Results 41 to 50 of about 2,407 (209)
Acoustically Activatable Drug‐Loaded Nanodroplets for Mechanochemical Therapy in Solid Tumors
Advanced Science, EarlyView.Microfluidically fabricated drug‐loaded nanodroplets are sequentially activated by dual‐frequency ultrasound through acoustic droplet vaporization followed by bubble collapse, enabling spatially controlled drug release and mechanical tumor fractionation, resulting in synergistic mechanochemotherapy and prolonged survival.
Tiran Bercovici +4 more
wiley +1 more source
Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice
Advanced Science, EarlyView.CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu +8 more
wiley +1 more source
Leveraging TFR-BERT for ICD Diagnoses Ranking
, 2023 This work describes applying a transformer-based ranking solution to the specific problem of ordering ICD diagnoses codes. Taking advantage of the TFR-BERT framework and adapting it to the biomedical context using pre-trained and publicly available language representation models, namely BioBERT, BlueBERT and ClinicalBERT (Bio + Discharge Summary BERT ...
Ana Silva 0002 +5 more
openaire +3 more sources
Advanced Science, EarlyView.(A) Establishment and characterization of the osteosarcoma‐targeted dual‐delivery nanoplatform mBAP1/siENO1@LNP‐OTP for simultaneous regulation of BAP1 and ENO1 in tumor cells. (B) After intravenous administration, mBAP1/siENO1@LNP‐OTP preferentially accumulates at tumor sites through OTP‐mediated targeting.
Yechao Shen +13 more
wiley +1 more source
Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis
Animal Research and One Health, EarlyView.Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang +11 more
wiley +1 more source
The Ubiquity of Twisted Flux Ropes in the Quiet Sun
The Astrophysical Journal LettersModels and observations have demonstrated that twisted flux ropes (TFRs) play a significant role in the structure and eruptive dynamics of active regions.
Tahar Amari +8 more
doaj +1 more source
Canine parvovirus-like particles, a novel nanomaterial for tumor targeting
Journal of Nanobiotechnology, 2006 Specific targeting of tumor cells is an important goal for the design of nanotherapeutics for the treatment of cancer. Recently, viruses have been explored as nano-containers for specific targeting applications, however these systems typically require ...
Destito Giuseppe +3 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective Regeneration and expansion of Treg by low‐dose interleukin‐2 (IL‐2) therapy is considered a potential treatment strategy for a wide range of autoimmune diseases. To provide a pathophysiologically‐based rationale for low‐dose IL‐2 therapy, we investigated whether reversible defects in the Treg–IL‐2 axis emerge in inflammatory myopathies ...
Justus Ohmes +10 more
wiley +1 more source
Cumhuriyet Üniversitesi İktisadi ve İdari Bilimler Dergisi, 2015 Yeni Türk Ticaret Kanunu ile muhasebe kayıtlarının tutulması ve finansal tabloların düzenlenmesi, Uluslararası Muhasebe Standartları (UMS=IAS=International Accounting Standards) ve Uluslararası Finansal Raporlama Standartları (UFRS=IFRS=International ...
Şakir Dızman
doaj
Sosyal Ekonomik Araştırmalar Dergisi, 2014 Muhasebe uygulamalarına yön veren kurallar bütünü olarak adlandırılan standartların temeli muhasebe ilkelerine, muhasebe ilkelerinin temeli ise muhasebenin temel kavramlarına dayanmaktadır.
Yunus Ceran, Merve Öz
doaj +1 more source