Results 81 to 90 of about 4,188,101 (180)

Nanoparticle Adjuvant Design Enhances Germinal Center Responses Targeting Conserved Subdominant Epitopes for Pan‐Coronavirus Vaccine Development

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Current SARS‐CoV‐2 vaccines generate short‐lived, strain‐specific immunity. A polymeric TLR7 agonist nanoparticle (TLR7‐NP) adjuvant enhances lymph node targeting and promotes early and sustained germinal center responses toward conserved S2 epitopes of the spike protein.
Sijin Huang, Kanella M. Cohen, Liqiang Chen, Xiaowo Kang, Chang Liu, Megan E. Demouth, Wenxia Jiang, Alexander R. Maldeney, Rong Tong, Zunlong Ke, Kartik Chandran, Wei Luo, Qian Yin   +12 more
wiley   +1 more source

Trends in Irish Fertility Rates in Comparative Perspective [PDF]

This paper examines trends in Irish fertility rates over the past four decades in the context of fertility trends in developed countries generally. Irish fertility rates have stabilised at the upper edge of the European range in the 1990s.
Tony Fahey
core  

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Tungsten fiber reinforced superalloys: A status review [PDF]

Improved performance of heat engines is largely dependent upon maximum cycle temperatures. Tungsten fiber reinforced superalloys (TFRS) are the first of a family of high temperature composites that offer the potential for significantly raising hot ...
Petrasek, D. W., Signorelli, R. A.
core   +1 more source

Evolution of the infrared Tully-Fisher relation up to z=1.4

, 2010
The Tully-Fisher relation (TFR) represents a connection between fundamental galaxy parameters, such as its total mass and the mass locked in stars. Therefore, the study of the evolution of this relation in the optical and infrared bands can provide ...
A. Bongiovanni, A. M. Pérez García, Bamford, Barmby, Benítez, Bertin, Blanton, Bosma, Bouwens, Bruzual, Bundy, Böhm, Calzetti, Coil, Conselice, Croton, Cuillandre, Davis, Davis, De Lucia, Drory, Faber, Fernández Lorenzo, Flores, Giovanelli, Grocholski, Hammer, Hewett, Horne, J. Cepa, Kassin, Laurikainen, M. A. Lara-López, M. Fernández Lorenzo, M. Pović, M. Sánchez-Portal, Mannucci, Masters, Mathewson, Nakamura, Navarro, Poggianti, Puech, Rix, Rodrigues, Schechter, Schlegel, Silva, Simard, Simard, Springel, Tacconi, Tremonti, Tully, Tully, Tully, van Starkenburg, Verheijen, Vogt, Vogt, Weiner, Weiner, Westera, Westera, Willick, Ziegler, Zwaan   +66 more
core   +1 more source

Transient Cyclic Structured Oligonucleotide Designs for Therapeutic Applications

Current Protocols, Volume 6, Issue 2, February 2026.
Abstract Oligonucleotide‐based therapeutics are now widely used in clinical settings. From the late 1980s to the mid‐1990s, efforts to improve therapeutic efficacy focused on imparting drug‐like properties to oligonucleotides, emphasizing nuclease stability and target sequence affinity.
Sudhir Agrawal
wiley   +1 more source

Advanced aircraft engine materials trends [PDF]

Recent activities of the Lewis Research Center are reviewed which are directed toward developing materials for rotating hot section components for aircraft gas turbines.
Dreshfield, R. L., Gray, H. R., Levine, S. R., Signorelli, R.   +3 more
core   +1 more source

Proteomic Analysis of Regulated Dendritic Cell Endosomes Reveals Dynamic Adaptation to Antigen Uptake and Cross‐Presentation

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Phagocytosis of yeast activates recruitment of proteases and trafficking factors from the secretory and endosomal pathways to the IRAP compartment and subsequently phagosomes, promoting cross‐presentation. In the absence of Sec22b, IRAP endosome and phagosome maturation to late endosomes is accelerated.
Alice Senni, Louise Grumbach, Sara Ceccacci, Mathieu Frechin, Nicolas Goudin, Ida Chiara Guerrera, Barbara Bertocci, Peter van Endert   +7 more
wiley   +1 more source

Health inequalities in the older population: the role of personal capital, social resources and socio-economic circumstances.

, 2003
Older people now constitute the majority of those with health problems in developed countries so an understanding of health variations in later life is increasingly important. In this paper, we use data from three rounds of the Health Survey for England,
Grundy, Emily, Sloggett, Andy
core   +1 more source

Deep cytomorphology identifies erythroid skewing and monocytic morphology to predict TKI sensitivity in CML patients

HemaSphere, Volume 10, Issue 2, February 2026.
Abstract The cellular composition of the chronic myeloid leukemia (CML) bone marrow (BM) beyond granulocyte enrichment remains poorly understood. We analyzed 1548 routinely stained BM aspirate slides from 598 patients across seven sites using deep learning‐based image analysis to identify cytomorphological markers predictive of major molecular response.
Katariina Luukkainen, Mikko Purhonen, Mikael Tatun, Kevin Hung, Oda Tafjord, Henri Sundquist, Stina Söderlund, Shady Adnan‐Awad, Anni Dohlen, Johanna Heikkinen, Perttu Koskenvesa, Lotta Joutsi‐Korhonen, Anna Lempiäinen, Sanna Siitonen, Satu Mustjoki, Naranie Shanmuganathan, Coral Bryce, Signe Danielsson, Henrik Hjorth‐Hansen, Ulla Olsson‐Strömberg, Takashi Kumagai, Shinya Kimura, David M. Ross, Oscar Brück   +23 more
wiley   +1 more source