Results 21 to 30 of about 19,065 (226)
Synthesis of 4-[10H-Phenothiazin-10-yl(1H-tetrazol-5-yl)-methyl]phenol
Molbank, 2009 This present work aims at synthesizing a novel tetrazole from phenothiazine. Phenothiazine is converted into a nitrile by reacting it with 4-hydroxybenzaldehyde, sodium metabisulphite and sodium cyanide. The nitrile on treatment with NaN3/DMF yielded the
Bathey R. Venkatraman, Helen P. Kavitha
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1-(2,2-Diphenylethyl)-1H-tetrazole
Acta Crystallographica Section E, 2012 The crystal structure of the title compound, C15H14N4, contains chains of coplanar tetrazole rings with the chain direction along b. These are formed through weak hydrogen bonds, donated by the tetrazole H atoms and by one of the H atoms of the methylene
Myrvete Tafili-Kryeziu +3 more
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Direct synthesis of anomeric tetrazolyl iminosugars from sugar-derived lactams
Beilstein Journal of Organic Chemistry, 2021 Herein we present the direct asymmetric synthesis of tetrazole-functionalized 1-deoxynojirimycin derivatives from simple sugars via a Schwartz’s reagent-mediated reductive amide functionalization followed by a variant of the Ugi–azide multicomponent ...
Michał M. Więcław, Bartłomiej Furman
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 A series of 1-aryl-5-(4-arylpiperazine-1-carbonyl)-1H-tetrazols as microtubule destabilizers were designed, synthesised and evaluated for anticancer activity.
Chao Wang +11 more
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Molecules, 2020 A series of novel 7-substituted-5-(1H-indol-3-yl)tetrazolo[1,5-a]pyrimidine-6-carbonitrile was synthesized via a one-pot, three-multicomponent reaction of appropriate aldehydes, 1H-tetrazole-5-amine and 3-cyanoacetyl indole in catalytic triethylamine ...
Mohamed A. A. Radwan +2 more
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Synthesis of tetrazole analogs of amino acids using Fmoc chemistry: isolation of amino free tetrazoles and their incorporation into peptides [PDF]
, 2007 An efficient synthesis of tetrazole analogs of amino acids starting from Nα-Fmoc amino acid (Fmoc = 9-fluorenylmethoxycarbonyl) in a three-step protocol is reported.
Chennakrishnareddy, G. +3 more
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Safe and Efficient Tetrazole Synthesis in a Continuous Flow Microreactor [PDF]
, 2011 Safer flow: The synthesis of 5-substituted tetrazoles in flow (see scheme) is safe, efficient, scalable, requires no metal promoter, and uses a near-equimolar amount of NaN[subscript 3], yet nonetheless displays a broad substrate scope.
Jamison, Timothy F., Palde, Prakash B.
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Synthesis of selected 5-thio-substituted tetrazole derivatives and evaluation of their antibacterial and antifungal activities [PDF]
Journal of the Serbian Chemical Society, 2011 Several 5-thio-substituted tetrazole derivatives were efficiently synthesized by a three-step process. The substituted tetrazol-5-thiol, namely, 1-benzyl-1H-tetrazole-5-thiol (2) was prepared by refluxing commercially available benzyl isothiocyanate (1 ...
NALILU SUCHETHA KUMARI +7 more
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Synthesis, single crystal analysis, biological and docking evaluation of tetrazole derivatives
Heliyon, 2018 Tetrazoles are conjugated nitrogen-rich heterocycles considered as bio-isosteres of carboxylic acids. Tetrazoles owing to their conjugated structures serve as biologically relevant potent scaffolds.
Hamid Aziz +4 more
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Sigmatropic rearrangements in 5-allyloxytetrazoles [PDF]
, 2011 Mechanisms of thermal isomerization of allyl tetrazolyl ethers derived from the carbocyclic allylic alcohols cyclohex-2-enol and 3-methylcyclohex-2-enol and from the natural terpene alcohol nerol were investigated.
Abell +43 more
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