Results 51 to 60 of about 3,584 (234)
Advanced Science, EarlyView.We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen +5 more
wiley +1 more source
ACCOUNTING OF SALE AND LEASEBACK TRANSACTIONS ACCORDING TO TFRS 16 AND TAS 17 STANDARDS
, 2020 İşletmelerin finansal kiralama şirketine satmış olduğu varlığı daha sonra finansal kiralama şirketinden kiralaması anlamına gelensat-geri kirala yöntemi, Türkiye’de 6361 sayılı finansal kiralama, faktoring ve finansman şirketleri kanununun ...
Tulum, Saadet
core +1 more source
Yüzüncü Yıl Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2018 TMS/TFRS, Türkiye’de Türkçeye çevrilerek aynen uygulanmaktadır. Bu standartlar, 09.07.2009 ve 16.05.2005 tarihlerinde yayımlanmıştır. 14.02.2011 tarih ve 27846 Sayılı Resmi Gazete’de 6102 Sayılı TTK’nın 88.
Murat Kara
doaj
Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis
Advanced NanoBiomed Research, EarlyView.Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia +10 more
wiley +1 more source
Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis
Animal Research and One Health, EarlyView.Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang +11 more
wiley +1 more source
Nine TFRs of interest and their divergent neighbors.
, 2012 Nine TFRs of interest and their divergent neighbors.
Leslie Cuthbertson (114147) +2 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Regeneration and expansion of Treg by low‐dose interleukin‐2 (IL‐2) therapy is considered a potential treatment strategy for a wide range of autoimmune diseases. To provide a pathophysiologically‐based rationale for low‐dose IL‐2 therapy, we investigated whether reversible defects in the Treg–IL‐2 axis emerge in inflammatory myopathies ...
Justus Ohmes +10 more
wiley +1 more source
Canine parvovirus-like particles, a novel nanomaterial for tumor targeting
Journal of Nanobiotechnology, 2006 Specific targeting of tumor cells is an important goal for the design of nanotherapeutics for the treatment of cancer. Recently, viruses have been explored as nano-containers for specific targeting applications, however these systems typically require ...
Destito Giuseppe +3 more
doaj +1 more source
Chemistry – A European Journal, EarlyView.ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source
The Ubiquity of Twisted Flux Ropes in the Quiet Sun
The Astrophysical Journal LettersModels and observations have demonstrated that twisted flux ropes (TFRs) play a significant role in the structure and eruptive dynamics of active regions.
Tahar Amari +8 more
doaj +1 more source