Results 71 to 80 of about 5,288 (238)

Evaluation of the efficacy and safety of MRI-guided focused ultrasound (MRgFUS) for focal hand dystonia: study protocol for an open-label non-randomised clinical trial

BMJ Neurology Open, 2023
Introduction MRI-guided focused ultrasound (MRgFUS) thalamotomy provides an exciting development in the field of minimally invasive stereotactic neurosurgery.
Yael Barnett, James Peters, Stephen Tisch, Diane Ruge, Kain Kyle, Joel Maamary, Benjamin Jonker   +6 more
doaj   +1 more source

Pretherapeutic functional connectivity of tractography-based targeting of the ventral intermediate nucleus for predicting tremor response in patients with Parkinson's disease after thalamotomy with MRI-guided focused ultrasound.

Journal of Neurosurgery, 2022
OBJECTIVE Tractography-based direct targeting of the ventral intermediate nucleus (T-VIM) is a novel method that provides patient-specific VIM coordinates.
Yongqin Xiong, Jiaji Lin, Longsheng Pan, R. Zong, Xiangbing Bian, Caohui Duan, Dekang Zhang, X. Lou   +7 more
semanticscholar   +1 more source

Myoclonic Dystonia: A Common Phenomenology in the Pleomorphic Movements of Angelman Syndrome

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Angelman syndrome (AS) is a neurodevelopmental disorder characterized by developmental delay, intellectual disability, a sociable demeanor, and abnormal movements. People with AS often exhibit multiple types of abnormal movements, including nonepileptic myoclonus, tremor, and dystonia, which hamper attempts to identify phenomenology
Robert P. Carson, Heather Riordan, Brittany Short, Thomas Davis, John Fang, Andrew Giritharan, David A. Isaacs, Joanna Blackburn, Bhooma Aravamuthan   +8 more
wiley   +1 more source

Treatment-Specific Network Modulation of MRI-Guided Focused Ultrasound Thalamotomy in Essential Tremor

Neurotherapeutics, 2022
MRI-guided focused ultrasound (MRgFUS) thalamotomy is a novel, effective, and non-invasive treatment for essential tremor (ET). However, the network mediating MRgFUS in treating ET is not precisely known. This study aimed to identify the disease-specific
Yongqin Xiong, Jiaji Lin, Xiangbing Bian, Haoxuan Lu, Jiayou Zhou, Dekang Zhang, Longsheng Pan, Xin Lou   +7 more
semanticscholar   +1 more source

Deep Brain Stimulation of the Subthalamic Nucleus in Patients with Parkinson Disease with Prior Pallidotomy or Thalamotomy

Brain Sciences, 2018
Objective. To evaluate the efficacy of deep brain stimulation of the subthalamic nucleus (STN DBS) in patients with Parkinson disease (PD) who previously underwent lesioning of the basal ganglia. Material and methods.
Elena A. Khabarova, Natalia P. Denisova, Aleksandr B. Dmitriev, Konstantin V. Slavin, Leo Verhagen Metman   +4 more
doaj   +1 more source

Stereotactic Lesioning of the Thalamic Vo Nucleus for the Treatment of Writer's Cramp (Focal Hand Dystonia)

Frontiers in Neurology, 2018
Writer's cramp (focal hand dystonia) is a sporadic focal dystonia that affects a specific part of the upper limb causing excessive co-contraction of antagonistic muscles.
Takeshi Shimizu, Takeshi Shimizu, Tomoyuki Maruo, Tomoyuki Maruo, Shimpei Miura, Shimpei Miura, Haruhiko Kishima, Yukitaka Ushio, Satoshi Goto   +8 more
doaj   +1 more source

Focused ultrasound resolves persistent radiosurgery related change in a patient with tremor

Radiology Case Reports, 2019
We report on a patient who underwent magnetic resonance guided focused ultrasound (MRgFUS) thalamotomy to treat tremor 3 years after a stereotactic radiosurgery (SRS) thalamotomy.
Erin L. Mazerolle, PhD, Graham M. Seasons, Robyn Warwaruk-Rogers, BNSc, Paul Romo, RT, Robert Nordal, MD, Robert J. Sevick, MD, Davide Martino, MD, Samuel Pichardo, PhD, Zelma H.T. Kiss, MD PhD, Gilbert Bruce Pike, PhD   +9 more
doaj  

Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Individual variability in clinical response to dopamine replacement therapy (DRT) is a key barrier to efficacious treatment for patients with Parkinson's disease (PD). A better understanding of the neurobiological sources of such interindividual differences is necessary to personalize DRT prescribing, inform future clinical ...
Alex I. Wiesman, Mikkel C. Vinding, Panagiota Tsitsi, Per Svenningsson, Josefine Waldthaler, Daniel Lundqvist   +5 more
wiley   +1 more source

Assessing the impact of MR-guided focused ultrasound thalamotomy on brain activity and connectivity in patients with essential tremor.

Neurosurgical Focus, 2022
OBJECTIVE Although magnetic resonance-guided focused ultrasound (MRgFUS) at the ventral intermediate (VIM) thalamic nucleus is a novel and effective treatment for medication-refractory essential tremor (ET), it is unclear how the ablation lesion affects ...
Haoxuan Lu, Jiaji Lin, Yongqin Xiong, Linlin Deng, Xiaoyu Wang, Dekang Zhang, Xiangbing Bian, Jiayou Zhou, Longsheng Pan, Xin Lou   +9 more
semanticscholar   +1 more source

Bilateral Focused Ultrasound Thalamotomy for Essential Tremor: Clinical Outcomes Compared to Bilateral Deep Brain Stimulation and Probabilistic Lesion Mapping

Movement Disorders, EarlyView.
Abstract Background The efficacy and adverse events (AEs) of bilateral magnetic resonance‐guided focused ultrasound (MRgFUS) thalamotomies for essential tremor (ET) have not been compared to those of deep brain stimulation (DBS). Furthermore, it is uncertain whether second‐side thalamotomies can be positioned differently from the first without ...
Can Sarica, Kazuaki Yamamoto, Christian Iorio‐Morin, Jurgen Germann, Andrew Z. Yang, Brendan Santyr, Michael Colditz, Artur Vetkas, Anton Fomenko, Benjamin Davidson, Franziska Schmidt, Talyta Grippe, Nardin Samuel, Ajmal Zemmar, Oliver Flouty, Cletus Cheyuo, Ghazaleh Darmani, Robert Chen, Alexandre Boutet, Clemens Neudorfer, Mojgan Hodaie, Suneil K. Kalia, Renato P. Munhoz, Alfonso Fasano, Andres M. Lozano   +24 more
wiley   +1 more source