Results 31 to 40 of about 182,446 (269)

Encoding Crime and Punishment in TEI: The Digital Processing of Early Modern Broadsheets from Vienna

open access: yesJournal of the Text Encoding Initiative, 2019
In this project note, we introduce a set of printed single broadsheets in German, recently discovered in two of Vienna’s libraries, which, thanks to their digitization, annotation, and online publication by the Austrian Centre for Digital Humanities ...
Claudia Resch   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The CLiGS Textbox: Building and Using Collections of Literary Texts in Romance Languages Encoded in TEI XML

open access: yesJournal of the Text Encoding Initiative, 2019
The CLiGS textbox is published by the Computational Literary Genre Stylistics (CLiGS) group. The textbox is the group’s publication channel for several collections of literary texts.
Christof Schöch   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A TEI Customization for Writing TEI Customizations

open access: yesJournal of the Text Encoding Initiative, 2019
A schema, in general, is intended to be used to check a document for errors before those errors cause problems in processing. However, schemas can also help us write our documents.
Syd Bauman
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Encoding Disappearing Characters: The Case of Twentieth-Century Japanese-Canadian Names

open access: yesJournal of the Text Encoding Initiative, 2019
The Landscapes of Injustice project seeks to encode mid-twentieth-century documents by and about the Japanese-Canadian community so they are accessible to modern audiences.
Stewart Arneil
doaj   +1 more source

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