Results 31 to 40 of about 750,402 (305)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
AIMS Public HealthBackgroundType 2 diabetes mellitus (T2DM) is a prevalent chronic disease in the United States and healthcare resources used to manage the disease are disproportionately consumed by a small subset of users. Consequently, there is a potential to reduce the
Lixian Zhong +9 more
doaj +1 more source
Education Policy Analysis Archives, 2019 In Texas, local taxpayers fund the majority of educational facilities construction and maintenance costs, with local wealth influencing facilities outcomes.
Marialena D. Rivera, Sonia Rey Lopez
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Differences by Economic Status in Grade 3 Reading Performance: A Texas Multiyear Study [PDF]
Athens Journal of Education, 2019 In this investigation, differences in the reading performance as a function of degree of economic disadvantage for Texas Grade 3 students were examined.
Jenny A. M. McGown, John R. Slate
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Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Гуманитарные и юридические исследования, 2021 The paper features the history of shaping the state border between the USA and Mexico in the XIX century in the context of the US foreign policy as well as the history of colonization of the territories which now make up the borderland region of present ...
Tat’yana Pantyukhina
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The emergence of a texas collaboration to improve well-being in learning health systems
Medical Education Online, 2021 Prior models of well-being have focused on resolving issues at different levels within a single institution. Changes over time in medicine have resulted in massive turnover and reduced clinical hours that portray a deficit-oriented system.
Toi B. Harris +4 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
The Texas Two-Step, Hmong Style: A Delicate Dance Between Culture and Ethnicity [PDF]
Hmong Studies Journal, 2006 Over the last thirty years since relocation, individual Hmong refugee communities in America have evolved with varying needs and outcomes adding to their complexity and diversity in the United States. There is a noted lack of research that examines these
Faith Nibbs
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