Results 21 to 30 of about 1,810 (150)

TESTE DE TETRAZÓLIO EM SEMENTES DE ESPÉCIES DO DOMÍNIO FITOGEOGRÁFICO AMAZÔNICO

Agrotrópica (Itabuna), 2021
O objetivo deste trabalho foi o levantamento de dados através de pesquisas por metodologias adequadas para a aplicação do teste de tetrazólio em sementes nativas do domínio fitogeográfico amazônico.
Pamela Porfirio Gonçalves, J. Garlet
semanticscholar   +1 more source

How Single Site Mutations Can Help Understanding Structure Formation of Amyloid β1−40

Macromolecular Bioscience, Volume 23, Issue 5, May 2023., 2023
The contact between phenylalanine 19 and leucine 34 in Aβ molecules is highly conserved suggesting a particular significance for Aβ misfolding and, in turn, for its neurotoxicity. Point mutations in Aβ peptides at the contact F19−L34 help understanding this importance.
Benedikt Schwarze, Daniel Huster
wiley   +1 more source

METODOLOGIAS PARA DETERMINAR QUALIDADE FISIOLÓGICA EM SEMENTES DE FEIJÃO ENFATIZANDO O TESTE DE TETRAZÓLIO

, 2021
A cultura do feijao ( Phaseolus vulgaris L.) tem destaca no setor do agronegocio nacional por se tratar de uma especie amplamente cultivada em todo o pais.
Débora Perdigão Tejo, C. Fernandes, M. R. Ávila   +2 more
semanticscholar   +1 more source

Aplicação mobile para coleta de dados de análise do teste de tetrazólio

Anais do XVIII Congresso Latino-Americano de Software Livre e Tecnologias Abertas (Latinoware 2021), 2021
Este artigo apresenta o desenvolvimento de um software mobile OpenSource para coleta de dados durante a realização do teste de tetrazólio em laboratórios de sementes.
Luís Henrique Manosso Von Mecheln, Paulo Lopes de Menezes, P. L. D. Paula Filho   +2 more
semanticscholar   +1 more source

Graphene‐Based Materials in Dental Applications: Antibacterial, Biocompatible, and Bone Regenerative Properties

International Journal of Biomaterials, Volume 2023, Issue 1, 2023., 2023
Graphene‐based materials have been shown to have advantageous properties in biomedical and dental applications due to their high mechanical, physiochemical, antibacterial, and stem cell differentiating properties. Although graphene‐based materials have displayed appropriate biocompatible properties when used in implant materials for orthopedic ...
A. G. Williams, E. Moore, A. Thomas, J. A. Johnson, Alexander Seifalian   +4 more
wiley   +1 more source

Endoplasmic reticulum oxidoreductin 1‐alpha deficiency and activation of protein translation synergistically impair breast tumour resilience

British Journal of Pharmacology, Volume 179, Issue 23, Page 5180-5195, December 2022., 2022
Background and Purpose Endoplasmic reticulum (ER) stress triggers an adaptive response in tumours which fosters cell survival and resilience to stress. Activation of the ER stress response, through its PERK branch, promotes phosphorylation of the α‐subunit of the translation initiation factor eIF2, thereby repressing general protein translation and ...
Ersilia Varone, Alessandra Decio, Maria Chiara Barbera, Marco Bolis, Laura Di Rito, Federica Pisati, Raffaella Giavazzi, Ester Zito   +7 more
wiley   +1 more source

Viabilidade de sementes armazenadas de Himatanthus sucuuba Wood pelo teste de tetrazólio

, 2021
Himatanthus sucuuba is an Amazonian tree species of importance in traditional medicine because of its therapeutic properties. Estimates of seed viability are still scarce, so it is necessary to develop rapid tests to evaluate seed quality. The objectives
L. H. Sáenz-Ramírez, Angela Maria da Silva Mendes, Angela Maria Imakawa, P. D. T. B. Sampaio, Maria da Glória Gonçalves de Melo   +4 more
semanticscholar   +1 more source

FOXM1 Inhibition Enhances the Therapeutic Outcome of Lung Cancer Immunotherapy by Modulating PD‐L1 Expression and Cell Proliferation

Advanced Science, Volume 9, Issue 29, October 14, 2022., 2022
In this study, the authors show that FOXM1 selectively regulates PD‐L1 expression by binding directly to the PD‐L1 promoter. The FOXM1 inhibitor significantly lowers PD‐L1 levels and tumor growth in vitro and in vivo without any side effects on vital normal tissues.
Hamadi Madhi, Jeon‐Soo Lee, Young Eun Choi, Yan Li, Myoung Hee Kim, Yongdoo Choi, Sung‐Ho Goh   +6 more
wiley   +1 more source

Development of a potent small‐molecule degrader against oncogenic BRAFV600E protein that evades paradoxical MAPK activation

Cancer Science, Volume 113, Issue 8, Page 2828-2838, August 2022., 2022
In this study, we developed chimeric compounds, proteolysis targeting chimeras (PROTACs), that target BRAF V600E protein for degradation. CRBN(BRAF)‐24, the most effective chimera, selectively degraded BRAF V600E in a ubiquitin‐proteasome system (UPS)‐dependent manner and inhibited the proliferation of BRAF V600E‐driven cancer cells.
Nobumichi Ohoka, Masanori Suzuki, Takuya Uchida, Yoshinori Tsukumo, Masayuki Yoshida, Takao Inoue, Hitoshi Ohki, Mikihiko Naito   +7 more
wiley   +1 more source

Baseline and time‐updated factors in preclinical development of anionic dendrimers as successful anti‐HIV‐1 vaginal microbicides

WIREs Nanomedicine and Nanobiotechnology, Volume 14, Issue 3, May/June 2022., 2022
Key preclinical steps in the development of a vaginal microbicide against HIV‐1 infection to lead to clinical trials. Abstract Although a wide variety of topical microbicides provide promising in vitro and in vivo efficacy, most of them failed to prevent sexual transmission of human immunodeficiency virus type 1 (HIV‐1) in human clinical trials.
Ignacio Rodríguez‐Izquierdo, Daniel Sepúlveda‐Crespo, Jose María Lasso, Salvador Resino, Ma Ángeles Muñoz‐Fernández   +4 more
wiley   +1 more source