Results 41 to 50 of about 232,431 (349)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Die tekskritiek van die Nuwe Testament (1): Die huidige metodologiese situasie

open access: yesVerbum et Ecclesia, 1991
The textual criticism of the New Testament (1): The current methodological Situation This first article in a two-part series on the textual criticism of the New Testament focuses on the current state of affairs regarding textcritical methodology ...
L. D. Jacobs
doaj   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

'Verba Chrysidis morientis'. Note filologiche ed esegetiche a Eugraph. ad Ter. Andr. 282-298

open access: yesGriseldaonline, 2023
Il contributo propone un’analisi filologica del commento di Eugrafio ad Andr. 281-298 (27,3-29,15 W.): vengono discussi ed interpretati i passaggi che sembrano maggiormente problematici e, dove necessario, sono suggerite delle proposte di emendazione al ...
Luigi Pirovano
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Discourse considerations in Genesis 1:1-2:4a

open access: yesKansas Working Papers in Linguistics, 1981
Traditional, word-for-word translations of the Priestly Source's creation hymn have led to misrepresentations of the primary emphases of the text. An analysis of the event line as determined by the use of the waw conversive construction clears up the ...
McLaughlin, John E.
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Re-examining New Testament Textual-Critical Principles and Practices Used to Negate Inerrancy [PDF]

open access: yes, 1982
A consistent application of the most widely accepted principles and practices of New Testament textual criticism has resulted in stark declarations that the original autographs contained factual errors.
Borland, James A.
core  

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