Results 121 to 130 of about 675,988 (246)
ABSTRACT The roots of the climbing shrub Cryptolepis sanguinolenta are traditionally used in West Africa for the treatment of malaria. The principal constituent, cryptolepine (1), has been shown to have antimalarial activity but there are concerns regarding its toxicity on account of its DNA‐intercalating property.
Elodie Chenu +7 more
wiley +1 more source
PDMS samples were covalently coated with mucin glycoproteins and then treated with either plasma activated water (PAW) or saline (PAS) as a means of disinfection. The samples could be successfully sterilized without compromising the structural integrity or functionality of those coatings.
Bernardo Miller Naranjo +4 more
wiley +1 more source
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy +4 more
wiley +1 more source
ABSTRACT Hymenocardia acida Tul. is a medicinal plant used in Angola to treat microbial diseases. It is a well‐known plant among local populations; however, few studies have focused on the assessment of phytochemicals associated with their biological activities.
Ntsoaki Joyce Malebo +4 more
wiley +1 more source
Abstract BACKGROUND Valorizing sugar‐rich food waste in biorefineries offers a sustainable route to bio‐based products. Grapefruit peel (GP), representing about 50% of the fruit's weight, is rich in sugars (soluble and insoluble) and polyphenols such as flavonoids.
María del Prado García‐Aparicio +2 more
wiley +1 more source
Human mesenchymal stromal cells (MSCs) were engineered to secrete an isoleucine‐zippered soluble trimeric TRAIL (SCZT) and evaluated with trichostatin A (TSA) to overcome TRAIL resistance. TSA upregulated DR5 and amplified caspase‐8–dependent apoptosis in vitro; in vivo, tumor‐homing MSCs combined with TSA suppressed the growth of both TRAIL‐sensitive ...
Ryosuke Uchibori +2 more
wiley +1 more source
Cytotoxicity of ammonia‐ and water‐based silver fluoride treatments
Abstract This study aims to investigate the trans‐dentinal and direct cell viability of ammonia‐ and water‐based silver fluoride treatments. Deep dentin discs were prepared, balanced for permeability and autoclaved. Three‐dimensional cultures of odontoblast‐like cells were transferred to the pulpal aspect of the dentin slices inside perfusion split ...
Merve Uctasli +3 more
wiley +1 more source
Schematic diagram of the triggering mechanism of necroptosis after cerebral ischemia. First, CCL11 targetedly binds to CCR3 on the surface of astrocytes and upregulates the expression of CCR3. After CCR3 activation, it triggers the transcriptional activation of necroptosis.
Han Yin +10 more
wiley +1 more source

