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Bu4NI Catalyzed Radical Induced Regioselective N-Alkylations and Arylations of Tetrazoles Using Organic Peroxides/Peresters.

Journal of Organic Chemistry, 2020
A Bu4NI-catalyzed regioselective N2-methylation, N2-alkylation and N2-arylation of tetrazoles have been achieved using tert-butyl hydroperoxide (TBHP) as the methyl, alkyl diacyl peroxides as the primary alkyl, alkyl peresters as the secondary and ...
Suresh Rajamanickam   +7 more
semanticscholar   +1 more source

An Expeditious Approach to Tetrazoles from Amides Utilizing Phosphorazidates.

Organic Letters, 2020
A novel method was developed for the synthesis of tetrazoles from amides utilizing diphenyl phosphorazidate or bis(p-nitrophenyl) phosphorazidate as both the activator of amide-oxygen for elimination and azide source.
Kotaro Ishihara, T. Shioiri*, M. Matsugi
semanticscholar   +1 more source

Tetrazoles: XLV. Amidoalkylation of 5-Substituted Tetrazoles

Russian Journal of Organic Chemistry, 2003
Amidoalkylation of 5-aryl(hetaryl)tetrazoles with N-hydroxymethylamides of aliphatic and aromatic carboxylic acids occurs regioselectively and yields mainly 5-aryl(hetaryl)-2-acylaminomethyltetrazoles. These compounds arefairly stable in neutral media but are smoothly deprotected by the action of aqueous sodium hydroxide or hydrochloric acid.
L. V. Myznikov   +3 more
openaire   +1 more source

Tetrazoles

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

Magnetic nanomaterials catalyzed synthesis of tetrazoles

, 2020
Tetrazoles are valuable molecules in pharmaceutical and agriculture chemistry, because they are excited in many drugs, natural products and biologically active molecules.
Muhammad Aqeel Ashraf   +4 more
semanticscholar   +1 more source

Tetrazoles for biomedicine

Russian Chemical Reviews, 2019
The tetrazole ring is an important pharmacophore. It is a structural component in many drugs, drug candidates (or lead compounds) and various biochemical reagents.
E. A. Popova, R. Trifonov, V. Ostrovskii
semanticscholar   +1 more source

A practical multigram-scale method for the green synthesis of 5-substituted-1H-tetrazoles in deep eutectic solvent

Tetrahedron Letters, 2019
A series of 5-substituted-1 H -tetrazoles have been efficiently synthesized in moderate to excellent yields (68–90%) under mild reaction conditions by combining aryl aldehydes, hydroxylamine hydrochloride with sodium azide in the presence of catalytic ...
Xingquan Xiong   +3 more
semanticscholar   +1 more source

Ir-Catalyzed Intramolecular Transannulation/C(sp2)-H Amination of 1,2,3,4-Tetrazoles by Electrocyclization.

Journal of the American Chemical Society, 2018
An efficient strategy for the intramolecular denitrogenative transannulation/C(sp2)-H amination of 1,2,3,4-tetrazoles bearing C8-substituted arenes, heteroarenes, and alkenes is described.
Sandip Das   +3 more
semanticscholar   +1 more source

Synthesis and characterization of MCM-41@AMPD@Zn as a novel and recoverable mesostructured catalyst for oxidation of sulfur containing compounds and synthesis of 5-substituted tetrazoles

Microporous and Mesoporous Materials, 2018
In this paper we report synthesis of a heterogeneous catalyst for the first time, by anchoring a zinc complex to mesoporous silica MCM-41. The structure of functionalized MCM-41 was characterized by FT-IR, XRD, SEM, TEM, TGA, ICP, EDA and BET techniques.
S. Molaei   +3 more
semanticscholar   +1 more source

Synthesis, molecular docking and xanthine oxidase inhibitory activity of 5-aryl-1H-tetrazoles.

Bioorganic chemistry (Print), 2018
5-Aryl-1H-tetrazoles (1-24) were synthesized and screened for their xanthine oxidase (XO) inhibitory activity using allopurinol as standard inhibitor (IC50 = 2.0 ± 0.01 µM).
Itrat Fatima   +6 more
semanticscholar   +1 more source

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