Results 181 to 190 of about 5,288 (238)

Focused Ultrasound Central Lateral Thalamotomy for the Treatment of Refractory Neuropathic Pain: Phase I Trial

Neurosurgery, 2023
BACKGROUND AND OBJECTIVES: Magnetic resonance–guided focused ultrasound (MRgFUS) central lateral thalamotomy (CLT) has not yet been validated for treating refractory neuropathic pain (NP). Our aim was to assess the safety and potential efficacy of MRgFUS
Abdul-Kareem Ahmed, J. Zhuo, R. Gullapalli, Li Jiang, M. Keaser, J. Greenspan, Chixiang Chen, Timothy R Miller, Elias R. Melhem, C. Sansur, Howard Eisenberg, Dheeraj Gandhi   +11 more
semanticscholar   +1 more source

Microelectrode Recording and Radiofrequency Thalamotomy following Focused Ultrasound Thalamotomy

Stereotactic and Functional Neurosurgery, 2020
Magnetic resonance imaging-guided focused ultrasound (MRgFUS) is a novel method for stereotactic brain lesioning and has primarily been applied for thalamotomies to treat essential tremor (ET). The electrophysiological properties of previously MRgFUS-sonicated thalamic neurons have not yet been described.
Luka Milosevic, Luka Milosevic, Andres M. Lozano, Andres M. Lozano, Robert F. Dallapiazza, Philippe De Vloo, Philippe De Vloo, Robert Gramer, Robert Gramer, Alfonso Fasano, Alfonso Fasano, Michael L. Schwartz, Suneil K. Kalia, Suneil K. Kalia, Darrin J. Lee, William D. Hutchison, William D. Hutchison   +16 more
openaire   +3 more sources

Patient-Reported Outcomes After Focused Ultrasound Thalamotomy for Tremor-Predominant Parkinson's Disease

Neurosurgery, 2023
BACKGROUND: Magnetic resonance–guided focused ultrasound (MRgFUS) has emerged as a precise, incisionless approach to cerebral lesioning and an alternative to neuromodulation in movement disorders.
MD Georgios A. Maragkos, BS ‡ Jacob Kosyakovsky, BS ‡ Patricia Zhao, MD Kathryn N. Kearns, Msn RN Cnrn Shelly Rush-Evans, MD Shayan Moosa, MD W. Jeffrey Elias   +6 more
semanticscholar   +1 more source

A phase 1 open‐label trial evaluating focused ultrasound unilateral anterior thalamotomy for focal onset epilepsy

Epilepsia, 2023
Focused ultrasound ablation (FUSA) is an emerging treatment for neurological and psychiatric diseases. We describe the initial experience from a pilot, open‐label, single‐center clinical trial of unilateral anterior nucleus of the thalamus (ANT) FUSA in ...
V. Krishna, Jesse W. Mindel, F. Sammartino, C. Block, A. Dwivedi, Jamie J Van Gomple, N. Fountain, R. Fisher   +7 more
semanticscholar   +1 more source

Action tremor and thalamotomy

Electroencephalography and Clinical Neurophysiology, 1969
Abstract During the pre-operative study of eight Parkinsonian patients, two men were found to have a typical “action tremor”. Voluntary contraction of the biceps was produced by a rhythmic discharge of motor units at a frequency of 9–12 c/sec. The unloading reflex was abnormal, with bursts of tremor activity occurring when the “silent period” would ...
J.A Aguilar, J.A Aguilar, W.W. Hofmann, W.W. Hofmann, Ronald W. Angel, Ronald W. Angel   +5 more
openaire   +2 more sources

Hemorrhagic Safety of Magnetic Resonance-Guided Focused Ultrasound Thalamotomy for Tremor without Interruption of Antiplatelet or Anticoagulant Therapy

Stereotactic and Functional Neurosurgery, 2023
Introduction: Magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy is an incision-less ablative technique used to treat medically refractory tremor.
Rose M. Caston, Justin M. Campbell, Shervin Rahimpour, Paolo Moretti, Matthew D. Alexander, John Rolston   +5 more
semanticscholar   +1 more source

[Experience of staged and simultaneous bilateral thalamotomy using MR-guided focused ultrasound in the treatment of essential tremor].

Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova, 2023
OBJECTIVE To show that effective and safe bilateral MR-guided focused ultrasound (MRgFUS) treatment of essential tremor (ET) is achievable. MATERIAL AND METHODS Four male patients underwent bilateral thalamotomy.
D. Nabiullina, R. Galimova, S. Illarioshkin, I. Buzaev, S. Safin, G. Akhmadeeva, N. Mukhamadeeva, D. Krekotin   +7 more
semanticscholar   +1 more source

Thalamotomy for Parkinsonian Tremor

Stereotactic and Functional Neurosurgery, 1997
Thalamotomy for parkinsonian tremor was performed in 25 patients. A good outcome was achieved in 66% of cases. Three patients sustained a significant new deficit. Stimulation through the lesioning electrode provided an adequate means of corroboration of target localisation.
Brian P. Brophy, P.D. Thompson, T.J. Kimber   +2 more
openaire   +3 more sources

Linear accelerator thalamotomy

Surgical Neurology, 2004
The capability of performing functional radiosurgery lesions in the brain using a dedicated linear accelerator (LINAC) have not yet been demonstrated. This study evaluates modern LINAC technology for the creation of a sharp, small and functionally eloquent lesion in the thalamus.Three patients underwent thalamotomy using a dedicated linear accelerator ...
Robert E. Wallace, Antonio A.F. De Salles, Cynthia Cabatan-Awang, Leonardo Frighetto, Judith M. Ford, Michael T. Selch, Timothy D. Solberg   +6 more
openaire   +2 more sources

Focused Ultrasound Thalamotomy: Correlation of Postoperative Imaging with Neuropathological Findings

Stereotactic and Functional Neurosurgery, 2023
Magnetic resonance-guided high-intensity focused ultrasound (MRgFUS) is a rapidly developing technique used for tremor relief in tremor-predominant Parkinson’s disease (PD) and essential tremor that has demonstrated successful results.
Sarah E. Blitz, M. Torre, M. Chua, Sarah L. Christie, N. McDannold, G. Cosgrove   +5 more
semanticscholar   +1 more source