Results 41 to 50 of about 4,111 (252)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Die tekskritiek van die Nuwe Testament (2): �n Oefening in teorie en praktyk

open access: yesVerbum et Ecclesia, 1992
The textual criticism of the New Testament (2): An exercise in theory and practice This concluding article on New Testament textual criticism focuses on the practical application of a workable method for the evaluation of textual variants in the ...
L. D. Jacobs
doaj   +1 more source

Collocation as a method in textual criticism of Hadith [PDF]

open access: yesتحقیقات علوم قرآن و حدیث, 2013
Hadith in the process of transmission to the next generations exposed to some damagesincluding,distortion and displacement. This phenomenon necessitate to provide methods in examination and emendation of hadith.
Seyed Kazem Tabatabaeipour   +1 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

“The Romantic of Textual Criticism” Konstantin Ivanovich Khalabayev [PDF]

open access: yesЛитературный факт
The article is devoted to the reconstruction of the biography of Konstantin Ivanovich Khalabaev (1885–1941), the founder of Soviet textology as an academic science. The scholar did not leave a single scientific article or monograph, there is not a single
Petr A. Druzhinin
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Notas sobre el texto de El Criticón, de Gracián

open access: yesCriticón, 2015
El Criticón, by Gracián, was first printed in 1651 (first part), 1653 (second part) and 1657 (third part). The first attempt at a critical edition was made by Miguel Romera-Navarro in 1938-1940.
José Javier Rodríguez Rodríguez
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Discourse considerations in Genesis 1:1-2:4a

open access: yesKansas Working Papers in Linguistics, 1981
Traditional, word-for-word translations of the Priestly Source's creation hymn have led to misrepresentations of the primary emphases of the text. An analysis of the event line as determined by the use of the waw conversive construction clears up the ...
McLaughlin, John E.
doaj   +1 more source

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