Results 251 to 260 of about 79,137 (281)

Vogt-Koyanagi-Harada Syndrome: Clinical Features, Immunogenetic Predisposition and PD-1 Inhibitor-Induced Forms-A Comprehensive Review. [PDF]

J Clin Med
Orłowska SM, Bednarczyk Ł, Morshed K, Tyniec M, Olczyk P.   +4 more
europepmc   +1 more source

Immune mechanisms driving clinical heterogeneity in oral lichen planus. [PDF]

Sci Rep
Pons-Fuster E, Conesa-Solano J, Gimeno-Arias L, Martí-De Gea K, Alguazas I, Ruiz-Lorente I, Minguela A, López-Jornet P.   +7 more
europepmc   +1 more source

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Autoimmune thyroid diseases and Th17/Treg lymphocytes

Life Sciences, 2018
Years of researches have demonstrated that the imbalance of Th17 and Tregs contribute to the thyroid autoimmunity and the severity of autoimmune thyroid disease (AITD). The underlying mechanism comprises inherent genetic predisposition, abnormality of Th17 and Treg related biological molecules, and gut microbiota disorder.
Shiying Shao, Xuefeng Yu
exaly   +3 more sources

Activation of Peripheral Th17 Lymphocytes in Patients with Asthma

Immunological Investigations, 2009
A recently identified interleukin (IL)-17-producing T-helper (Th) lymphocyte subset, which comprises Th17 cells producing hallmark cytokines IL-17A, IL-17F and IL-22, is involved in chronic inflammatory diseases. Elevated gene and protein expressions of IL-17 are manifested in allergic asthma.
C K Wong, I H S Chan, David S C Hui
exaly   +3 more sources

Th17 and Th1 Lymphocytes Are Correlated with Chronic Periodontitis

Immunological Investigations, 2016
T cells are involved in the homeostasis of periodontal tissues and mediate bone loss in periodontitis, but the involvement of T-helper cells in chronic periodontitis (CP) in a Chinese population is still unclear. This study aimed to assess the distribution of peripheral and local T helper (Th17) and Th1 in CP.
Xiao-Tao, Chen, Li-Li, Chen, Jing-Yi, Tan, Dan-Hui, Shi, Ting, Ke, Li-Hong, Lei   +5 more
openaire   +2 more sources

Factors of Th17 and Treg Lymphocyte Differentiation in Pulmonary Tuberculosis

Bulletin of Experimental Biology and Medicine, 2015
In patients with infiltrative pulmonary tuberculosis, the increase in IL-6 secretion, the decrease in TGFβ production (in case of drug resistance of the causative agent), and unchanged level of IL-1β secretion by mononuclear leukocytes in vitro were associated with increased number of CD4(+)CD161(+)IL-17A(+) Th17 lymphocytes in the peripheral blood. In
T E, Kononova, O I, Urazova, V V, Novitskii, Yu V, Kolobovnikova, E G, Churina, P A, Zakharova   +5 more
openaire   +2 more sources

The role of Th17 lymphocytes in the autoimmune and chronic inflammatory diseases

Internal and Emergency Medicine, 2011
The emerging role of interleukin-17 as a hallmark proinflammatory cytokine of the adaptive immune system produced by a new T helper cell subset termed "Th17" has received considerable attention. In this review we will focus on recent information regarding IL-17 and its relevance in autoimmune and chronic inflammatory diseases.
MURDACA, GIUSEPPE, Colombo B.M., PUPPO, FRANCESCO   +2 more
openaire   +2 more sources

Tregs and Th17 lymphocytes in human DYRK1A haploinsufficiency

Immunology Letters, 2019
The DYRK1A gene encodes for a dual-specific tyrosine phosphorylation-regulated kinase 1A involved in different cellular processes such as cell differentiation, proliferation and survival. This tyrosine kinase plays a key role in brain growth and function.
Valencic E., Piscianz E., Sirchia F., Tommasini A., Faletra F., Todaro F., Spinelli A. M., Badolato R.   +7 more
openaire   +4 more sources

The role of Th17 lymphocytes in drug-resistant epilepsy

The Journal of Immunology, 2019
Abstract Epilepsy is a chronic neuronal disorder affecting ~65 millions people throughout the world. 1/3 of patients suffer from drug-resistant epilepsy (DRE). Objective to assess the relationship between different Th17 markers and the clinical course of epilepsy to uncover new ...
Oumarou Ouédraogo, Hélène Jamann, Audrey Daigneault, Marie-Laure Clenet, Boaz Lahav, A Bérubé, Patrick Cossette, Mark Keezer, Dang Khoa Nguyen, Catherine Larochelle   +9 more
openaire   +1 more source