Results 91 to 100 of about 488,004 (308)

Text line segmentation of ancient Thai manuscripts on palm leaves [PDF]

, 2012
Segmentation of handwritten scripts with overlapping text is one of the challenging tasks in the pre-processing for document recognition and optical character recognition (OCR) systems.
Fung, C.C., Chamchong, R.
core   +1 more source

ABCNet: Real-time scene text spotting with adaptive Bezier-curve network [PDF]

, 2020
Scene text detection and recognition has received increasing research attention. Existing methods can be roughly categorized into two groups: character-based and segmentation-based.
Shen, C., Jin, L., Liu, Y., Chen, H., He, T., Wang, L.   +5 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Intelligent Logistics Sorting Technology Based on PaddleOCR and SMITE Parameter Tuning

Applied Sciences
To address the current reliance on manual labor in traditional logistics sorting operations, which leads to low sorting efficiency and high operational costs, this study presents the design of an unmanned logistics vehicle based on the Robot Operating ...
Zhaokun Yang, Yue Li, Lizhi Sun, Yufeng Qiu, Licun Fang, Zibin Hu, Shouna Guo   +6 more
doaj   +1 more source

Performance of hidden Markov model and dynamic Bayesian network classifiers on handwritten Arabic word recognition [PDF]

, 2011
This paper presents a comparative study of two machine learning techniques for recognizing handwritten Arabic words, where hidden Markov models (HMMs) and dynamic Bayesian networks (DBNs) were evaluated.
Jinchang Ren, Alkhateeb, Jawad H., Jiang, J, Ren, J, Pauplin, Olivier, Alkhateeb, JH, Ren, Jinchang, Jawad H. AlKhateeb, Olivier Pauplin, Pauplin, O, Jiang, Jianmin, Jianmin Jiang   +11 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Localization and recognition of the scoreboard in sports video based on SIFT point matching [PDF]

, 2011
In broadcast sports video, the scoreboard is attached at a fixed location in the video and generally the scoreboard always exists in all video frames in order to help viewers to understand the match’s progression quickly.
Guo, Jinlin, Gurrin, Cathal, Smeaton, Alan F., Foley, Colum, Lao, Songyang   +4 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source