Results 11 to 20 of about 7,641 (139)
1-(2,2-Diphenylethyl)-1H-tetrazole
Acta Crystallographica Section E, 2012 The crystal structure of the title compound, C15H14N4, contains chains of coplanar tetrazole rings with the chain direction along b. These are formed through weak hydrogen bonds, donated by the tetrazole H atoms and by one of the H atoms of the methylene
Myrvete Tafili-Kryeziu +3 more
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Direct synthesis of anomeric tetrazolyl iminosugars from sugar-derived lactams
Beilstein Journal of Organic Chemistry, 2021 Herein we present the direct asymmetric synthesis of tetrazole-functionalized 1-deoxynojirimycin derivatives from simple sugars via a Schwartz’s reagent-mediated reductive amide functionalization followed by a variant of the Ugi–azide multicomponent ...
Michał M. Więcław, Bartłomiej Furman
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 A series of 1-aryl-5-(4-arylpiperazine-1-carbonyl)-1H-tetrazols as microtubule destabilizers were designed, synthesised and evaluated for anticancer activity.
Chao Wang +11 more
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Angewandte Chemie, EarlyView.This work develops a spray‐assisted in situ assembly technique to construct AHF materials with nitrogen/oxygen‐regulated one‐dimensional channels on glass fiber, providing abundant active sites and enabling rapid transport for lithium ions. Subsequently, phosphate flame retardants are encapsulated via in situ polymerization, resulting in a thermally ...
Shun Wang +9 more
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Molecules, 2020 A series of novel 7-substituted-5-(1H-indol-3-yl)tetrazolo[1,5-a]pyrimidine-6-carbonitrile was synthesized via a one-pot, three-multicomponent reaction of appropriate aldehydes, 1H-tetrazole-5-amine and 3-cyanoacetyl indole in catalytic triethylamine ...
Mohamed A. A. Radwan +2 more
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Synthesis, single crystal analysis, biological and docking evaluation of tetrazole derivatives
Heliyon, 2018 Tetrazoles are conjugated nitrogen-rich heterocycles considered as bio-isosteres of carboxylic acids. Tetrazoles owing to their conjugated structures serve as biologically relevant potent scaffolds.
Hamid Aziz +4 more
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Angewandte Chemie, EarlyView.Azidoborylene photolysis results in the isolation of a reactive C═B═N═C heterocumulene bearing an ambiphilic boron centre. Addition of 3O2 to this species results in the clean conversion to a unique example of a dioxaborirane. ABSTRACT Oxidation of the formal boron(0) complex MeCAAC2B in the presence of tetrabutylammonium azide leads to the formation ...
Hayley King +4 more
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Synthesis of selected 5-thio-substituted tetrazole derivatives and evaluation of their antibacterial and antifungal activities [PDF]
Journal of the Serbian Chemical Society, 2011 Several 5-thio-substituted tetrazole derivatives were efficiently synthesized by a three-step process. The substituted tetrazol-5-thiol, namely, 1-benzyl-1H-tetrazole-5-thiol (2) was prepared by refluxing commercially available benzyl isothiocyanate (1 ...
NALILU SUCHETHA KUMARI +7 more
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Activation of TREK-1 and TREK-2 Two-Pore Domain Potassium Channels by the K<sub>v</sub>4 Channel Modulator, NS5806. [PDF]
Pharmacol Res PerspectABSTRACT NS5806 is a diaryl‐urea small molecule developed for the treatment of pain and neurological disorders. A potent activator of Kv4.3 potassium channels, it is widely used to study Kv4 channel physiology in excitable cells, including trigeminal neurons.
Veale EL +4 more
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International Journal of Electrochemical Science, 2019 In this theoretical study, calculations for the three types of the tetrazole which are 2-(1H-Tetrazole-5-yl)-3-phenylacrylonitrile, 2-(1H-Tetrazole-5-yl)-3-(4-nitrophenylacrylonitrile), and 2-(1H-Tetrazole-5-yl)-3-(4- hydroxyphenyl acrylonitrile) showing
Mahmud Ibrahim Elusta +2 more
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