Results 41 to 50 of about 19,065 (226)
Beilstein Journal of Organic Chemistry, 2011 The decomposition of 5-benzhydryl-1H-tetrazole in an N-methyl-2-pyrrolidone/acetic acid/water mixture was investigated under a variety of high-temperature reaction conditions.
Bernhard Gutmann +5 more
doaj +1 more source
Synthesis of 1,5-Disubstituted Tetrazoles in Aqueous Micelles at Room Temperature
Molbank, 2021 The ongoing study is a Ugi-azide four-component reaction for the synthesis of 1,5-disubstituted tetrazole(1,5-DST), which involves an aldehyde, different amines, isocyanides, and as azide’s source the Trimethylsilylazide (TMSN3), in water as solvent ...
Mohammed Abdessalam +3 more
doaj +1 more source
Harnessing Methyltransferase‐Guided Targeting for Sequence‐Specific Proximity Labeling of DNA
Angewandte Chemie, Volume 138, Issue 15, 6 April 2026.A novel methyltransferase‐mediated approach leveraging rationally designed S‐adenosyl‐L‐methionine (SAM) analogues was developed to achieve sequence‐specific DNA labeling but in proximity to the natural transfer site, addressing key limitations of previously established methods, including ligand instability and methylation‐sensitive labeling.
Xiong Chen +8 more
wiley +2 more sources
Noncanonical Amino Acids in the Interrogation of Cellular Protein Synthesis [PDF]
, 2011 Proteins in living cells can be made receptive to bioorthogonal chemistries through metabolic labeling with appropriately designed noncanonical amino acids (ncAAs).
Ngo, John T., Tirrell, David A.
core +2 more sources
Advanced Science, EarlyView.ABSTRACT Inositol pyrophosphates (PP‐InsPs) are central regulators of eukaryotic signaling events. While certain PP‐InsP isomers have been conclusively linked to the regulation of phosphate homeostasis through interaction with SPX domain‐containing proteins in plants, the functions of the recently discovered isomer 4/6‐PP‐InsP5 remain largely unknown ...
Kevin Ritter +10 more
wiley +1 more source
Innovative synthesis of drug-like molecules using tetrazole as core building blocks
Beilstein Journal of Organic ChemistryTetrazole is widely utilized as a bioisostere for carboxylic acid in the field of medicinal chemistry and drug development, enhancing the drug-like characteristics of various molecules.
Jingyao Li +3 more
doaj +1 more source
In silico identification, synthesis and biological evaluation of novel tetrazole inhibitors of MurB [PDF]
, 2018 In the context of antibacterial drug discovery resurgence, novel therapeutic targets and new compounds with alternative mechanisms of action are of paramount importance. We focused on UDP-N- acetylenolpyruvylglucosamine reductase (i.e.
Barreteau, Hélène +7 more
core +3 more sources
Electrostatic Activation of Tetrazoles [PDF]
The Journal of Organic Chemistry, 2020 Photoactivation of tetrazoles to form nitrile imines primed for 1,3-dipolar cycloaddition reactions is of widespread utility in chemistry. In contrast, the corresponding thermal reactions usually possess prohibitively high barriers and have garnered significantly less attention.
Vincent Doan +2 more
openaire +3 more sources
Deciphering Intricacies in Directional CO2 Conversion From Electrolysis to CO2 Batteries
Advanced Energy Materials, EarlyView.This review will delve into the inherent connections and distinctions of CO2‐directed conversion in ECO2RR and CO2 batteries, in terms of product types, catalyst selection, catalytic mechanisms, and electrochemical performances, while proposing a benchmarking framework for the evaluation of CO2 batteries and innovative CO2 battery configurations for ...
Changfan Xu +5 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.We report a modular spin crossover‐photoluminescence (SCO‐PL) system: heteroleptic, mononuclear Fe(II) coordination compounds bearing equatorial BODIPY fluorophores that exhibit synergistic PL response upon spin state switching. Exchanging apical nitrile co‐ligands tunes electronic and structural properties, giving precise control over the SCO and PL ...
Martin Huber +4 more
wiley +1 more source