Results 51 to 60 of about 634,529 (208)
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
UN CAZ RAR DE INFECŢIE DE TRACT URINAR CU BURKHOLDERIA CEPACIA LA VÂRSTĂ PEDIATRICĂ [PDF]
Introducere. Burkholderia cepacia este un bacil aerob, gram negativ care nu fermentează glucoza, ce afectează în primul rând pacienţii imunocomprimaţi sau spitalizaţi.
Iulia Armean +2 more
doaj +1 more source
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
SEPSIS CU PNEUMOCOC LA UN COPIL CU SINDROM NEFROTIC [PDF]
Introducere. Sindromul nefrotic reprezintă una dintre cele mai frecvente patologii glomerulare întâlnită la vârsta pediatrică, având o incidenţă de 4,7 cazuri la 100.000 de copii.
Iulia Armean +2 more
doaj +1 more source
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Study of Isthmin-1 Levels and Serum Lipid Measurements in Patients with Metabolic Syndrome
Background: Metabolic syndrome (MetS) is a group of comorbidities that includes obesity, hypertension, and disturbances in carbohydrate and lipid metabolism. Isthmin-1 (ISM1) is a secreted protein that plays multiple roles in pathophysiological processes.
Suhair Abdul Raheem Ahmed +1 more
doaj +1 more source
TG&Y Office Employees' Bulletin
Newsletter published for employees of T. G. & Y.
TG & Y (Firm)
core +2 more sources
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source

