Results 61 to 70 of about 12,506 (227)

Synthesis of tetrazole derivatives as potential antituberculotics [PDF]

, 2011
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Inorganic and Organic Chemistry Candidate: Jan Němeček Supervisor: PharmDr. Jaroslav Roh, PhD.
Němeček, Jan
core   +1 more source

Photoinduced Tetrazole-Based Functionalization of Off-Stoichiometric Clickable Microparticles

, 2017
We report the preparation of tetrazole-containing step-growth microparticles and the subsequent use of photoinduced nitrile imine-mediated tetrazole-ene cycloaddition (NITEC) reactions on the particles with spatiotemporal control.
Christopher Barner‐Kowollik, Schenzel, Alexander, Willenbacher, Johannes, Zieger, Markus M., Johannes Willenbacher, Markus M. Zieger, Chen Wang, Alexander Schenzel, Bowman, Christopher N., Christopher N. Bowman, Wegener, Martin, Wang, Chen, Barner-Kowollik, Christopher, Martin Wegener   +13 more
core   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

Mild C─F Activation of Azido(per)Fluoroalkanes

Chemistry – A European Journal, EarlyView.
Mild and selective activation of C(sp3)–F bonds in azido(per)fluoroalkanes using thiolates was developed, leading to novel functionalized azides. The reaction is initiated by nucleophilic attack of the sulfur atom to the terminal nitrogen of the azido group, followed by fluoride ion elimination.
Olena Shaitanova, María Martínez Mallo, Sergii Suikov, Blanka Klepetářová, Josef Filgas, Petr Slavíček, Lucie Bednárová, Petr Beier   +7 more
wiley   +1 more source

Understanding reactivity patterns in light-induced nitrile imine mediated tetrazole-ene cycloadditions

, 2017
A rationale for predicting photochemical tetrazole activation in the popular nitrile imine mediated tetrazole–ene cycloaddition (NITEC) reaction, based on a combined theoretical and experimental study, is reported.
Lederhose, Paul, Blasco, Eva, James P. Blinco, Yuuki Sugawara, Christopher Barner‐Kowollik, Eva Blasco, Kelterer, Anne-Marie, Blinco, James P., Barner-Kowollik, Christopher, Sugawara, Yuuki, Paul Lederhose, Anne‐Marie Kelterer   +11 more
core   +1 more source

Cyclopropylamine‐Derived Distonic Iminium Radicals: Photoinduced Strategies in Chemo‐ and Stereo‐Selective Synthesis

Chemistry – A European Journal, EarlyView.
Cyclopropylamines have emerged as powerful photocatalytic building blocks. Upon light‐induced single‐electron oxidation, they undergo strain‐release ring opening to generate distonic iminium radicals that enable diverse transformations, including ring‐opening functionalization, formal [3 + 2] cycloadditions, radical cascades, and asymmetric bond ...
Maria Chiara Cabua, Alberto Luridiana, Francesco Secci, Emanuele Cocco   +3 more
wiley   +1 more source

Rapidly Diversifying Hydrogen‐Bonded Organic Frameworks With Permanent Porosity

Angewandte Chemie, Volume 138, Issue 36, 1 September 2026.
This article reviews diversifying hydrogen‐bonded organic frameworks (HOFs) with permanent porosity reported over the past 15 years, based on the molecular structures of their constituent tectons. Furthermore, several distinctive aspects and concepts are described, such as permanent porosity, isostructural (isoreticular) HOFs, and multicomponent mixed ...
Taito Hashimoto, Ichiro Hisaki
wiley   +2 more sources

Phosphonomethyl (Thio)Phosphonamidite Reagents for the Construction of Phosphonylmethyl Phosphono(Di)Thioate Mono‐ and Diesters

Chemistry – A European Journal, EarlyView.
A set of new phosphonomethyl (thio)phosphonamidite reagents is introduced to generate unprecedented pyrophosphate mimetics. The versatile P(III)‐P(V) reagents allow for the construction of various pyrophosphate isosteres, and the applicability of the chemistry is illustrated in the assembly of a diverse set of stabilized CDP‐glycerol and CDP‐ribitol ...
Pascal Balić, Roy Steneker, Gijsbert A. van der Marel, Jeroen D. C. Codée, Dmitri V. Filippov   +4 more
wiley   +1 more source

Chelation‐Assisted Metal‐Catalyzed Ligation and Cleavage Reactions for Chemical Biology

European Journal of Organic Chemistry, EarlyView.
Chelation‐assisted transition metal catalysis has emerged as a promising complement to bioorthogonal click chemistry for studying biological processes. By pre‐organizing catalytic metal centers, designed coordinating substrates enhance reactivity and biocompatibility, enabling site‐selective ligation and decaging reactions in complex biological media ...
Emilie Plantiveau, Maxime Riberaud, Frédéric Taran, Antoine Sallustrau   +3 more
wiley   +1 more source

Chelating ability of proctolin tetrazole analogue [PDF]

, 2006
The aim of the investigation was to establish the chelating ability of a new proctolin analogue of the sequence Arg-Tyr-LeuΨ[CN4]Ala-Thr towards copper(II) ions. The insertion of the tetrazole moiety into the peptide sequence has considerably changed the
Nachman, Ronald, Zabrocki, Janusz, Łodyga-Chruścińska, Elżbieta, Olejnik, Jadwiga, Chruściński, Longin, Sanna, Daniele, Micera, Giovanni   +6 more
core   +2 more sources