Results 91 to 100 of about 811,653 (307)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Detect Language of Transliterated Texts

CoRR, 2020
10 pages, 8 figures, 3 ...
openaire   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Relay Protection Setting Sheet Detection and Recognition Approach Based on YOLOv8-CRNN-CTC

IEEE Access
To address the challenging recognition of relay protection setting characters in industrial scenarios due to their small size, dense arrangement, complex backgrounds, and susceptibility to lighting effects, a two-stage automatic recognition method ...
Xiaohao Lv, Shitao Gao, Guoli Miao, Zonglei Chen   +3 more
doaj   +1 more source

MPOE Based Adaptive Multiuser Detection [PDF]

, 2008
Introduction . Continuous Time Discrete Time . MPOE Based Methods: Introduction . Probability of Error Expressions Probability Distribution of the Decision Statistics Joint Probability Conditional Probability .
Multiuser Detection Brief
core  

OSCAR4: a flexible architecture for chemical text-mining. [PDF]

, 2011
The Open-Source Chemistry Analysis Routines (OSCAR) software, a toolkit for the recognition of named entities and data in chemistry publications, has been developed since 2002.
David M Jessop, Peter Murray-Rust, Lezan Hawizy, Sam E Adams, Murray-rust, Peter, Egon L Willighagen, Adams, Sam E, Jessop, David M, Willighagen, Egon L, Hawizy, Lezan   +9 more
core   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

KACST Arabic Text Classification Project: Overview and Preliminary Results [PDF]

, 2008
Electronically formatted Arabic free-texts can be found in abundance these days on the World Wide Web, often linked to commercial enterprises and/or government organizations. Vast tracts of knowledge and relations lie hidden within these texts, knowledge
Al-Rajeh, A., Althubaity, A., Almuhareb, A., Khorsheed, M., Alharbi, S.   +4 more
core  

Text Detection Forgot About Document OCR [PDF]

, 2023
Detection and recognition of text from scans and other images, commonly denoted as Optical Character Recognition (OCR), is a widely used form of automated document processing with a number of methods available.
Olejniczak, Krzysztof, Šulc, Milan
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source