Results 71 to 80 of about 7,910 (230)

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Spatial and Temporal Regulation of Receptor Endocytosis in Neuronal Dendrites Revealed by Imaging of Single Vesicle Formation

Cell Reports, 2017
Endocytosis in neuronal dendrites is known to play a critical role in synaptic transmission and plasticity such as long-term depression (LTD). However, the inability to detect endocytosis directly in living neurons has hampered studies of its dynamics ...
Morgane Rosendale, Damien Jullié, Daniel Choquet, David Perrais   +3 more
doaj   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Development of a Mobile Device for Odor Identification and Optimization of Its Measurement Protocol Based on the Free-Hand Measurement

Sensors, 2020
Practical applications of machine olfaction have been eagerly awaited. A free-hand measurement, in which a measurement device is manually exposed to sample odors, is expected to be a key technology to realize practical machine olfaction.
Gaku Imamura, Genki Yoshikawa
doaj   +1 more source

Developmental Trends in Serum Iron, Transferrin, and Transferrin Saturation From Birth to 12 Months

Acta Paediatrica, EarlyView.
ABSTRACT Aim There is a need for updated reference intervals for iron status biomarkers during infancy. This study aimed to investigate reference interval trends and diurnal variation of iron, transferrin, and transferrin saturation in infants subjected to delayed cord clamping at birth (DCC). Methods Data analysis from population‐based Swedish studies,
Sara Marie Larsson, Lena Hellström‐Westas, Ulrica Askelöf, Cecilia Götherström, Magnus Domellöf, Ola Andersson   +5 more
wiley   +1 more source

Reticulocyte transferrin receptor (TfR) expression and contribution to soluble TfR levels.

Haematologica, 2001
Transferrin receptor (TfR) expression in erythroid cells is regulated by a number of factors, including iron status and erythropoietin (Epo) stimulation. However, the impact of these factors on reticulocyte TfR expression in vivo has never been studied. A soluble form of TfR (sTfR) is present in serum in proportion to the mass of cellular TfR. Although
R'Zik, Samir, Loo, Martine, Beguin, Yves
openaire   +2 more sources

Introducing a prognostic score for successful treatment‐free remission in chronic myeloid leukaemia

British Journal of Haematology, EarlyView.
Summary The modern management of chronic myeloid leukaemia (CML) identifies a new therapeutic goal of treatment‐free remission (TFR). Half of CML patients in durable deep molecular response (DMR) (MR4 or better) can remain off tyrosine kinase inhibitors (TKIs) without experiencing loss of major molecular response.
Simone Claudiani, Silvia Metelli, Afzal Khan, Guy Hannah, Jenny Byrne, Paolo Gallipoli, Simon J. Bulley, Gillian A. Horne, Kate Rothwell, Mhairi Copland, Richard E. Clark, Fiona Fernando, Andrew J. Innes, Jane F. Apperley, Dragana Milojkovic   +14 more
wiley   +1 more source

PEGylated Chitosan Nanoparticles: Engineering Multifunctional Platforms for Targeted Cervical and Lung Cancer Treatment

Cancer Science, EarlyView.
Graphical representation of formation of self‐assembled PEGylated Chitosan Nanoparticles and their mechanism in tumor localization. ABSTRACT Polymer‐based nanocarriers have emerged as transformative platforms in cancer nanomedicine, enabling controlled and site‐specific delivery of therapeutic agents.
Prashant Kesharwani, Nazim Nasir, Shadma Wahab, Garima Gupta, Khang Wen Goh, Amirhossein Sahebkar   +5 more
wiley   +1 more source

U.S. Population Projections: 2005-2050 [PDF]

, 2008
Projects population growth, new immigrants and their descendants as a percentage of that growth, and changes in the population's ethnic/racial composition.
D'Vera Cohn, Jeffrey S. Passel
core  

Internal kinematics of isolated modelled disk galaxies

, 2005
We present a systematic investigation of rotation curves (RCs) of fully hydrodynamically simulated galaxies, including cooling, star formation with associated feedback and galactic winds.
Boehm, A., Kapferer, W., Kronberger, T., Schindler, S., Ziegler, B. L.   +4 more
core   +1 more source