Results 51 to 60 of about 40,470,474 (303)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Literal Encoding: Text is a first-class data encoding
CoRR, 2020 6 pages, 14 ...
openaire +2 more sources
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Encoding Disappearing Characters: The Case of Twentieth-Century Japanese-Canadian Names
Journal of the Text Encoding Initiative, 2019 The Landscapes of Injustice project seeks to encode mid-twentieth-century documents by and about the Japanese-Canadian community so they are accessible to modern audiences.
Stewart Arneil
doaj +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Journal of the Text Encoding Initiative, 2019 In the digital age, the legal situation of the data produced in research projects that are relevant to an international research community such as the TEI is becoming more and more important.
Vanessa Hannesschläger
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Encoding for Endangered Tibetan Texts
Digital Humanities Quarterly, 2007 For over a thousand years, Tibet has preserved and translated ancient Buddhist Sutras from India, keeping the tradition of Buddhist philosophy and meditation alive long after it died out in India by the 12th Century. Recent efforts to digitize materials from this textual tradition offer opportunities to broaden the circulation of rare materials to the ...
openaire +2 more sources
The TUSNELDA annotation standard : an XML encoding standard for multilingual corpora supporting various aspects of linguistic research [PDF]
, 2000 This paper proposes a corpus encoding standard that meets the needs of linguistic research using a variety of linguistic data structures. The standard was developed in SFB 441, a research project at the University of Tuebingen.
Wagner, Andreas, Kallmeyer, Laura
core
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source