Results 41 to 50 of about 2,334 (199)

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity

Advanced Science, EarlyView.
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten, Karen Beets, Tessa Schalley, Janne Verreycken, Gayel Duran, Daphne Lintsen, Lisa Schuetz, Xue Zhong, Rinke Nieuwschepen, Melissa Schepers, Brecht Moonen, Jeroen Bogie, Jana Van Broeckhoven, Carlo Heirman, Jurgen Van den Heuvel, Bart Vanderborght, Ismael Varela, Roxanne Nouille, Lotte Jacobs, Jessica Filtjens, Sabah Kasmi, Elise Seynaeve, Veronica Mavrovouna, Jana De Vrieze, Michael A. Brehm, Sandra Maréchal, Sophie Janssens, Florence Lambolez, Niels Hellings, Stefaan De Koker, Bieke Broux   +30 more
wiley   +1 more source

Bağımsız Denetime Tabi Hastane Hizmeti Sunan TFRS ve BOBİ FRS’yi Uygulayan Sağlık Kuruluşlarının Karşılaştırmalı Finansal Analizi (2018-2022)

İşletme Bilimi Dergisi
Çalışmanın amacı, finansal tabloları bağımsız denetimden geçen özel hastanelerin finansal durumu ve performansının finansal açıdan analiz edilmesidir. Çalışmada nitel yöntem kullanılmıştır.
Enver Bozdemir
doaj   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Type of bilingualism conditions individual differences in the oscillatory dynamics of inhibitory control

Frontiers in Human Neuroscience, 2022
The present study uses EEG time-frequency representations (TFRs) with a Flanker task to investigate if and how individual differences in bilingual language experience modulate neurocognitive outcomes (oscillatory dynamics) in two bilingual group types ...
Sergio Miguel Pereira Soares, Sergio Miguel Pereira Soares, Yanina Prystauka, Vincent DeLuca, Jason Rothman, Jason Rothman   +5 more
doaj   +1 more source

Continuous‐Flow Microfluidic Synthesis Enhances C2+ Selectivity for Cu2O Catalysts

Advanced Science, EarlyView.
Microfluidic devices are used to prepare Cu2O nanoparticles under laminar flow conditions, which exhibit enhanced selectivity in the CO2‐to‐C2+ reaction due to their nanoporosity and high defect concentration. Cu2O prepared using standard solution methods displays decreased CO2‐to‐C2+ selectivity due to the absence of similar properties. Altogether, we
Carlota Casas, Anh Tuan Ngo, João Pedro Vale, Ona Falcó, Gerard Martí, Mohamed Amazian, Júlia Mayans, Sònia Estradé, Marcos Gil‐Sepulcre, Teresa Andreu, Francesca Peiró, Tiago Sotto Mayor, Lluís Yedra, Jordi García‐Antón, Josep Puigmartí‐Luis, Xavier Sala, Roc Matheu   +16 more
wiley   +1 more source

TMS-32, TMS-39 VE TFRS-7, TFRS-9 KAPSAMINDA FİNANSAL ARAÇLAR: SUNUM, MUHASEBELEŞTİRME, ÖLÇÜM VE AÇIKLAMALAR STANDARDINA İLİŞKİN BİR İNCELEME

Sosyal Ekonomik Araştırmalar Dergisi, 2014
Muhasebe uygulamalarına yön veren kurallar bütünü olarak adlandırılan standartların temeli muhasebe ilkelerine, muhasebe ilkelerinin temeli ise muhasebenin temel kavramlarına dayanmaktadır.
Yunus Ceran, Merve Öz
doaj   +1 more source

Achieve Sustainability by Easing Population to 4 Billion by 2200

Sustainable Development, EarlyView.
ABSTRACT The past century of massive increases in human population and resource use has seen many undesirable environmental effects, ranging from biodiversity loss to climate change. But a research gap exists, as the ultimate causes are often not described with precision or mentioned at all.
Mark Keegan, Anastasia Pseiridis, Philip Cafaro, Jane O'Sullivan, William Rees, Estelle Monique Sidze, Lawrence Whitmore, Enrique J. Derlindati, Mohammad Mainul Islam, Khaoula Houssini, S. Irudaya Rajan   +10 more
wiley   +1 more source

FİNANSAL YATIRIMLARIN TÜRKİYE MUHASEBE STANDARTLARI (TMS) VE TÜRKİYE FİNANSAL RAPORLAMA STANDARTLARI (TFRS) KAPSAMINDA MUHASEBELEŞTİRİLMESİ

Cumhuriyet Üniversitesi İktisadi ve İdari Bilimler Dergisi, 2015
Yeni Türk Ticaret Kanunu ile muhasebe kayıtlarının tutulması ve finansal tabloların düzenlenmesi, Uluslararası Muhasebe Standartları (UMS=IAS=International Accounting Standards) ve Uluslararası Finansal Raporlama Standartları (UFRS=IFRS=International ...
Şakir Dızman
doaj  

TÜRKİYE MUHASEBE STANDARTLARI KAPSAMINDA YATIRIM AMAÇLI GAYRİMENKULLERİN FİNANSAL TABLOLARDA SUNULUM ESASLARI VE MUHASEBE MESLEK MENSUPLARININ BİLGİ DÜZEYİNİ TESPİT ETMEYE YÖNELİK BİR ARAŞTIRMA

Sosyal Ekonomik Araştırmalar Dergisi, 2014
Türkiye’de kamuya hesap verme yükümlülüğü bulunan birçok işletme günümüzde Türkiye Muhasebe/Finansal Raporlama Standartlarını (TMS/TFRS) uygulamaktadır.
Ali Deran, İncilay Savaş, Atilla Sürer   +2 more
doaj   +1 more source