacological applications. Herein, we present the first iron-catalyzed selective synthesis of 1,2-disubstituted benzimidazoles via acceptorless ...
Ramachandra Reddy Putta   +8 more
doaj   +1 more source

Unexpected Synthesis, Single-Crystal X-ray Structure, Anticancer Activity, and Molecular Docking Studies of Certain 2–((Imidazole/Benzimidazol–2–yl)thio)–1–arylethanones

open access: yesCrystals, 2020
In connection with our research program concerning development of novel effective benzimidazole-based anticancer candidates, herein we describe a new unexpected synthetic route to obtain a series of 2–((imidazole/benzimidazol2–yl)thio)1–arylethanones ...
Tarfah Al-Warhi   +7 more
doaj   +1 more source

Peroxide impact on the fate of veterinary drugs in fertilizers [PDF]

open access: yes, 2020
The presence of veterinary medicines in organic manure causes soil contamination which contributes to increasing resistance of indigenous microflora to drugs and results in greater susceptibility of people to allergies.
Kalka, Joanna   +3 more
core   +1 more source

Advances in the Synthesis of Ring-Fused Benzimidazoles and Imidazobenzimidazoles

open access: yesMolecules, 2021
This review article provides a perspective on the synthesis of alicyclic and heterocyclic ring-fused benzimidazoles, imidazo[4,5-f]benzimidazoles, and imidazo[5,4-f]benzimidazoles.
Martin Sweeney   +3 more
doaj   +1 more source

Synthesis, Characterization and Thermal Analysis of Novel Methylene Bridged Bis-carbazole Based Bisbenzimidazoles

open access: yesHittite Journal of Science and Engineering, 2022
The synthesis of novel bis(3-carbazoly1)methane linked bis-benzimidazoles is described. Construction of symmetrical bis-benzimidazoles on the bis-carbazolylmethane scaffold was succeeded by condensation reaction of benzene-1,2-diamine derivatives with ...
Mehmet Fatih Saglam
doaj   +1 more source

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