Results 61 to 70 of about 5,802,216 (159)

Treatment‐free remission in CML patients with prior TKI failure is not influenced by previous BCR::ABL1 kinase domain mutations

British Journal of Haematology, EarlyView.
Simone Claudiani, Silvia Metelli, Myrto Katraki, Fiona Fernando, Andrew J. Innes, Chloe Hayden, Dragana Milojkovic   +6 more
wiley   +1 more source

Adapting UK Clinical Practise in Chronic Myeloid Leukaemia in Chronic Phase to Contemporary Management Recommendations: The ADAPT 2.0 Survey

European Journal of Haematology, Volume 117, Issue 4, Page 1072-1080, October 2026.
ABSTRACT Objective Chronic myeloid leukaemia in chronic phase (CML‐CP) treatment recommendations have changed substantially in recent years. The ADAPT 2.0 survey aimed to provide an updated understanding of CML‐CP management in the UK. Methods This healthcare professional (HCP) survey, conducted between December 2023 and June 2024, assessed treatment ...
Dragana Milojkovic, Nicholas C. P. Cross, Ketul Desai, Kathryn Frewin, Mhairi Copland   +4 more
wiley   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity

Advanced Science, Volume 13, Issue 53, 24 September 2026.
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten, Karen Beets, Tessa Schalley, Janne Verreycken, Gayel Duran, Daphne Lintsen, Lisa Schuetz, Xue Zhong, Rinke Nieuwschepen, Melissa Schepers, Brecht Moonen, Jeroen Bogie, Jana Van Broeckhoven, Carlo Heirman, Jurgen Van den Heuvel, Bart Vanderborght, Ismael Varela, Roxanne Nouille, Lotte Jacobs, Jessica Filtjens, Sabah Kasmi, Elise Seynaeve, Veronica Mavrovouna, Jana De Vrieze, Michael A. Brehm, Sandra Maréchal, Sophie Janssens, Florence Lambolez, Niels Hellings, Stefaan De Koker, Bieke Broux   +30 more
wiley   +1 more source

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley   +1 more source

“Securities portfolio in banks reporting according to TFRS-9 financial instruments standard and application in the Turkish banking sector”

TMS-39 ile TFRS-9 standartlarının ayrıntılarına ve aralarındaki farklılıklara yer verilmiş olan bu çalışmada, aynı zamanda yerel ve yabancı kurumlar tarafından yapılan etki analizleri de incelenmektedir.
Sungur, Kübra
core  

ACCOUNTING OF SALE AND LEASEBACK TRANSACTIONS ACCORDING TO TFRS 16 AND TAS 17 STANDARDS

, 2020
İşletmelerin finansal kiralama şirketine satmış olduğu varlığı daha sonra finansal kiralama şirketinden kiralaması anlamına gelensat-geri kirala yöntemi, Türkiye’de 6361 sayılı finansal kiralama, faktoring ve finansman şirketleri kanununun ...
Tulum, Saadet
core   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, Volume 6, Issue 9, September 2026.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Nine TFRs of interest and their divergent neighbors.

, 2012
Nine TFRs of interest and their divergent neighbors.
Leslie Cuthbertson (114147), Justin R. Nodwell (114148), Sang Kyun Ahn (114146)   +2 more
core   +1 more source

The possible impacts of Tas/ Tfrs applications on ratio analysis [PDF]

, 2015
Küreselleşme ile birlikte uluslararası düzeyde işletme karşılaştırmaları ve işletme değerlemesi önemli bir konu haline gelmiştir. Fakat ülkelerin farklı muhasebe sistemlerine sahip olmaları işletmelerin karşılaştırılmalarında ve analizlerinde sorunlara ...
Aydemir, Oğuzhan, Yenigün, Tekin
core   +1 more source