Technical Comparison of Treatment Efficiency of Magnetic Resonance-Guided Focused Ultrasound Thalamotomy and Pallidotomy in Skull Density Ratio-Matched Patient Cohorts [PDF]
ObjectiveMR-guided focused ultrasound (MRgFUS) is increasingly being used to treat patients with essential tremor (ET) and Parkinson's disease (PD) with thalamotomy and pallidotomy, respectively.
Abdul-Kareem Ahmed+11 more
doaj +3 more sources
Altered Activation in Cerebellum Contralateral to Unilateral Thalamotomy May Mediate Tremor Suppression in Parkinson's Disease: A Short-Term Regional Homogeneity fMRI Study. [PDF]
BACKGROUND:Ventral intermediate nucleus thalamotomy is an effective treatment for Parkinson's disease tremor. However, its mechanism is still unclear. PURPOSE:We used resting-state fMRI to investigate short-term ReHo changes after unilateral thalamotomy ...
Zhi Wen+5 more
doaj +5 more sources
Stereotaxic Thalamotomy for Pain Relief
As a preliminary experimental study, the activity of single units of the thalamic pulvinar nucleus was studied in cats, and it was found that some of the pulvinar neurons responded to nociceptive stimuli such as pinpricks with a needle and pinching with toothed forceps.
Tatsuyuki KUDO+5 more
openalex +6 more sources
Novel Objective Tool to Assess Tremor Reveals Unilateral Focused Ultrasound Improves Tremor Bilaterally [PDF]
Background Tremor in essential tremor and in tremor-dominant Parkinson’s disease is assessed by subjective observations in patients undergoing focused ultrasound thalamotomy, a minimally invasive procedure intended to alleviate tremor in these patients ...
Vered Aharonson+7 more
doaj +2 more sources
Stereotactic ventrolateral thalamotomy for parkinsonians [PDF]
This series explored the symptomatic and functional impact of ventralis lateralis (VL) thalamotomy on 32 patients with severe, refractory tremor and rigidity due to Parkinson’s disease […] Stereotactic ventrolateral thalamotomy for ...
Sebastião Carlos Da Silva
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Levodopa-induced dyskinesia and thalamotomy. [PDF]
Levodopa-induced dyskinesia of the limbs in thirteen cases of Parkinsonism, which was choreic, ballistic or dystonic in type, was alleviated almost completely by stereotaxic surgery using a microelectrode technique for the ventralis oralis anterior and posterior nuclei of the thalamus, but much less by the ventralis intermedius nucleus.
Hirotaro Narabayashi+2 more
openalex +5 more sources
New technique for direct targeting of the ventral intermediate nucleus using magnetic resonance-guided focused ultrasound [PDF]
BackgroundAccurate targeting and lesion placement are critical in treating movement disorders with magnetic resonance-guided focused ultrasound (MRgFUS). Indirect atlas-based targeting often lacks precision. Direct anatomical targeting with 3T MRI offers
Juan Ángel Aibar-Duran+3 more
doaj +2 more sources
Profiling functional networks identify activation of corticostriatal connectivity in ET patients after MRgFUS thalamotomy [PDF]
Background: MR-guided focused ultrasound (MRgFUS) thalamotomy is a novel and effective treatment for medication-refractory tremor in essential tremor (ET), but how the brain responds to this deliberate lesion is not clear.
Jiaji Lin+7 more
doaj +2 more sources
Quantitative and qualitative tremor evaluation after MR-guided focused ultrasound thalamotomy [PDF]
IntroductionTremor syndromes are common neurological disorders, usually distinguished by clinical examination. Ordinal rating scales are widely used to rate tremor severity but are limited by subjective observation, interrater reliability, ceiling ...
Veronika Purrer+12 more
doaj +2 more sources
Cerebello-Thalamo-Cortical MR Spectroscopy in Patients with Essential Tremor Undergoing MRgFUS Thalamotomy: A Pilot Study [PDF]
Previous literature studies explored the association between brain neurometabolic changes detected by MR spectroscopy and symptoms in patients with tremor, as well as the outcome after deep brain stimulation (DBS) treatment.
Federico Bruno+19 more
doaj +2 more sources